Clinical trials
Emphysema or COPD clinical trials
Below are recruiting emphysema or copd clinical trials, each written for real people, not researchers. We’re tracking 432 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05042219Recruiting
How lung disease treatment may affect heart function
This study looks at how common long-term lung conditions and their treatments may change heart function. It uses heart imaging (an MRI) to see what’s happening, which could help doctors better monitor heart risks in people with lung disease.
AachenAges 18–99 - NCT05061368RecruitingPhase 2
Sildenafil by mouth to improve breathing in COPD
This Phase 2 trial tests whether sildenafil tablets can improve exercise ability, shortness of breath, and heart-lung function in people with COPD. It also compares against people without COPD to better understand how sildenafil affects breathing tests.
Edmonton, AlbertaAges 40–80 - NCT05193136Recruiting
Testing sleep and exercise effects on strength and thinking in lung disease
This trial studies whether improving sleep habits can help people with lung conditions like COPD or IPF maintain muscle strength and thinking (cognitive function). It may help by addressing sleep quality and related health factors, but eligibility depends on your current diagnoses and treatments.
Jōyō, KyotoAges 20 years+ - NCT05196698Recruiting
Home high-flow oxygen after COPD hospital flare
This study tests whether using a special oxygen device at home helps prevent another acute COPD flare after you’ve been hospitalized. It’s mainly for people with severe breathing problems who may need oxygen support long-term.
RouenAges 18–85 - NCT05235685Recruiting
Testing muscle fatigue during exercise in COPD and heart failure
This study looks at how tired your muscles get during a controlled cycling exercise test in people who have COPD, and—if applicable—heart failure at the same time. It may help researchers understand exercise limits and how to better support you with these conditions.
Échirolles, Auvergne-Rhône-AlpesAges 18 years+ - NCT05237505RecruitingPhase 2
Sleep apnea plus COPD study to check heart and breathing effects
This Phase 2 study looks at the cardiovascular (heart/blood vessel) effects of having both sleep apnea and COPD. It may help doctors better understand who is at risk and how to manage these breathing problems together.
La Jolla, CaliforniaAges 40–79 - NCT05265299RecruitingPhase 3
Testing the right aspirin dose for COPD symptoms
This Phase 3 trial studies which aspirin dose works best in people with COPD, with the goal of improving disease control. You may be asked to take aspirin and be monitored for safety, especially bleeding risk and heart/brain history.
Baltimore, MarylandAges 40–80 - NCT05306743Recruiting
Quality program for high-risk COPD, tested with primary care teams
This study looks at how well a quality-improvement program (called CONQUEST) helps people with higher-risk chronic lung disease (COPD) when delivered through primary care teams. It compares the program given right away versus usual care for a while, then the program later.
Denver, ColoradoAges 18 years+ - NCT05495698Recruiting
One or multiple inhalers plus app support for COPD
This trial looks at whether using one or more inhalers, together with a smartphone app, can help people manage chronic obstructive pulmonary disease (COPD) better. You may be eligible if you have COPD, need “triple therapy” (three medicine types), and can use the app and surveys.
Rotterdam, South HollandAges 40 years+ - NCT05553223Recruiting
Very small activity doses for COPD symptoms
This study tests whether “micro-doses” of physical activity (short, small amounts) can help people with COPD. It aims to see if these small activity bursts are safe and beneficial for people who have stable COPD.
Kelowna, British ColumbiaAges Any age - NCT05652439Recruiting
Assess heart and stroke events after starting triple COPD inhalers
This study looks at how often heart problems or stroke happen in people with COPD after they start a specific “triple therapy” inhaler. It may help doctors understand whether these inhalers change cardiovascular (heart) or cerebrovascular (stroke) risk.
LondonAges 40 years+ - NCT05671198Recruiting
Ultrasound test of breathing muscle function in severe COPD flare
This trial studies how well your diaphragm (the main breathing muscle) works during a severe COPD flare, using an ultrasound scan. It may help doctors better assess breathing muscle performance when COPD symptoms suddenly worsen.
