Clinical trials
Emphysema clinical trials
Below are recruiting emphysema clinical trials, each written for real people, not researchers. We’re tracking 41 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03263130Recruiting
Study breathing limits in overlap asthma-COPD
This trial looks at what causes breathing to become harder when you blow air out in people with asthma-COPD overlap, and in some people with emphysema or bronchiectasis. It may help researchers better understand your condition’s breathing problem and how to target it.
Lakewood, CaliforniaAges 30 years+ - NCT06655428Recruiting
A new treatment for severe emphysema using heat and liquid
This trial tests a procedure called Endobronchial Thermal Liquid Ablation (ETLA) that uses heated liquid to treat severe emphysema. It is for people with COPD who have very low lung function and shortness of breath, and who have not been able to get relief from other treatments.
Vienna, AustriaAges 40 years+ - NCT07119229Recruiting
New implant study for severe emphysema
This trial tests a new implant for people with severe emphysema. It aims to see if the implant can help you breathe easier and walk farther.
San Francisco, CaliforniaAges 22 years+ - NCT06533371Recruiting
Ultrasound for emphysema in COPD and lung cancer
This study uses ultrasound (a safe, painless sound wave test) to check for emphysema (damaged air sacs in the lungs) in people with COPD or those being screened for lung cancer. It aims to see if ultrasound can replace the need for CT scans.
Acquaviva delle FontiAges 18 years+ - NCT06035120Recruiting
Sealing damaged lung parts in severe emphysema
This trial tests a new treatment called AeriSeal to seal off damaged parts of the lung in people with severe emphysema. It aims to help you breathe better by reducing the amount of air trapped in your lungs.
Phoenix, ArizonaAges 40–80 - NCT06163131Recruiting
How endobronchial valves affect diaphragm movement in emphysema
This trial measures how well your diaphragm (the main breathing muscle) moves after you get endobronchial valves (tiny one-way valves in your airways) for emphysema. It helps doctors see if the valves improve your breathing muscle function.
AarhusAges 18 years+ - NCT04537182Recruiting
Surgery versus bronchoscopy for severe emphysema
This study compares two ways to reduce lung “overinflation” in people with severe emphysema: surgery (LVRS) or a bronchoscopy procedure (BLVR). It aims to see which approach works best and is safest for eligible patients.
ViennaAges 30–80 - NCT07715617Recruiting
Creating a prediction score for lung transplant or death in Alpha-1 Antitrypsin Deficiency
This study is creating a simple scoring system to predict who with Alpha-1 Antitrypsin Deficiency-related emphysema might need a lung transplant or die from the disease. Your medical records from 2010–2025 will help build this tool, with no extra tests or visits required.
BronAges 18 years+ - NCT06690385Recruiting
Lung cancer screening for people with COPD or emphysema
This trial offers a lung cancer screening program using a low-dose CT scan for people who have COPD or emphysema and a history of heavy smoking. The goal is to catch lung cancer early, when it's more treatable.
MadridAges 55–75 - NCT07097896Recruiting
Lung valve treatment for emphysema
This trial tests a small silicone valve placed in your airways to help you breathe better if you have emphysema. It may be an option if you have severe breathing problems and are not getting enough relief from medicine alone.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07086339Recruiting
Artificial bronchus implant for severe emphysema
This trial tests an implantable artificial bronchus to help people with severe emphysema breathe easier. It's for those who have stable COPD, can walk 100–400 meters in 6 minutes, and haven't smoked for at least 4 months.
LimogesAges 22 years+ - NCT05825261Recruiting
Testing new blood or breathing markers for emphysema detection
This study looks for new measurable signs (“markers”) that can help detect emphysema earlier and more accurately. You may be asked to have breathing measurements and complete tasks if you have COPD and have had a recent chest CT scan.
Maastricht, LimburgAges 18 years+ - NCT05717192Recruiting
Bronchoscopy treatment to shrink severe emphysema using heat
This trial studies a bronchoscopy procedure that uses heat (thermoablation) to reduce over-inflated lung tissue in people with severe emphysema. If you qualify, it aims to improve breathing and walking ability after trying standard treatments first.
BerlinAges 40–75 - NCT06152107Recruiting
BTVA Treatment for Severe Emphysema Study
This study tests a new bronchoscopic treatment called BTVA for people with severe emphysema. It uses heat to shrink damaged parts of the lung to improve breathing.
Zhengzhou, HenanAges 18 years+ - NCT06332885Recruiting
Zephyr Valve study for severe COPD patients in Japan
This study is tracking the real-world use of the Zephyr Valve, a device that helps people with severe COPD breathe easier. It will check if the valve is safe and works well for people in Japan who have been chosen for this treatment by their doctor.
AichiAges 18 years+ - NCT04801108Recruiting
Lung valve treatment for emphysema with specific lung anatomy
This trial tests a one-way lung valve system to reduce over-inflated lung areas in people with emphysema. It’s aimed at patients whose lung scans suggest they may benefit from “fissure completion” to improve airflow.
Boston, MassachusettsAges 40–75 - NCT00307281Recruiting
Emphysema and COPD patient registry with sample storage
This study enrolls people who have emphysema/COPD into a research registry and collects health information and biological samples. It may help researchers understand the disease better and improve future treatments.
Pittsburgh, PennsylvaniaAges 21 years+ - NCT04200079Recruiting
Long-term follow-up study for people with COPD
This study follows people with COPD over time to better understand their lung health and how it changes. It may help researchers and doctors learn what factors affect breathing and long-term outcomes.
Kingston, OntarioAges 40–85 - NCT02803242Recruiting
Patient research network for people with lung symptoms
This trial enrolls adults to help build a patient-powered research network for chronic lung disease. If you join, you’ll likely be asked to complete surveys or provide information to help researchers learn how symptoms and health outcomes change over time.
Washington D.C., District of ColumbiaAges 18 years+ - NCT02815683Recruiting
Bronchoscopy treatment with one-way lung valves
This study looks at outcomes from placing one-way valves in the lungs using a camera procedure through the airways (bronchoscopy). If you’re already planned for this type of valve treatment, you may be able to join to help researchers learn how it works.
GroningenAges Any age - NCT04214587Recruiting
Study of removed lung valves after treatment
This study looks at lung tissue taken out after a treatment that places a one-way lung valve to help breathing. They want to learn how the valve affects the airway and lung over time.
GroningenAges Any age - NCT07731958Recruiting
One vs both lungs surgery for emphysema
This trial compares removing damaged parts of one lung versus both lungs to help people with severe COPD breathe better. It looks at which approach gives better results with fewer risks.
CopenhagenAges 18–75 - NCT04761393Recruiting
Testing a lung protein in COPD sputum samples
This study looks at a lung protein called MMP12 in sputum (mucus) to better understand COPD. It may help researchers learn which COPD changes are linked to disease severity and lung damage.
Hamilton, OntarioAges 40–85 - NCT07597187Recruiting
Analyzing lung tissue samples to improve chronic lung disease diagnosis
This study uses a new imaging technology called LIBS to examine lung tissue samples that were already removed as part of your regular care. The goal is to see if this method can help doctors better understand and diagnose chronic lung diseases like interstitial lung disease, sarcoidosis, or emphysema.
GrenobleAges 18 years+
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Emphysema trials by city
Studies with a site in or near these metro areas.
Emphysema trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for emphysema?
- Yes. Clin2 currently lists 41 recruiting emphysema studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a emphysema trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a emphysema trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.