Clinical trials
Dry Eye Symptoms clinical trials
Below are recruiting dry eye symptoms clinical trials, each written for real people, not researchers. We’re tracking 31 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07659626Recruiting
Long-term effects of Acoltremon for dry eye disease
This study tests a new medication called Acoltremon to see if it helps dry eye symptoms over a long period. If you've had dry eye for a while and used artificial tears, this trial might be for you.
Louisville, KentuckyAges 18 years+ - NCT07273747Recruiting
Kelulut honey for eye allergy and dry eye
This study tests if Kelulut honey eye drops can help people with both allergic conjunctivitis (eye allergies) and dry eye symptoms. If you have been diagnosed with eye allergies and still have bothersome symptoms despite treatment, this trial may offer a natural option to explore.
Kota Bharu, KelantanAges 18–40 - NCT07451184RecruitingPhase 4
Comparing eye drops for dry eye relief
This study compares two different eye drop lubricants to see which one works better for people with dry eye symptoms. You would use only the study drops for the whole time and attend a few visits to check your eyes.
Waterloo, OntarioAges 18 years+ - NCT07453212Enrolling by invitation
Food supplement for dry eye caused by meibomian gland issues
This trial tests a food supplement designed to improve dry eye symptoms by targeting the microbiome. It may help if you have dry eye due to meibomian gland problems and are not using contact lenses or certain other eye treatments.
IstanbulAges 18–65 - NCT07413172RecruitingPhase 2
Testing serum tears for severe dry eye
This study tests whether eye drops made from your own blood serum (with a natural lubricant) can relieve moderate-to-severe dry eye better than a standard salt solution. If you have dry eye from certain immune conditions or nerve damage, this may help find a more effective treatment.
Miami, FloridaAges 18 years+ - NCT06615453Recruiting
Tixel treatment for dry eye disease and periorbital wrinkles
This study tests a device called Tixel that may help reduce wrinkles around the eyes and improve dry eye symptoms. If you have mild to moderate under-eye wrinkles and dry eyes that bother you a lot, this treatment might be an option.
BirminghamAges 18 years+ - NCT06696625Recruiting
Nerve stimulation for dry eye relief
This trial tests if mild electrical pulses on the ear can reduce dry eye symptoms. If you have had dry eye for at least 6 months and meet certain eye test results, this non-drug treatment might help.
Beijing, Beijing MunicipalityAges 18–65 - NCT06780293RecruitingPhase 2
Laser acupuncture for dry eye and Sjogren's dry eye
This study tests if laser acupuncture can help people with dry eye symptoms, including those with Sjogren's syndrome, which causes dryness in the eyes and mouth. It may be a good fit if you have dry eye or Sjogren's and meet the age and eye test requirements.
Taipei, TaiwanAges 20–75 - NCT07191847RecruitingPhase 4
Stem cell eye drops for dry eye disease
This trial tests whether stem cell fortified eye drops can improve tear film stability, tear volume, and dry eye symptoms. If you have dry eye disease and haven't had eye surgery or certain other eye conditions, you may be able to join.
GizaAges 18–80 - NCT07266948RecruitingPhase 4
How TRYPTYR eye drops affect dry eye symptoms and daily life
This study tests a new eye drop called TRYPTYR to see if it can improve quality of life and daily tasks for people with dry eye disease who are unhappy with their current treatment, Restasis. Participants will stop using Restasis and switch to TRYPTYR for about 4 weeks.
Pittsburg, KansasAges 18–75 - NCT07676084RecruitingPhase 4
Over-the-counter lubricating eye drops for dry eye
This study tests whether over-the-counter lubricating eye drops can improve dry eye symptoms and eye comfort. It compares the drops to no treatment to see how well they work.
