Clinical trials
Endometrial Cancer Stage I clinical trials
Below are recruiting endometrial cancer stage i clinical trials, each written for real people, not researchers. We’re tracking 141 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07741968Recruiting
Online program to ease fear of cancer returning
This study tests an online program designed to help women with advanced or certain types of breast or gynecologic cancer manage their fear of the disease progressing or returning. The program aims to reduce anxiety and improve quality of life.
Arcadia, CaliforniaAges 18 years+ - NCT06586957RecruitingPhase 1
Study of NKT3964 for advanced solid tumors
This trial tests an experimental drug called NKT3964 for people with certain advanced cancers that have stopped responding to standard treatments. It aims to see if the drug can shrink tumors or slow their growth.
Little Rock, ArkansasAges 19 years+ - NCT06366347RecruitingPhase 2
Maintenance letrozole and abemaciclib for advanced endometrial cancer
This trial tests whether taking two oral medications (letrozole and abemaciclib) after standard chemotherapy can help keep advanced or recurrent endometrial cancer from coming back. It is for people whose cancer is estrogen receptor-positive and has certain favorable genetic features.
Aurora, ColoradoAges 18 years+ - NCT04453904Recruiting
Testing best added chemo and radiation after stage III uterine cancer
This study compares different ways of giving radiation and chemotherapy after surgery for stage III endometrial (uterine) cancer. It aims to find which approach works best to reduce cancer risk and improve outcomes.
Beijing, Beijing MunicipalityAges Any age - NCT04504006Recruiting
Tracking surgery choices for lymph node spread in endometrial cancer
This is an observational study that follows people with endometrial cancer who have had surgery to check and remove pelvic (and sometimes paraaortic) lymph nodes. It looks at how different surgical approaches and any added treatment affect local control (keeping cancer from coming back in the pelvis/nearby areas).
Essen, North Rhine-WestphaliaAges 18 years+ - NCT03787056Recruiting
Blood test marker study in many cancer types
This study measures a blood marker called progastrin (at diagnosis and during treatment) to see how well it predicts response or outcomes. It may help doctors choose or monitor treatment more precisely for several cancer types.
BronAges 18 years+ - NCT04845828Recruiting
Sentinel node biopsy versus full node removal in early uterine cancer
This study compares two ways to check lymph nodes during surgery for early-stage endometrial (uterine) cancer: sentinel node biopsy versus removing more lymph nodes. It may help find whether the less extensive approach can stage the cancer accurately with fewer side effects.
SeoulAges 20–80 - NCT03621904Recruiting
Predicting response to hormone treatment in endometrial cancer
This study looks at whether biopsy test results can help predict how well hormone therapy will work for advanced or recurrent endometrial cancer. It may help doctors choose the most effective hormonal treatment sooner.
NijmegenAges 18–110 - NCT05945407Recruiting
Fertility-sparing treatment for early endometrial cancer
This trial looks at a fertility-preserving treatment plan for people with early-stage endometrial cancer who want to keep the ability to have children. It may help you avoid surgery that removes fertility, if you meet the trial’s safety and eligibility rules.
Beijing, Beijing MunicipalityAges 18–45 - NCT06028724Recruiting
Looking for cancer mutations using a blood test
This study uses a blood test (liquid biopsy) to find genetic changes in advanced solid tumors. It may help doctors choose the right treatment and monitor how well it works over time.
Aviano, PordononeAges 18 years+ - NCT07871838Recruiting
Shorter radiation course for endometrial cancer
This trial tests a shorter course of pelvic radiation for people with endometrial cancer after surgery. It aims to see if it is safe, works well, and improves quality of life.
Montreal, QuebecAges 18 years+ - NCT06417736Recruiting
Study on Endometrial Cancer and Precancer in Young Women
This study tests whether certain treatments can help women aged 18-45 with early-stage endometrial cancer or precancerous changes keep their ability to have children. It uses imaging scans to make sure the cancer hasn't spread.
Hangzhou, ZhejiangAges 18–45 - NCT05876130Recruiting
Radiation after surgery for stage III uterine cancer
This trial studies a specific type of radiation treatment given after surgery for people with stage III endometrial (uterine lining) cancer. It’s meant to see how well this “shorter/targeted” radiation approach works to help control the cancer after hysterectomy and staging.
