Clinical trials
Emphysema or COPD clinical trials
Below are recruiting emphysema or copd clinical trials, each written for real people, not researchers. We’re tracking 432 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05879211Enrolling by invitation
Care learning lab for Duke Health patients
This trial is a “learning laboratory” that studies how best to provide goal-focused care. It may help improve care experiences for Duke Health patients, based on what the study learns.
Durham, North CarolinaAges 18 years+ - NCT05743582Recruiting
Studying natural immunity in COPD and in healthy adults
This study looks at how the body’s “innate” (first-line) immune system works in people with COPD compared with healthy volunteers. It may help researchers understand COPD inflammation and how immune responses could be targeted in the future.
EdinburghAges 18–77 - NCT05727852Enrolling by invitation
Breath and heart tests to study lung disease stiffness
This study uses breath analysis and heart/electrical heart testing to look at how stiff the arteries are in people with long-term lung conditions. It may help researchers better understand lung disease effects on the cardiovascular system.
MoscowAges 18 years+ - NCT05696782RecruitingPhase 2
Durvalumab after chemoradiation for stage III lung cancer
This trial tests giving durvalumab (an immune therapy) soon after standard chemotherapy and radiation for stage II–III non-small cell lung cancer that cannot be removed by surgery. The goal is to see if this “quick start” approach improves outcomes compared with waiting longer to begin durvalumab.
Charlotte, North CarolinaAges 18 years+ - NCT05443321Enrolling by invitation
Health information sharing during hospital transfers
This trial studies whether sharing patients’ health information between hospitals during transfers can improve outcomes. You may be included if you are moved from a specific partner hospital to Brigham and Women’s Hospital and admitted to certain hospital units.
Boston, MassachusettsAges 18 years+ - NCT05339048Enrolling by invitation
Study of adults from Colombia’s Caribbean coast
This study follows adults who were born or are from Colombia’s Caribbean coast. The goal is to learn about health patterns in this community, but you would not be able to join if you meet certain medical or disability-related criteria.
Cartagena, Departamento de BolívarAges 18–80 - NCT05265299RecruitingPhase 3
Testing the right aspirin dose for COPD symptoms
This Phase 3 trial studies which aspirin dose works best in people with COPD, with the goal of improving disease control. You may be asked to take aspirin and be monitored for safety, especially bleeding risk and heart/brain history.
Baltimore, MarylandAges 40–80 - NCT05237505RecruitingPhase 2
Sleep apnea plus COPD study to check heart and breathing effects
This Phase 2 study looks at the cardiovascular (heart/blood vessel) effects of having both sleep apnea and COPD. It may help doctors better understand who is at risk and how to manage these breathing problems together.
La Jolla, CaliforniaAges 40–79 - NCT05181826Recruiting
Blood collection study for cancer and benign diseases
This study collects blood samples from people with different health conditions (cancer, diabetes, liver disease, etc.) and from healthy volunteers. The goal is to find markers in the blood that could help detect or monitor diseases.
Redondo Beach, CaliforniaAges 18 years+ - NCT05196698Recruiting
Home high-flow oxygen after COPD hospital flare
This study tests whether using a special oxygen device at home helps prevent another acute COPD flare after you’ve been hospitalized. It’s mainly for people with severe breathing problems who may need oxygen support long-term.
RouenAges 18–85 - NCT05163600Recruiting
Exercise with or without blood flow restriction for health
This study compares how your heart and lungs respond to two different types of exercise: one with a special cuff that slightly limits blood flow and one without. It may help if you are healthy or have COPD.
Zurich, Canton of ZurichAges 18–90 - NCT05012033Recruiting
Study how high-dose steroids move through the body
This study measures blood levels of high-dose steroid medicines (prednisolone or related steroids) to understand how the body processes them in different real-life situations. It may help improve how steroids are dosed and monitored for people needing short-term or longer-term anti-inflammatory treatment.
