Clinical trials
Ehlers-Danlos Syndrome clinical trials
Below are recruiting ehlers-danlos syndrome clinical trials, each written for real people, not researchers. We’re tracking 16 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07464093Recruiting
Pilates for joint hypermobility pain
This trial tests if a special Pilates program can reduce pain in people with hypermobile Ehlers-Danlos syndrome or hypermobility spectrum disorder. You must have had pain for at least 3 months and be able to get on and off the floor on your own.
Chestnut Hill, MassachusettsAges 18 years+ - NCT05757960Enrolling by invitation
Physiotherapy program for jaw pain in hEDS
This study tests a tailored physical therapy (physiotherapy) approach for jaw pain caused by temporomandibular disorder (TMD) in people with hypermobile Ehlers-Danlos syndrome (hEDS). It may help reduce jaw muscle and joint pain and improve function.
MünsterAges 18 years+ - NCT07672210Recruiting
Pregnancy-related aortic dissection in China
This study is looking at cases of aortic dissection that happen during pregnancy or shortly after childbirth in China. It aims to understand how these events occur and how they can best be managed.
Shanghai, Shanghai MunicipalityAges 16–55 - NCT04133272Recruiting
Registry for Ehlers-Danlos syndrome patients and pregnancies
This study is a registry that collects information about people with Ehlers-Danlos syndrome, including unborn babies diagnosed before birth. It may help researchers learn more about the condition and improve care over time.
Bologna, Emilia-RomagnaAges Any age - NCT04310644Recruiting
Study of nerve and connective-tissue symptoms in EDS and autonomic issues
This study collects information about how the body’s automatic nerves (autonomic nerves) affect symptoms like fast heart rate on standing, fatigue, and related conditions in people with Ehlers-Danlos syndrome. It also enrolls healthy volunteers to compare results, which may help doctors understand these conditions better and improve care.
Aachen, North Rhine-WestphaliaAges 18–80 - NCT05212129Recruiting
Stimulation of the ear nerve to help gut symptoms
This study tests whether stimulating a nerve in the ear (called auricular vagal nerve stimulation) can improve upper gut symptoms in teens who may have hypermobile Ehlers-Danlos syndrome (hEDS) or hypermobile spectrum disorder (HSD). It also checks whether this treatment helps nerves that control the body (autonomic nervous system) and how well the gut moves.
Milwaukee, WisconsinAges 10–18 - NCT05432466RecruitingPhase 3
Celiprolol vs placebo for vascular Ehlers-Danlos heart vessel fragility
This Phase 3 study compares celiprolol (a blood vessel–related medicine) versus placebo to see which better reduces vascular risks in people with vascular Ehlers-Danlos syndrome. It requires confirmed COL3A1 genetic findings and specific imaging before starting.
Culver City, CaliforniaAges 15–64 - NCT05994664Recruiting
Heart Coherence Training for Vascular Ehlers-Danlos
This study tests whether a breathing and heart-rate training program (called Heart Coherence Training) can help people with Vascular Ehlers-Danlos syndrome feel better. It's done from home using your phone and a computer or tablet.
Houston, TexasAges 12–45 - NCT06539169Recruiting
Following people with rare diseases over time
This study follows people with rare diseases over time to learn more about how these conditions progress and how they are treated. Joining may help researchers understand your disease better and find better ways to care for others.
Los Altos, CaliforniaAges Any age - NCT06546137Recruiting
Registry for inherited heart conditions in Brazil
This study is building a national registry in Brazil to learn more about inherited heart conditions and improve care. If you have a family-related heart disease, you may be able to join and help advance cardiovascular healthcare.
Rio Branco, AcreAges Any age - NCT07151274Recruiting
Ehlers-Danlos syndrome and women's gynecological health
This study uses an online questionnaire to explore how Ehlers-Danlos syndrome (EDS) may affect gynecological health. It compares women with EDS to those without, to better understand any differences.
RouenAges 18–50 - NCT02050113Recruiting
Custom endograft repair for complex aortic aneurysms
This trial tests custom-made and doctor-modified grafts to treat complex bulges in the aorta (the body’s main artery) or the part going into the pelvis. It may help people who cannot use standard approved devices or who need treatment urgently because waiting is unsafe.
Worcester, MassachusettsAges 18 years+ - NCT07516496Recruiting
Understanding Body Chemistry in Vascular Ehlers-Danlos Syndrome
This study looks at how bodies with vascular Ehlers-Danlos syndrome (vEDS) process nutrients and energy differently. By comparing people with vEDS to healthy volunteers, researchers hope to find new ways to manage the condition better.
CambridgeAges 18–85 - NCT07565636Recruiting
Custom 3D-Printed Wrist Support for Ehlers-Danlos Syndrome
This trial tests a custom-made wrist brace designed with 3D printing technology to help stabilize loose, overly flexible wrists in people with Ehlers-Danlos syndrome. The goal is to see if this personalized support can improve wrist function and reduce pain or instability.
Lowell, MassachusettsAges 21 years+ - NCT07637084Recruiting
Light therapy for chronic pain and fatigue in Ehlers-Danlos Syndrome
This trial tests whether a non-invasive light therapy called photobiomodulation can reduce chronic pain and fatigue in people with hypermobile Ehlers-Danlos Syndrome (hEDS), a genetic condition affecting connective tissue. The light is applied to the skin and may help cells produce energy and reduce inflammation.
Boulogne-Billancourt, Île-de-France RegionAges 18 years+ - NCT07083713Enrolling by invitation
Group coaching for life goals with chronic conditions
This study tests if group coaching helps people with certain chronic conditions set and achieve life goals. You would join phone or video sessions with a coach and others like you.
Philadelphia, PennsylvaniaAges 18 years+
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Common questions
- Are there clinical trials for ehlers-danlos syndrome?
- Yes. Clin2 currently lists 16 recruiting ehlers-danlos syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ehlers-danlos syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ehlers-danlos syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.