Clinical trials
Safety and Effectiveness clinical trials
Below are recruiting safety and effectiveness clinical trials, each written for real people, not researchers. We’re tracking 385 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07339943Recruiting
Focal laser ablation for intermediate-risk prostate cancer
This trial tests a new way to treat intermediate-risk prostate cancer using a targeted laser guided by micro-ultrasound and MRI. It aims to see if this less invasive approach is safe and effective for men who have not had prior prostate cancer treatments.
Toronto, OntarioAges 40–85 - NCT07098663RecruitingPhase 2
Study of MKP10241 for weight loss and diabetes control
This study tests an investigational drug called MKP10241 in healthy people, people with obesity, and people with type 2 diabetes. It aims to see how the drug affects blood sugar, weight, and overall safety. It may be an option if you have obesity or type 2 diabetes managed by diet and/or metformin.
Bayswater, VictoriaAges 18–60 - NCT07396675Recruiting
Operating room debriefing study for team effectiveness
This trial studies whether having structured team debriefings with the help of an Operating Room Black Box improves how well healthcare professionals work together and feel safe speaking up. It is for OR team members at three hospitals.
CopenhagenAges 18 years+ - NCT06398860Enrolling by invitation
Safety method trial for 24-hour care staff
This trial tests a new structured method for combining workplace safety and patient safety in 24-hour care settings. It may help if you work at least half-time in such a workplace.
FalunAges 18–70 - NCT07588880Recruiting
Tracking Odevixibat Safety and Outcomes in PFIC Patients
This study follows patients with PFIC (a rare liver disease affecting bile flow) who are taking or planning to take odevixibat (Bylvay), a medication that helps manage the condition. Researchers will track how well the medication works, any side effects, and long-term health outcomes in Chinese patients.
BeijingAges 6 months+ - NCT07448610RecruitingPhase 4
Real-world safety and effectiveness of gene therapy for spinal muscular atrophy
This study tracks how well the gene therapy ITVISMA works in everyday medical practice for people with spinal muscular atrophy (SMA). It aims to see if the treatment is safe and effective in a real-world setting.
New York, New YorkAges 2–100 - NCT06748937RecruitingPhase 2
Testing alpibectir plus ethionamide for new TB
This study tests an experimental oral TB drug called alpibectir given together with ethionamide for people with newly diagnosed lung TB. The goal is to see how well the combination works and if it is safe.
Cape Town, Western CapeAges 18–65 - NCT07185919Recruiting
Odevixibat (Bylvay) study for PFIC patients in South Korea
This study is tracking how well odevixibat (Bylvay) works and how safe it is for people with progressive familial intrahepatic cholestasis (PFIC) in South Korea. It is for patients who are already prescribed this medicine by their doctor, and it monitors their progress over time.
GyeongsangAges Any age - NCT06928753RecruitingPhase 4
Chikungunya vaccine study in Reunion and French Guiana
This study looks at how well the chikungunya vaccine works in real life, how safe it is, and how the body's immune system responds. It is for adults who are eligible for the vaccine according to French health guidelines.
CayenneAges 18 years+ - NCT02844751RecruitingPhase 2
Regenerative knee cell therapy for arthritis pain and swelling
This Phase 2 study tests a patient’s own (autologous) regenerative cell treatment to reduce knee pain and inflammation from osteoarthritis. It mainly looks at whether the treatment is safe and whether it can improve symptoms over time.
Grove City, PennsylvaniaAges 18–90 - NCT02844764RecruitingPhase 2
Cell therapy test for hip osteoarthritis pain and swelling
This trial tests an “autologous” regenerative cell treatment, meaning cells taken from you, to reduce hip osteoarthritis pain and inflammation. It checks safety first and looks for improvements in how you feel and move.
Grove City, PennsylvaniaAges 18–90 - NCT02844738RecruitingPhase 2
Cell therapy for shoulder osteoarthritis pain and inflammation
This trial tests a treatment using your own (autologous) regenerative cells to reduce pain and inflammation from shoulder osteoarthritis. It may help people with long-lasting shoulder pain, but you must meet several health and medication timing requirements.