SeoulAges 20–80 - NCT07838207Recruiting
Molecular markers and outcomes in early-stage endometrial cancer
This study looks at women with certain high-risk types of endometrial cancer that have not spread into the muscle wall of the uterus. It aims to understand how these cancers behave and whether lymph node testing is needed, which could help guide treatment decisions.
Barcelona, BarcelonaAges 18 years+ - NCT07831902RecruitingPhase 3
Hormone tablets plus radiotherapy for certain endometrial cancers
This trial compares two ways to treat endometrial cancer after surgery: a new option of just radiotherapy plus a daily hormone tablet (progestin) versus the current standard of radiotherapy plus chemotherapy. It aims to see if the new option works just as well with fewer side effects.
BathAges 18 years+ - NCT05410717RecruitingPhase 1
CAR-NK cell therapy for certain solid tumors
This early-phase trial tests a lab-made immune cell treatment for advanced solid tumors that show specific targets (including Claudin 6, GPC3, Mesothelin, or AXL). It may help the immune system better recognize and kill tumor cells, but eligibility depends on test results and your overall health.
Guangzhou, GuangdongAges 18–75 - NCT07779109Recruiting
Shorter radiation course for endometrial cancer after surgery
This study tests a shorter, more intense course of radiation therapy after surgery for endometrial cancer. It aims to see if it is safe and works as well as standard radiation, while possibly reducing treatment time.
Zaragoza, ZaragozaAges 18–110 - NCT05974995Recruiting
Robotic or standard surgery for early uterine cancer in obesity
This trial compares robotic-assisted surgery versus standard laparoscopic surgery for people with early-stage uterine (endometrial) cancer and a BMI of 30 or higher. The goal is to see which approach is safer and works better for this group.
RomeAges 18–75 - NCT07622901Recruiting
Fasting and Exercise for Early-Stage Endometrial Cancer
This study tests whether fasting (not eating for extended periods) and exercise before surgery might help improve outcomes for women with early-stage endometrial cancer. Participants will be randomly assigned to either practice fasting and exercise or receive standard care.
Miami, FloridaAges 18 years+ - NCT03438474Recruiting
Lymph node surgery study for certain early endometrial cancers
This trial studies whether adding lymph node removal (lymphadenectomy) during surgery helps people with certain early-stage endometrial cancer. It focuses on patients who do not have visibly enlarged lymph nodes and who can safely have the operation.
AalenAges 18–75 - NCT07612891RecruitingPhase 1/Phase 2
Testing INV-6452 for advanced breast cancer and solid tumors
This study tests a new drug called INV-6452 to see if it is safe and can help control advanced cancers that have grown despite prior treatment. The drug targets specific cancer cell weaknesses, particularly in hormone-sensitive breast cancers without HER2 mutations.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06278857RecruitingPhase 2
Dostarlimab for early-stage MMR deficient endometrial cancer
This trial tests the drug dostarlimab for patients with early-stage endometrial cancer that is MMR deficient. It aims to see if the treatment is safe and effective for those who want to preserve their uterus or cannot have surgery.
Sydney, New South WalesAges 18 years+ - NCT07595224Recruiting
Post-surgery radiation therapy for cervical and uterine cancer
This trial tests a shorter, focused radiation treatment to the pelvis after surgery for cervical or uterine cancer. It aims to reduce the chance of cancer coming back in patients whose doctors recommend additional radiation therapy after their surgery.
Bangkok, BangkokAges 18 years+ - NCT06800612Recruiting
Cancer drug therapy study for gynecologic or breast cancers
This study looks at how well different cancer drugs work for women with breast or gynecologic cancers. Researchers will review medical records to see how patients responded to treatment over time. If you have been treated for breast or gynecologic cancer since 2010, you may be eligible.
BolognaAges 18 years+
Hear when a new Endometrial Cancer Stage I trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for endometrial cancer stage i?
- Yes. Clin2 currently lists 141 recruiting endometrial cancer stage i studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a endometrial cancer stage i trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a endometrial cancer stage i trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.