Clinical trials
Endometrial clinical trials
Below are recruiting endometrial clinical trials, each written for real people, not researchers. We’re tracking 356 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07377734RecruitingPhase 2
Collagen injection before fertility-sparing therapy for early endometrial cancer
This trial tests whether an injection of type III collagen into the uterus before standard progestin therapy can help preserve fertility in women with very early endometrial cancer or atypical hyperplasia. It is designed for women who want to keep the option of having children.
BeijingAges 18–45 - NCT07368205Recruiting
Risk assessment before surgery for endometrial cancer
This trial looks at better ways to predict how aggressive your endometrial cancer is before surgery, so doctors can decide if they need to check your lymph nodes. It may help tailor your treatment to avoid unnecessary procedures.
Hradec KrálovéAges 18 years+ - NCT07318324RecruitingPhase 1
Study of three drugs for advanced endometrial cancer with RAS mutations
This trial tests a combination of three targeted drugs (avutometinib, defactinib, and everolimus) for people whose endometrial cancer has a specific change in the RAS pathway and has not responded to other treatments. The goal is to see if this drug combo can shrink tumors or slow their growth.
Houston, TexasAges 18 years+ - NCT07318415Recruiting
Ultrasound imaging study for endometrial cancer
This study tests a new ultrasound technique (multiparametric ultrasound) to see if it can better image endometrial cancer after surgery. It is for people who have had their cancer removed and will receive radiation therapy.
Basking Ridge, New JerseyAges 18 years+ - NCT07319429RecruitingPhase 2/Phase 3
Fertility-sparing treatment for endometrial cancer based on molecular type
This trial tests a tailored approach to preserve fertility in women with early-stage endometrial cancer, using medications like hormones and immunotherapy based on the tumor's molecular subtype. It aims to avoid hysterectomy and keep the uterus intact.
Shanghai, Shanghai MunicipalityAges 18–45 - NCT07286331RecruitingPhase 3
New drug vs chemo for advanced endometrial cancer
This trial tests a new drug (mocertatug rezetecan) compared to standard chemotherapy for people with endometrial cancer that has progressed after platinum-based chemo and immunotherapy. It may help if your tumor has a protein called B7-H4.
Birmingham, AlabamaAges 18 years+ - NCT07278986RecruitingEarly Phase 1
Imaging dye during endometrial cancer surgery
This trial tests a dye (CYTALUX) that helps surgeons see endometrial cancer during surgery. You may be eligible if you have endometrial cancer and are scheduled for surgery.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06870903Recruiting
Comparing two lymph node removal methods in vaginal surgery for early endometrial cancer
This trial compares two ways of removing lymph nodes during a vaginal minimally invasive surgery for early-stage endometrial cancer. It aims to find which method is safer and more effective.
Diyarbakır, BaglarAges 18–85 - NCT07270666Recruiting
ctDNA test for guiding endometrial cancer treatment decisions
This trial tests whether a blood test for ctDNA (cancer DNA fragments) can help doctors decide if standard chemotherapy plus an immunotherapy drug is working for people with advanced or recurrent endometrial cancer. It may help tailor your treatment based on how the cancer responds.
Basking Ridge, New JerseyAges 18 years+ - NCT06893861Recruiting
Testing a new blood test for endometrial cancer screening
This study is testing whether a blood test that looks at small molecules (metabolites) can help find endometrial cancer early in post-menopausal women. If you are between 50 and 80 years old and have not had a hysterectomy or certain hormone treatments, you may be able to join.
NaplesAges 50–80 - NCT06896747RecruitingPhase 1/Phase 2
Stem cell therapy for thin uterine lining
This trial tests a new treatment using stem cell particles (exosomes) to help rebuild the lining of the womb in women whose lining is too thin after surgery for scar tissue. It may improve chances of success with IVF.
Xi'an, ShaanxiAges 20–40 - NCT03925311Recruiting
Checking how the uterus is prepared for pregnancy
This study looks at patterns in the uterus and the uterine lining to understand how ready the uterus is for pregnancy. You may be able to join if you are within a specific age range and don’t have certain common uterine conditions.
Hong KongAges 20–40 - NCT04570553Recruiting
Testing a tool during surgery for early endometrial cancer
This study looks at how well a surgical tool is used during standard surgery for early endometrial cancer, and whether it relates to test results from fluid taken in the abdomen. It may help surgeons improve how samples are collected and interpreted during routine care.