Zwolle, OverijsselAges 18 years+ - NCT05696782RecruitingPhase 2
Durvalumab after chemoradiation for stage III lung cancer
This trial tests giving durvalumab (an immune therapy) soon after standard chemotherapy and radiation for stage II–III non-small cell lung cancer that cannot be removed by surgery. The goal is to see if this “quick start” approach improves outcomes compared with waiting longer to begin durvalumab.
Winston-Salem, North CarolinaAges 18 years+ - NCT05730088Recruiting
Helping COPD patients avoid hospital visits with home nursing support
This trial tests whether adding several nursing check-ins and coaching (using home oxygen and regular contact) can help people with severe COPD avoid going back to the hospital. It uses phone or internet tools to support care at home.
KonyaAges 18 years+ - NCT05743582Recruiting
Studying natural immunity in COPD and in healthy adults
This study looks at how the body’s “innate” (first-line) immune system works in people with COPD compared with healthy volunteers. It may help researchers understand COPD inflammation and how immune responses could be targeted in the future.
EdinburghAges 18–77 - NCT05772013RecruitingPhase 4
Checking azithromycin prevention for COPD flare-ups
This Phase 4 study looks at optimizing how people with COPD take azithromycin to reduce flare-ups (exacerbations). If you already take azithromycin regularly, the trial may test ways to improve how it’s used safely.
CambridgeAges 40 years+ - NCT05785026Recruiting
Menthol to reduce breathlessness in COPD and healthy adults
This trial tests whether menthol helps with breathlessness (dyspnea) during exercise. You may be asked to do breathing and exercise tests, and to use menthol under study supervision to see if symptoms improve.
LeuvenAges 18 years+ - NCT05831566RecruitingPhase 3
Digital coaching program for severe asthma control
This Phase 3 study tests whether an asthma care program with digital (phone-based) support helps people with severe asthma stay more stable and manage symptoms better. You may need to meet specific criteria for “severe, refractory” asthma and be willing to use a smartphone for monitoring and coaching.
Rotterdam, South HollandAges 18 years+ - NCT05896579Recruiting
Study heart function during rest and exercise in COPD
This study measures how well the right side of your heart works when you are resting and when you exercise, in people with chronic obstructive pulmonary disease (COPD). It may help researchers better understand COPD-related heart strain and guide future care.
Aurora, ColoradoAges 40 years+ - NCT05903001Recruiting
Breathing muscle testing to help track lung disease
This study checks whether measurements of your breathing muscle (the diaphragm) can act as a useful “biomarker” to track lung disease. You might be asked to do breathing tests and follow study instructions, and your results may help researchers better monitor COPD, asthma, fibrosis, or pulmonary hypertension.
Aachen, North Rhine-WestphaliaAges 18 years+ - NCT05926713Recruiting
Diet supplement plus exercise for muscle loss with lung disease
This trial studies whether adding a dietary supplement to exercise can improve muscle strength in people with muscle loss (sarcopenia) who also have lung disease such as COPD or ILD. It may help you build strength and function without needing urgent hospital care.
TaichungAges Any age - NCT05934565Recruiting
Using mindfulness coaching to help people move more
This trial studies a program that uses mindfulness coaching to help people with chronic lung disease (COPD) and/or heart failure (HF) be more physically active. You may benefit if you can safely start exercising and track your steps using a Fitbit.
Boston, MassachusettsAges 40 years+ - NCT05937854RecruitingPhase 2
Tadalafil to help breathing in COPD with pulmonary hypertension
This Phase 2 study tests whether tadalafil can improve breathlessness in people with COPD and pulmonary hypertension (high blood pressure in the lungs). It may help you breathe more easily if your symptoms are driven by this specific lung circulation problem.
Aurora, ColoradoAges 35–89 - NCT06001645Recruiting
Lung biomarkers and air leaks in severe lung injury
This study looks for markers in the blood and signs of air trapped in the lung tissue of people with acute respiratory distress syndrome (ARDS). It uses CT scans to understand why air leaks happen and if certain lab tests can predict them.
CagliariAges 18 years+
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Common questions
- Are there clinical trials for emphysema or copd?
- Yes. Clin2 currently lists 432 recruiting emphysema or copd studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a emphysema or copd trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a emphysema or copd trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.