Clinical trials
Effectiveness clinical trials
Below are recruiting effectiveness clinical trials, each written for real people, not researchers. We’re tracking 6,827 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06860607RecruitingPhase 1
Environment and Alcohol: A Pilot Study
A pilot study exploring the interaction between environment and alcohol consumption in individuals with alcohol use disorder (AUD), using smartphone-based ecological momentary assessment (EMA).
Baltimore, MarylandAges 21–100 - NCT06930859Recruiting
Study of Ribociclib for HR+ HER2-negative breast cancer in Russia
This study looks at how well ribociclib works when given with hormone therapy after surgery for certain types of breast cancer. It aims to understand real-world benefits and safety for patients in Russia.
Sochi, Russian FederationAges 18–99 - NCT07332507RecruitingPhase 1
Testing teclistamab for recurrent plasmablastic lymphoma
This trial tests a new drug called teclistamab for people with plasmablastic lymphoma that has come back or not responded to standard treatments. The goal is to see if teclistamab can shrink tumors and control the disease.
Duarte, CaliforniaAges 18 years+ - NCT07391774RecruitingPhase 3
Hormone therapy with or without chemo for early breast cancer
This trial tests whether skipping chemotherapy and using only hormone therapy with a drug called ribociclib works as well as chemotherapy followed by hormone therapy with ribociclib for certain early breast cancers that have a low risk of coming back.
Jonesboro, ArkansasAges 18 years+ - NCT06820281RecruitingPhase 2
Tirzepatide for type 1 diabetes: a metabolism study
This study tests if tirzepatide, a medicine that helps lower blood sugar and manage weight, is safe and effective for people with type 1 diabetes who are overweight or have obesity. You must already use an automated insulin pump system.
Sydney, New South WalesAges 18–65 - NCT07671924RecruitingPhase 2
Testing nalbuphine extended-release for chronic cough
This trial tests whether an extended-release medication called nalbuphine can reduce coughing in people with chronic cough that hasn't improved with other treatments. You may be eligible if you've had a persistent cough for at least a year and have already tried treatments for conditions that could cause it.
AjaxAges 18 years+ - NCT07688213RecruitingPhase 2
Study of an investigational drug for early Alzheimer's disease
This trial tests an investigational injection for people in the early stages of Alzheimer's. It aims to see if the drug can safely slow down memory loss and brain changes.
The Villages, FloridaAges 55–85 - NCT07712640RecruitingPhase 1
Comparing two tablet forms of BGB-58067 and food effect
This study tests how two different tablet versions of the study drug BGB-58067 enter the body and how food affects the drug. Healthy volunteers take the drug to help understand the best way to give it in future trials.
Adelaide, South AustraliaAges 18–65 - NCT03884075RecruitingPhase 2
Semaglutide study for fatty liver and how sugar affects the liver
This Phase 2 study tests how semaglutide (a diabetes medication also used for weight) affects fatty liver and the liver’s response to sugar. It may help people with non-alcoholic fatty liver disease understand whether the drug improves liver fat and related changes.
Bethesda, MarylandAges 18–100 - NCT07271186RecruitingPhase 2
Study of a New Drug for Diabetic Kidney Disease
This study tests an investigational drug that blocks a protein called ANGPTL3, which may help protect the kidneys in people with type 2 diabetes and diabetic kidney disease. It aims to see if the drug can reduce kidney damage and improve overall health.
Huntsville, AlabamaAges 18–80 - NCT07488299Recruiting
Study of acid-reducing drug in pancreatic necrosis drainage
This trial tests whether giving a type of acid-reducing drug (called a PPI) affects the outcome of endoscopic drainage for walled-off pancreatic necrosis (WON). It aims to see if the drug helps or harms recovery.
Jinan, ShandongAges 18–80 - NCT06274749Recruiting
Urolithin A for blood sugar in adults 55+ with extra weight
This study tests if a natural supplement called Urolithin A can help improve how your body handles sugar (glucose) in healthy adults aged 55 and older who have a higher body weight. You would take a daily capsule and come in for tests including blood work, treadmill walks, and an MRI.