Grove City, PennsylvaniaAges 18–90 - NCT06121843RecruitingPhase 1
Study of CAR-T cell therapy in combinations for multiple myeloma
This trial tests a new CAR-T cell therapy (called arlocabtagene autoleucel) combined with other drugs for multiple myeloma that has returned or stopped responding. It aims to find a safe and effective dose while tracking how well the treatment works.
Birmingham, AlabamaAges 18 years+ - NCT01402661Enrolling by invitation
Rheumatoid arthritis drug safety and effectiveness registry
This registry collects real-world information about people with rheumatoid arthritis (RA) to help doctors understand how RA medicines work and their safety. You may be able to join if you’re newly diagnosed or starting certain RA treatments and you’re willing to share consent and basic personal details.
Waltham, MassachusettsAges 18 years+ - NCT06282315RecruitingPhase 3
Safety of a new deworming pill for children in Ghana and Kenya
This trial tests how safe and effective a combined albendazole and ivermectin pill is for treating parasitic infections. It is for school-aged children in specific areas of Ghana and Kenya.
Accra, AccraAges 5–17 - NCT05702944RecruitingPhase 4
Skipping pre-surgery blood pressure medicine for certain adrenal tumors
This trial studies whether it is safe to skip a specific pre-surgery blood pressure medicine (alpha-blocker) for people with normal blood pressure who have a pheochromocytoma or paraganglioma in one adrenal gland. It aims to see if fewer pre-op meds can still prevent risky blood pressure surges during surgery.
SeoulAges 19–70 - NCT05113017Recruiting
Radiation after surgery for early lung cancer you can’t remove
This trial studies whether a focused form of radiation called SBRT can safely treat remaining lung cancer nodules after surgery. It may help people whose leftover tumor spots can’t be removed by more surgery, aiming to control the cancer while limiting side effects.
Changsha, HunanAges 18–75 - NCT07561892RecruitingPhase 4
Chemotherapy with or without silibinin for newly diagnosed blood cancer
This trial tests whether adding silibinin (a plant-based supplement) to standard chemotherapy drugs (daunorubicin or idarubicin) helps treat newly diagnosed acute myeloid leukemia (AML), a serious blood cancer. The goal is to see if this combination is more effective and safer than chemotherapy alone.
Fuzhou, FujianAges 18–65 - NCT07179848RecruitingPhase 1
Temporal interference brain stimulation safety study in healthy adults
This trial tests a new type of non-invasive brain stimulation that uses a weak electrical field to gently influence brain activity. It is designed for healthy adults to see if the procedure is safe and comfortable, and to gather information that could help develop future treatments for mental health conditions.
TaipeiAges 20–65 - NCT07592299Recruiting
New heat-free treatment for enlarged prostate symptoms
This study tests a new device that uses electrical pulses to treat an enlarged prostate without surgery or heat. It aims to relieve urinary symptoms like weak flow and frequent urination, and may be an option if you have moderate to severe symptoms.
Germantown, TennesseeAges 45 years+ - NCT07874581Recruiting
Study of MRG003 for small cell lung cancer that has returned
This study tests a new drug, MRG003, for people with a type of lung cancer called small cell lung cancer that has spread or come back after earlier treatment. The goal is to see if this drug can help shrink tumors or slow the cancer's growth.
ShanghaiAges 18 years+ - NCT07444450RecruitingPhase 3
Study of salanersen for babies with SMA previously treated with gene therapy
This study tests a new medicine called salanersen in babies who have already received gene therapy for SMA. It aims to see if adding salanersen is safe and effective.
Flower Mound, TexasAges birth–7 months - NCT07794761RecruitingPhase 3
Weekly injection for weight loss in adults with obesity in Japan
This study tests a once-weekly injection called berobenatide to see if it helps adults with obesity lose weight and improve related health problems like high blood pressure, high cholesterol, or blood sugar issues. It is for people living in Japan.
Chiba, ChibaAges 18 years+ - NCT07837973RecruitingPhase 2
Medicine to maintain weight loss after weight-loss shots
This study tests a new medicine called ALV-100 to see if it can help people who have already lost weight with a weight-loss injection or pill keep the weight off. You must be currently on a stable weight-loss medicine and have lost at least 10% of your body weight to join.
Birmingham, AlabamaAges 18–75
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Common questions
- Are there clinical trials for safety and effectiveness?
- Yes. Clin2 currently lists 385 recruiting safety and effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a safety and effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a safety and effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.