Clinical trials
Effectiveness clinical trials
Below are recruiting effectiveness clinical trials, each written for real people, not researchers. We’re tracking 6,371 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06587256RecruitingPhase 2
Studying silicone mouth tape for snoring and mild sleep apnea
This trial tests if wearing silicone tape over your mouth at night can help reduce snoring and improve mild sleep apnea. You will use the tape and report how you and your partner feel about your snoring.
Baltimore, MarylandAges 18–75 - NCT06596577Enrolling by invitationPhase 3
Improving access to specialty palliative care in hospitals
This trial tests if nudging healthcare providers can ensure that patients with serious illnesses receive the right kind of palliative care while in the hospital. It aims to make care more equitable and accessible.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06598397RecruitingPhase 4
Quit smoking help for people with HIV in NYC
This study is testing different ways to help people with HIV quit smoking. It combines medication, coaching, and text messages to find the most affordable and effective support.
New York, New YorkAges 18 years+ - NCT06583564Enrolling by invitation
ICG dye during surgery for stage III colorectal cancer
This study tests whether using a special dye during surgery helps people with stage III colorectal cancer stay cancer-free longer. The dye, called indocyanine green (ICG), makes tumors and lymph nodes glow under a special camera, helping surgeons remove them more precisely.
Changning, Shanghai MunicipalityAges 18 years+ - NCT06584422Recruiting
Online program for depression in older adults
This study tests an online program called Empower@Home that helps older adults with symptoms of depression. It compares the program to usual care to see if it improves mood and well-being.
Ann Arbor, MichiganAges 50 years+ - NCT06599307RecruitingPhase 2
Rituximab for thinking and hand function in advanced MS
This trial tests whether the drug rituximab can help people with secondary progressive MS keep their thinking and hand abilities from getting worse. It is for people with more advanced disability.
Giza, Giza GovernorateAges 18 years+ - NCT06586177Recruiting
Study on Long-Term Effects of B Cell Therapies for MS
This study looks at how B cell therapies (a type of medicine for MS) create a long-lasting effect in people with relapsing-remitting multiple sclerosis. It aims to understand how these treatments work over time so doctors can better predict benefits and risks.
DüsseldorfAges 18–60 - NCT06597149Recruiting
Ear stimulation for insulin levels in healthy volunteers
This study tests whether a gentle electrical stimulation in the ear can change insulin levels in the blood. It is for healthy adults who are willing to have small sensors and a blood draw.
Indianapolis, IndianaAges 18–70 - NCT06593639Recruiting
Prehabilitation for head and neck cancer patients
This study tests a prehabilitation program (exercise and nutrition support) to see if it helps patients with head and neck cancer who are about to start curative treatment. It aims to improve your strength and recovery before and during cancer therapy.
Naples, ItalyAges 18 years+ - NCT06585033Recruiting
Spinal cord stimulation for pain after back surgery
This trial tests how much of the pain relief from spinal cord stimulation is due to the placebo effect. It is for people with ongoing leg pain after back surgery who have already tried other treatments without success.
ArnhemAges 18–70 - NCT06422741Recruiting
Grape seed extract for cholesterol in night shift workers
This study tests whether a grape seed extract supplement can help lower LDL (bad) cholesterol in people who work rotating night shifts. It is looking for healthy adults with moderately high cholesterol who are not taking cholesterol medicine.
Reus, TarragonaAges 18 years+ - NCT06451913RecruitingPhase 4
Probiotic for gut health during Lyme disease antibiotics
This trial tests if a probiotic (Saccharomyces boulardii) can help maintain healthy gut bacteria while you take antibiotics for the early skin rash of Lyme disease (erythema migrans). You'll take amoxicillin for 14 days, plus either the probiotic or a placebo.