Baltimore, MarylandAges 55–100 - NCT07038746RecruitingPhase 1
Inhaled epinephrine for severe allergic reactions during tests or treatment
This trial tests if inhaled epinephrine can safely treat moderate to severe allergic reactions (grade 2 or higher) that can happen during allergy skin tests, oral food or drug challenges, or allergy shots. It is for people who have had such reactions in the past or are at risk and are planning to undergo one of these procedures.
Richmond, British ColumbiaAges 12 years+ - NCT07298421RecruitingPhase 3
Testing afimkibart for children with Crohn's disease
This trial tests a medicine called afimkibart for children with moderately to severely active Crohn's disease. It aims to see how well the drug works and how safe it is when used for both starting and ongoing treatment.
New York, New YorkAges 2–17 - NCT07146906RecruitingPhase 2
Study of zigakibart for IgA nephropathy
This trial tests a new drug called zigakibart for people with IgA nephropathy, a kidney disease. It aims to see if the drug can help reduce protein in the urine and protect kidney function.
Denver, ColoradoAges 18–100 - NCT07126444Recruiting
Exercise snacks for employee health and work performance
This study tests whether short, intense exercise breaks ('exercise snacks') during the workday can improve health and job performance over 12 weeks.
Kaohsiung CityAges Any age - NCT07754864Enrolling by invitation
Virtual reality education for first-time radiation therapy
This study tests whether using virtual reality (VR) before your first radiation therapy session can help reduce anxiety and improve your overall experience. You'll use a VR headset to see what treatment will be like, which may help you feel more prepared and at ease.
Muscat, Muḩāfaz̧at MasqaţAges 18 years+ - NCT07100106RecruitingPhase 1/Phase 2
Study of GDC-4198 alone or with giredestrant for advanced breast cancer
This trial tests a new treatment (GDC-4198) alone or with another drug (giredestrant) compared to a standard combination (abemaciclib and giredestrant) for people with advanced hormone receptor-positive, HER2-negative breast cancer that has progressed after previous treatments.
Tucson, ArizonaAges 18 years+ - NCT07749911Recruiting
Vaccine effectiveness study for malaria in young children
This study looks at how well the R21/Matrix-M malaria vaccine works in real-life settings for children under 5. If your child is eligible for the vaccine and has a fever, they may be able to join and help us understand the vaccine's impact.
Boromo, Boucle MouhounAges 5 months–5 years - NCT06837246Recruiting
Nutritional supplement study for cognitive health in adults
This study tests whether a nutritional supplement taken as 3 capsules daily for 12 weeks can improve cognitive function. It is designed for generally healthy adults who do not have certain medical conditions or take certain medications.
Addison, IllinoisAges 25–65 - NCT06816706Recruiting
Comparing two oxygen methods during breathing trials
This study compares two ways of giving oxygen (high-flow through the nose vs. a T-piece) to help patients come off a breathing machine safely. It aims to see which method works better during a test of your ability to breathe on your own.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06766604Recruiting
Super-GDF9 for egg maturation in women with PCOS
This study tests a protein called Super-GDF9 added to the lab process of maturing eggs from very small follicles. It may help women with PCOS produce more usable eggs for in vitro fertilization (IVF).
Ho Chi Minh CityAges 18–38 - NCT06763172RecruitingPhase 4
Caffeine's effect on learning in healthy adults
This study uses brain scans to see how caffeine affects the way we learn from rewards and punishments. You may be eligible if you are a healthy adult who drinks a moderate amount of caffeine daily.
Charlestown, MassachusettsAges 18–45 - NCT06759818Enrolling by invitation
Vagus nerve stimulation for heart protection after lung surgery in older adults
This trial tests if a gentle ear stimulation device can protect the heart after lung surgery in patients aged 60 and older. It is for those having a planned lung procedure (lobectomy, segmentectomy, or wedge resection) through small chest incisions.
Jiaxing, ZhejiangAges 60 years+
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Common questions
- Are there clinical trials for effectiveness?
- Yes. Clin2 currently lists 6,827 recruiting effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.