Clinical trials
End Stage Chronic Renal Failure clinical trials
Below are recruiting end stage chronic renal failure clinical trials, each written for real people, not researchers. We’re tracking 54 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07348237RecruitingPhase 1
Testing a new kidney disease drug in patients with kidney failure
This trial tests the safety of a new medicine (MK-2828) in people with advanced kidney disease or on dialysis, and compares them to healthy volunteers. The goal is to understand how the drug works in the body and if it's safe for these patients.
Miami Lakes, FloridaAges 24–85 - NCT07705269Recruiting
High-rate fluid removal for fluid overload in dialysis patients
This trial tests whether a faster rate of fluid removal during dialysis can help hospitalized patients with end-stage kidney disease who have severe fluid buildup. It aims to reduce fluid congestion and improve outcomes.
Monterrey, Nuevo LeónAges 18 years+ - NCT03778944Recruiting
Improving kidney graft function during donor kidney surgery
This study looks at ways to help a donated kidney work better after transplant. It is intended for people who are receiving a living-donor kidney transplant due to kidney failure.
CairoAges 18–60 - NCT04671771Recruiting
Testing a new graft for hemodialysis access in kidney failure
This study tests whether an “AV graft” implant works safely and well for people with end-stage kidney disease who need hemodialysis. It may help your dialysis access last and work better, compared with current expectations for AV grafts.
Phoenix, ArizonaAges 18–90 - NCT04768322Recruiting
LVAD versus standard heart failure medicines in advanced patients
This trial compares an LVAD device (a pump placed in the chest) plus medicines versus medicines alone for people with advanced, end-stage heart failure. It aims to see which approach works better to help patients live and stay out of the hospital.
BesançonAges 18 years+ - NCT05092373RecruitingPhase 1
Tumor treating device plus targeted or immune drugs for advanced cancers
This Phase 1 study tests whether a tumor treating fields device works better when added to standard cancer drugs. It may help people with advanced solid tumors in the chest or belly, especially when standard treatment didn’t work or can’t be tolerated.
Houston, TexasAges 18 years+ - NCT05410275RecruitingPhase 3
Low-dose rivaroxaban for dialysis patients without blood thinners
This study tests whether a lower dose of the blood thinner rivaroxaban is safe for people with kidney failure on dialysis who do not already need blood thinners. The goal is to find a way to prevent blood clots and strokes with less risk of bleeding.
ToursAges 18 years+ - NCT05726526Recruiting
Phone app monitoring to help people with advanced kidney disease
This study tests a phone app (with check-ins on things like blood pressure and weight) to help prevent complications in people with advanced chronic kidney disease. You may be a good match if you’re high risk and can actively measure and share your health data with a kidney care team.
Winnipeg, ManitobaAges 18 years+ - NCT06001827Recruiting
Study of a wrap to help new dialysis access points heal
This trial tests a special wrap placed around a new arm access point for dialysis (called an AV fistula) to see if it helps the access stay healthy and work better. It is for people who need a new AV fistula for kidney dialysis.
Bullhead City, ArizonaAges 18 years+ - NCT06056102RecruitingPhase 1
CAR-T cell therapy to help highly sensitized kidney transplant patients
This trial tests whether a special immune cell treatment (CAR-T cells) can lower the antibodies that make it very hard for you to receive a kidney transplant. If it works, you might become eligible for a transplant sooner.
Boston, MassachusettsAges 18–65 - NCT06224140Recruiting
Dialysis without heparin: a safety study
This study tests whether dialysis can be done safely without using heparin (a blood thinner) in people with end-stage kidney disease. If successful, it could reduce the need for blood-thinning medications and their associated risks.
Marseille, Bouches du RhôneAges 18 years+ - NCT06249932RecruitingPhase 4
Empagliflozin for heart failure and end-stage kidney disease
This trial tests whether empagliflozin, a medication for heart failure, can help people who also have end-stage kidney disease and are on dialysis. It aims to see if the drug improves heart function in this group.
