Clinical trials · North Carolina
End Stage Kidney Disease clinical trials in North Carolina
We’re tracking 14 recruiting end stage kidney disease studies with a site in North Carolina — including Phase 1/Phase 2, Phase 2, Phase 2/Phase 3 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in North Carolina
- NCT06749457RecruitingPhase 1/Phase 2
Study of a new drug for healthy adults and kidney patients on dialysis
This trial tests a new drug called AZD7760 in two groups: healthy adults (Phase I) and adults with end-stage kidney disease who are on hemodialysis through a central venous catheter (Phase IIa). The goal is to see how safe the drug is and how the body processes it. This could lead to a new treatment option for people on dialysis.
Kinston, North CarolinaAges 18–55 - NCT05485961RecruitingPhase 2/Phase 3
Clazakizumab for kidney failure patients on dialysis
This study tests an experimental drug called clazakizumab (CSL300) to see if it can reduce inflammation and lower the risk of heart problems in people with kidney failure who are on dialysis. It may help if you have diabetes or heart disease and have high inflammation levels.
Charlotte, North CarolinaAges 18 years+ - NCT05828823Recruiting
Two-times-a-week dialysis for new patients
This study tests whether starting dialysis at twice a week, instead of the usual three times, is safe and effective for people who still have some kidney function. If the kidneys still make urine and clear waste, being on dialysis less often may maintain that function longer.
Chapel Hill, North CarolinaAges 18 years+ - NCT04160507Recruiting
Biobank study collecting samples about kidney health in Black adults
This study builds a research “bank” (biorepository) of blood and other samples from Black adults with different stages of kidney health, including people with kidney disease and people without known kidney disease. It may help researchers better understand kidney risk and causes over time.
Durham, North CarolinaAges 18 years+ - NCT04634916Recruiting
Check how a dialysis fistula device performs in real life
This study monitors how well the BD WavelinQ endoAVF device works after routine clinical use. It may help people who need a dialysis access fistula by sharing real-world safety and performance data.
Raleigh, North CarolinaAges 18 years+ - NCT04671771Recruiting
Testing a new graft for hemodialysis access in kidney failure
This study tests whether an “AV graft” implant works safely and well for people with end-stage kidney disease who need hemodialysis. It may help your dialysis access last and work better, compared with current expectations for AV grafts.
Charlotte, North CarolinaAges 18–90 - NCT06001827Recruiting
Study of a wrap to help new dialysis access points heal
This trial tests a special wrap placed around a new arm access point for dialysis (called an AV fistula) to see if it helps the access stay healthy and work better. It is for people who need a new AV fistula for kidney dialysis.
Charlotte, North CarolinaAges 18 years+ - NCT07033117Recruiting
Improving kidney transplant access with RaDIANT
This trial tests if a special program helps dialysis centers refer more people to large transplant centers for a kidney transplant.
Durham, North CarolinaAges 18–80 - NCT07153939Recruiting
Study of a new device to create dialysis access
This trial tests a new device called the Velocity pAVF System that creates a connection between a vein and artery in your arm for hemodialysis. If you need dialysis now or within the next 6 months, this could be a new option for you.
Charlotte, North CarolinaAges 18–80 - NCT07237295Recruiting
CommunityRx Kidney Health Support Program
This study is testing a program called CommunityRx that gives kidney health information and resources to people with chronic kidney disease. It aims to help you better manage your condition between doctor visits.
Beulaville, North CarolinaAges 18 years+ - NCT05312879RecruitingPhase 2/Phase 3
Test drug VX-147 for APOL1-related protein in urine kidney disease
This trial studies whether VX-147 can improve kidney disease caused by an APOL1 gene change, which often leads to protein leaking into the urine. It includes both adults and children and focuses on safety and effectiveness over time.
Cary, North CarolinaAges 10–65 - NCT05832229RecruitingPhase 2
Studying rosuvastatin to slow liver scarring in cirrhosis
This Phase 2 trial tests whether rosuvastatin (a cholesterol-lowering medicine) can improve how well the liver functions and slow worsening scarring in people with cirrhosis. It also checks for side effects and safety.
Durham, North CarolinaAges 18–75 - NCT07221188RecruitingPhase 3
Efimosfermin alfa for liver scarring in MASH
This study tests an investigational drug called efimosfermin alfa to see if it is safe and tolerable for people who have liver scarring (F2 or F3 stage) from a condition called MASH. The goal is to find out if the drug can help without causing serious side effects.
Morehead City, North CarolinaAges 18–75 - NCT07221227RecruitingPhase 3
Testing a new drug for MASH with moderate scarring
This trial tests a new medicine called Efimosfermin Alfa for people with MASH (a fatty liver disease) and moderate liver scarring. It aims to see if the medicine can improve the liver condition.
Fayetteville, North CarolinaAges 18–75
End Stage Kidney Disease trials by city in North Carolina
Where these studies are running in North Carolina
Institutions with a site for the recruiting end stage kidney disease studies listed above.
- Duke University Medical Center · 3 studies
- Surgical Specialists of Charlotte · 3 studies
- Eastern Nephrology Associates · 2 studies
- GSK Investigational Site · 2 studies
- Metrolina Nephrology Associates, PA · 2 studies
- North Carolina Nephrology · 2 studies
- WakeMed Health & Hospitals · 2 studies
- Atrium Health Wake Forest Baptist Medical Center (Wake Forest Baptist)
What taking part in a end stage kidney disease study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
End Stage Kidney Disease trials in other states
Common questions
- Are there end stage kidney disease clinical trials in North Carolina?
- Yes. We're currently tracking 14 recruiting end stage kidney disease studies with a site in North Carolina, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a end stage kidney disease study in North Carolina?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in North Carolina to take part?
- Not necessarily. These studies have a site in North Carolina, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a end stage kidney disease trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New end stage kidney disease studies open in North Carolina regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.