York, PennsylvaniaAges 18 years+ - NCT07220239Recruiting
Menstrual cup for early cancer detection in Lynch syndrome
This study tests whether a menstrual cup can collect cells from the uterus to detect early endometrial cancer in women with Lynch syndrome. If you have Lynch syndrome and are due for a routine biopsy, you may be able to use a menstrual cup instead.
Boston, MassachusettsAges 18 years+ - NCT07217353Enrolling by invitation
Testing a new speculum for endometrial biopsies
This trial tests a new type of vaginal speculum designed to make endometrial biopsies (a procedure to take a small sample of the lining of the uterus) more comfortable and effective. If you have had this biopsy before at the Minnesota Oncology Clinic, you may be eligible to help evaluate this new tool.
Englewood, ColoradoAges 18–90 - NCT05857631Recruiting
After-surgery radiation schedule for cervical or uterine cancers
This trial studies a shorter, focused radiation schedule given after surgery for certain higher-risk cervical or endometrial (uterine) cancers. It may help reduce cancer recurrence while checking side effects in the bladder and bowel area.
Navi Mumbai, MaharahstraAges 18–80 - NCT07209449RecruitingPhase 2
Elacestrant with or without abemaciclib for endometrial cancer
This trial tests a new hormone therapy (elacestrant) alone or combined with a targeted pill (abemaciclib) for people with advanced or recurrent endometrial cancer that is hormone-receptor-positive. The goal is to see if these treatments can shrink tumors or slow the cancer's growth.
Basking Ridge, New JerseyAges 18 years+ - NCT07195305Recruiting
Treating adenomyosis bleeding with heat or artery blocking
This study compares two treatments for heavy bleeding caused by adenomyosis: a procedure that uses heat to remove the inner lining of the uterus (endometrial ablation) and a procedure that blocks blood flow to the uterus (uterine artery embolization). If you have been diagnosed with adenomyosis and have tried medication without success, this trial may help decide which treatment is best for you.
BordeauxAges 30–50 - NCT07148154Recruiting
Non-invasive test for endometrial cancer screening
This study tests a simple, non-invasive method to detect endometrial cancer in women after menopause who have abnormal bleeding. It aims to find cancer early in those at higher risk, such as women with certain genetic conditions or risk factors.
L'Hospitalet de Llobregat, BarcelonaAges 40 years+ - NCT06544837Recruiting
Testing a new non-invasive test for women with implantation failure
This trial is testing a new, non-invasive test (called Ora) that checks when your uterine lining is ready for an embryo. It is for women who have had a failed transfer with a genetically normal embryo and are planning a frozen embryo transfer.
HanoiAges 28–45 - NCT07139977RecruitingPhase 2
Study of EV for recurrent endometrial cancer
This trial tests a drug called EV for people with recurrent endometrial cancer that has gotten worse after treatment. It may help if your cancer cells have a specific protein called nectin-4.
Milwaukee, WisconsinAges 18 years+ - NCT07116213Recruiting
Shorter radiation after surgery for high-risk endometrial cancer
This trial studies a new type of radiation therapy (called online adaptive radiotherapy) given in shorter, higher daily doses after surgery for high-risk endometrial cancer. The goal is to see if this approach is safe and effective for reducing side effects while still controlling the cancer.
Beijing, Beijing MunicipalityAges 18–70 - NCT07108270RecruitingPhase 2
Study of dostarlimab plus chemotherapy for advanced or recurrent endometrial cancer
This trial tests a combination of the immunotherapy drug dostarlimab with standard chemotherapy (carboplatin and paclitaxel) for people with advanced or recurrent endometrial cancer that has a specific genetic feature called dMMR or MSI-H. The goal is to see if this combination works better than chemotherapy alone.
Jinan, ShandongAges 18 years+ - NCT07114653Recruiting
Study of POLE mutation in high-risk endometrial cancer
This trial looks at a specific genetic change called POLE mutation in women with endometrial cancer that has a high risk of coming back. It may help doctors understand who could benefit from different treatments.
Banqiao District, New TaipeiAges Any age
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Common questions
- Are there clinical trials for endometrial?
- Yes. Clin2 currently lists 356 recruiting endometrial studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a endometrial trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a endometrial trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.