Hsinchu, TaiwanAges 20 years+ - NCT06249945RecruitingPhase 4
Empagliflozin for heart failure with preserved ejection fraction and dialysis
This trial tests whether a medicine called empagliflozin (used for diabetes and heart failure) can help people with both heart failure (with preserved pumping ability) and end-stage kidney disease who are on dialysis. The study looks at how the drug affects heart function and overall well-being.
HsinchuAges 20 years+ - NCT06314503Recruiting
Safety study of a new peritoneal dialysis device for kidney patients
This trial tests a new device called WEAKID for people on peritoneal dialysis. It aims to see if the device is safe to use. Participants must have been on PD for at least 3 months and have no recent infections or catheter problems.
Modena, ModenaAges 18 years+ - NCT06660277Recruiting
Dialysis with expanded solute removal study
This trial tests a special dialysis filter (Elisio HX) that removes more waste products from the blood. It aims to see if this approach improves health outcomes for people on regular in-center hemodialysis.
London, OntarioAges 45 years+ - NCT06750575Recruiting
Study of furosemide on toxin removal in chronic kidney disease
This study tests whether the water pill furosemide can help remove certain toxins from the blood in people with chronic kidney disease (CKD stages 3-5) who are starting this medicine as part of their regular care.
Utrecht, UtrechtAges 18 years+ - NCT06903559RecruitingPhase 1/Phase 2
Roxadustat for heart and nutrition in dialysis patients
This study tests whether roxadustat can help improve heart health, nutrition, and reduce inflammation in people on hemodialysis. It may offer a new treatment option for anemia related to kidney disease.
Al Mansurah, DakahliyaAges 18 years+ - NCT06917950RecruitingPhase 1/Phase 2
Roxadustat for bone and brain health in dialysis patients
This study tests whether roxadustat, a medicine for anemia, can also help with bone problems and mood or thinking issues in people on hemodialysis.
Al Mansurah, DakahliyaAges 18 years+ - NCT07053462RecruitingPhase 1/Phase 2
Gene-edited kidney transplant to lower rejection risk
This trial tests a specially edited donor kidney designed to reduce the chance of rejection, especially for people with high sensitivity to donor kidneys. If it works, it could make more kidneys available for those who have a hard time finding a match.
Beijing, ChangpingAges 16–85 - NCT07385651Recruiting
Cool storage for donated kidneys
This trial compares storing donated kidneys at 10 degrees Celsius (a cooler temperature) instead of the usual ice storage. It tests if this might help the kidney stay healthier before transplant.
Nashville, TennesseeAges 18 years+ - NCT02699736Enrolling by invitation
HIV and hepatitis C study in European adults
This study follows people living with HIV who also have hepatitis C antibodies, to better understand how HIV and hepatitis C affect health over time. You may be able to join if you meet the age and enrollment requirements, even if your hepatitis C virus level is currently undetectable.
Buenos AiresAges 16 years+ - NCT07491042Recruiting
A study of SGLT2 inhibitors for people on peritoneal dialysis
This study tests whether a type of diabetes medicine called SGLT2 inhibitors (which help lower blood sugar and protect the kidneys) can benefit people who are on chronic peritoneal dialysis. You may be able to join if you are 13 or older, have some urine output, and do not have certain other health issues.
NizwaAges 13 years+ - NCT07535320Recruiting
What Dialysis Treatment Do Patients Prefer?
This research study asks patients with advanced kidney disease about their preferences for different dialysis treatment options before starting treatment. Your feedback helps doctors understand what matters most to patients when choosing how to manage their kidney disease.
CaenAges 18 years+ - NCT07626710Recruiting
How Heart Valve Replacement Affects Kidney Function
This study looks at whether a minimally invasive heart valve procedure (TAVI) affects how well your kidneys work. Researchers will track your kidney function before and after the procedure using blood tests to understand any changes.
Roma, RMAges 18 years+
Hear when a new End Stage Chronic Renal Failure trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for end stage chronic renal failure?
- Yes. Clin2 currently lists 54 recruiting end stage chronic renal failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a end stage chronic renal failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a end stage chronic renal failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.