Andover, MassachusettsAges 18 years+ - NCT07618364Recruiting
Rinsing to reduce eye inflammation in dry eye disease
This study tests whether rinsing the eye surface helps reduce inflammation and symptoms in people with dry eyes. Participants must have a specific inflammatory marker (MMP-9) in both eyes.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06879782RecruitingPhase 3
Eye drops for dry eye disease: a phase 3 study
This study tests an eye drop called lifitegrast for people with dry eye disease. It looks at whether the drops can improve eye comfort, reduce dryness, and help eye surface health. You may be able to join if you have had dry eye symptoms and used artificial tears in the past month.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07298811RecruitingPhase 1/Phase 2
Healthy eye bacteria for dry eye treatment
This study tests whether putting healthy bacteria from a family member's eye surface onto your eyes can help treat moderate to severe dry eye. You would receive standard dry eye drops plus the experimental transplant.
Nanchang, JiangxiAges 18–70 - NCT07412860Recruiting
Eye drop test for moderate to severe dry eye
This trial tests a new eye drop (FBV_01) compared to a standard hyaluronic acid eye drop for people with moderate to severe dry eye. The goal is to see if the new drop provides better relief.
Cagliari, CAAges 18 years+ - NCT07623382RecruitingEarly Phase 1
Stem Cell Treatment for Dry Eye Disease
This early-stage trial tests whether special cells derived from umbilical cord tissue can help treat dry eye disease. The treatment uses tiny particles called extracellular vesicles that may reduce eye dryness and improve comfort.
Xiamen, ChinaAges 18 years+ - NCT07656688RecruitingPhase 2
Finding the best dose for a dry eye treatment
This trial tests different doses of a new eye drop (HUC1-394) to see which dose works best for people with moderate to severe dry eye disease. You may qualify if your dry eye symptoms have lasted at least 3 months and you have low tear production along with other signs of dry eye.
SeoulAges 19 years+ - NCT07171710Enrolling by invitation
Cyclosporine eye drops and tear duct plugs for dry eye in Sjögren's
This trial tests if using special eye drops (cyclosporine) along with tiny plugs placed in the tear ducts can improve dry eye symptoms in people with Sjögren's syndrome. The goal is to see if this combination works better than the drops alone.
Tianjin, Tianjin MunicipalityAges Any age - NCT07732010RecruitingPhase 4
Tryptophan for dry eye disease
This trial tests whether a dietary supplement called TRYPTYR can improve dry eye symptoms. You may qualify if you have moderate dry eye with certain signs, like short tear breakup time and staining on your eye surface.
New York, New YorkAges 18 years+ - NCT07268599Enrolling by invitation
Acoltremon for moderate-to-severe dry eye relief
This study tests a new eye drop called Acoltremon to see if it can relieve symptoms of moderate-to-severe dry eye disease. It may be a good option if you have had dry eye for at least 6 months and use artificial tears.
Encino, CaliforniaAges 18–60 - NCT06976515Recruiting
Remote study for evaporative dry eye disease
This study tests if people with evaporative dry eye can monitor their condition from home using a smartphone app and mail-in tests. No treatment is given; the goal is to see if remote research is possible.
San Francisco, CaliforniaAges 18 years+ - NCT07566975Recruiting
How VEVYE Helps Dry Eye in Neuro-Eye Patients
This study tracks whether VEVYE®, a prescription eye drop, reduces dry eye symptoms and signs in people who have both a neuro-ophthalmic condition (a nerve or brain issue affecting the eyes) and dry eye disease. You'll visit the clinic for 6 months and answer questions about your eye comfort.
Houston, TexasAges 18 years+ - NCT03358979Recruiting
3D eye-surface testing for severe dry eye
This study looks at how a specific eye-surface marker (EMMPRIN) changes on the surface cells in people with severe dry eye. It may help researchers understand disease severity and how new treatments could work for severe symptoms.
ParisAges 18 years+ - NCT07155070RecruitingPhase 4
Can eye drops help LASIK recovery?
This trial tests if Kera Sol Tears eye drops can reduce eye discomfort after LASIK surgery. If you are planning to have LASIK, this study may help you feel better during recovery.
Sioux Falls, South DakotaAges 18 years+
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Common questions
- Are there clinical trials for dry eye symptoms?
- Yes. Clin2 currently lists 31 recruiting dry eye symptoms studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a dry eye symptoms trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a dry eye symptoms trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.