LjubljanaAges 18 years+ - NCT06575192RecruitingPhase 3
Breast reconstruction study with ARTIA matrix
This study tests a new supportive mesh called ARTIA for women having breast reconstruction immediately after a mastectomy. The mesh is placed under the skin to help hold a breast implant in position during a two-stage reconstruction process.
Los Angeles, CaliforniaAges 18 years+ - NCT06575426RecruitingPhase 1/Phase 2
Pig pancreatic cell transplant for type 1 diabetes
This trial tests a new treatment made from pig pancreatic cells (called OPF-310) that are placed under the skin to help control blood sugar in people with type 1 diabetes. It is for those whose diabetes is difficult to manage and who have dangerous low blood sugar episodes.
Chicago, IllinoisAges 35–70 - NCT06567340Recruiting
AI-guided care for depression in talking therapies
This trial tests whether an AI tool can help therapists choose the best treatment for depression. If you are 18 or older and have significant depression symptoms (PHQ-9 score of 10 or more), you may be able to join if you are already being treated at a participating Talking Therapies service.
Darlington, DurhamAges 18 years+ - NCT03878849RecruitingPhase 2
Study drug 2X-121 for ovarian cancer that keeps coming back
This Phase 2 trial tests whether 2X-121 can shrink or control ovarian, fallopian tube, or primary peritoneal cancer that is resistant to platinum chemotherapy. It enrolls people who have had limited prior treatment and can provide a recent or stored tumor sample.
Oklahoma City, OklahomaAges 18 years+ - NCT06579261Recruiting
Shamanism for fibromyalgia pain relief
This study tests whether core shamanism (a type of guided meditation and energy work) can help reduce pain in women with fibromyalgia. If you join, you would receive shamanic treatments up to twice a week at the study site in California.
Irvine, CaliforniaAges 18–75 - NCT06568198RecruitingPhase 2
Brain stimulation study for chronic low back pain
This trial tests whether a noninvasive brain stimulation technique called tACS can help reduce chronic low back pain. Participants will have brain scans and receive the treatment over several sessions.
Charlestown, MassachusettsAges 18–60 - NCT06571565Enrolling by invitationEarly Phase 1
Manual lymph drainage for fibromyalgia patients
This trial tests whether manual lymph drainage (a gentle massage technique that helps move fluid in the body) can help reduce pain and other symptoms in women with fibromyalgia. It may offer a new, drug-free option to feel better.
Adana, çukurovaAges 25 years+ - NCT06573996Recruiting
Testing a mouth TENS device for braces pain
This trial tests if a small device placed inside the mouth can ease pain from braces. You'll receive either real or fake treatment with the TENS device to see if it helps with soreness after adjustments.
San Francisco, CaliforniaAges 12 years+ - NCT06571006Enrolling by invitation
Music therapy for pain relief during spinal tap in babies
This study tests whether playing gentle music during a lumbar puncture (a spinal tap) can help lower a baby's pain. It's for newborn infants who need this procedure and have normal hearing.
ErzurumAges 1 month–1 month - NCT06579950Recruiting
Cool roofs and health study
This study tests whether a special cool roof coating can lower indoor temperatures and improve health. You may be eligible if you live in a home with a stable, safe roof.
OuagadougouAges 18 years+ - NCT06574152Recruiting
Light therapy for pain relief after dental root surgery
This trial tests whether a special light treatment, called photobiomodulation, can help reduce pain and speed up healing after a specific type of dental surgery on the root of a tooth. The surgery involves a small cut in the gum, and the light may help the gum recover faster.
Houston, TexasAges 18 years+ - NCT06567496Enrolling by invitation
Virtual reality for mental health and success in PT students
This study tests whether using virtual reality (VR) can help Physical Therapy students feel better mentally and do better in school. If you are a PT student at Belmont University and free from certain health issues that VR might affect, you may be able to join.
Nashville, TennesseeAges 18 years+
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Common questions
- Are there clinical trials for effectiveness?
- Yes. Clin2 currently lists 6,371 recruiting effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.