LondonAges 18–75 - NCT05061368RecruitingPhase 2
Sildenafil by mouth to improve breathing in COPD
This Phase 2 trial tests whether sildenafil tablets can improve exercise ability, shortness of breath, and heart-lung function in people with COPD. It also compares against people without COPD to better understand how sildenafil affects breathing tests.
Edmonton, AlbertaAges 40–80 - NCT04849806Recruiting
Testing whether heart nerve signals predict COPD symptoms
This study looks at “sympathetic nerve activity” (signals from the nervous system that affect the heart) in adults with chronic obstructive pulmonary disease (COPD). The goal is to see whether these measurements can help predict what happens to people with COPD.
AachenAges 18 years+ - NCT04778046RecruitingPhase 2
Study lung pressure treatment for people waiting for transplant
This Phase 2 trial is for adults with pulmonary hypertension who are on the lung transplant waiting list at Duke. It aims to test whether the study treatment can improve lung pressure and related health outcomes, while using things like MRI to monitor changes.
Durham, North CarolinaAges 18 years+ - NCT04624490RecruitingPhase 1
Lung function MRI using a special gas in volunteers
This Phase 1 study tests a lung scan that uses a special gas and MRI to measure how well your lungs work. It includes healthy volunteers and people with lung disease to see how well the scan works and how safe it is.
Kansas City, KansasAges 3 years+ - NCT04302272Recruiting
Study for people with severe emphysema and limited lung collateral airflow
This registry study follows adults with severe emphysema who have shortness of breath and low natural “backup” airflow between parts of the lung. It may help better understand how a specific FDA-approved treatment works for the right patients over time.
Phoenix, ArizonaAges 18 years+ - NCT04179981Recruiting
CPAP treatment effects in older COPD and sleep apnea patients
This study looks at whether using positive airway pressure (often called CPAP) improves health outcomes in older adults who have both COPD and obstructive sleep apnea. It may help find ways to reduce symptoms and complications from “overlap” breathing problems.
Detroit, MichiganAges 60 years+ - NCT04253964RecruitingPhase 2
Chemotherapy plus immunotherapy for advanced lung cancer
This study tests a combination of chemotherapy and immunotherapy in people with advanced non-small cell lung cancer that has spread or cannot be removed with surgery. The goal is to see how well this treatment works in patients with different levels of daily activity.
Charlotte, North CarolinaAges 18 years+ - NCT03799354Recruiting
Strength training study for people with COPD
This trial tests whether a maximal strength training program can help people with COPD who are stable. It is looking at people with moderate-to-severe airflow limitation and excludes several other lung and health problems.
Lumezzane, BresciaAges 50–80 - NCT03524222Recruiting
Home hospital care for adults after sudden illness
This trial tests whether certain adults can safely receive hospital-level care at home instead of staying in the hospital, using a home care team. It may help you recover in your own home if your condition fits their plan and you have support at home.
Boston, MassachusettsAges 18 years+ - NCT02777879Recruiting
Study gut-like lung bacteria and inflammation in early COPD
This study looks at the lung’s tiny bacteria (microbiome) and inflammation in people with early COPD who have a smoking history. It compares them with smokers who have normal breathing tests, to better understand what may drive COPD early on.
New York, New YorkAges 18–70 - NCT03249428Enrolling by invitation
Cytisine vs nicotine patches for quitting smoking
This study compares cytisine (an aid to reduce cravings) with nicotine replacement therapy (like patches or gum) to help people quit tobacco/nicotine. It also looks at whether the two options work for people facing higher barriers like low income or housing insecurity.
Ottawa, OntarioAges 18 years+ - NCT02796937Enrolling by invitationPhase 3
Long-term safety study of a blood protein for Alpha-1
This study checks how safe a prescribed blood protein medicine (alpha-1 proteinase inhibitor) is over the long term in people with Alpha-1 antitrypsin deficiency. You may join if you already finished an earlier study or if your lung function has been declining.
Phoenix, ArizonaAges 20–72
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Common questions
- Are there clinical trials for emphysema or copd?
- Yes. Clin2 currently lists 432 recruiting emphysema or copd studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a emphysema or copd trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a emphysema or copd trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.