Clinical trials
Epithelial Ovarian Cancer clinical trials
Below are recruiting epithelial ovarian cancer clinical trials, each written for real people, not researchers. We’re tracking 235 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05086692RecruitingPhase 1/Phase 2
Beta-only IL-2 therapy for advanced solid tumors
This Phase 1/2 study tests a beta-only version of IL-2, an immune-stimulating treatment, to shrink or control advanced or metastatic solid tumors. It’s mainly designed to check safety and to see if it can help patients by improving tumor response.
San Diego, CaliforniaAges 18 years+ - NCT05129969Recruiting
Registry for advanced ovarian or endometrial cancer patients
This registry collects information from people with advanced ovarian or endometrial cancer to better understand care and outcomes. It may help researchers and doctors learn which treatments work best for different patients.
Multiple LocationsAges 18 years+ - NCT04789694RecruitingPhase 3
Prehab program for gynecologic cancer before treatment
This trial tests whether a structured “prehab” program (before major cancer treatment) can improve how well people tolerate therapy and recover. It focuses on people with certain ovarian or early endometrial cancers who need additional treatment planning, including timing of surgery or chemotherapy.
PragueAges 18–85 - NCT04811703RecruitingPhase 1
Testing aerosol chemotherapy through the belly for advanced ovarian cancer
This Phase 1 study tests a new way to deliver chemotherapy inside the abdomen (belly) using a pressurized aerosol during a procedure, along with standard blood (IV) chemotherapy. It may help people with advanced ovarian cancer whose tumors have not progressed but are not removable with surgery yet.
LilleAges 18–75 - NCT04516447RecruitingPhase 1
Testing a new drug for advanced ovarian cancer
This Phase 1 trial studies how well and how safely azenosertib (ZN-c3) works in people with advanced ovarian, fallopian tube, or peritoneal cancer. It may help by offering a new treatment option for cancers that don’t respond well to platinum chemotherapy (platinum-resistant).
Aurora, ColoradoAges 18 years+ - NCT04575935RecruitingPhase 3
Minimally invasive surgery after chemotherapy for advanced ovarian cancer
This trial studies whether doing surgery using smaller incisions after chemotherapy works as well as a more traditional approach for certain people with stage IIIC–IV ovarian, fallopian tube, or primary peritoneal cancer. It may help reduce surgical trauma while aiming for effective tumor removal.
Miami, FloridaAges 18 years+ - NCT04429542RecruitingPhase 1
Test of an EGFR-targeting drug for advanced solid cancers
This Phase 1 study tests the safety of BCA101 (an EGFR-targeting treatment) alone or combined with pembrolizumab. It may help people with certain EGFR-driven advanced cancers, depending on the tumor type, prior treatments, and required biopsy testing.
La Jolla, CaliforniaAges 18 years+ - NCT04055649RecruitingPhase 2
Test of ONC201 and weekly paclitaxel for platinum-resistant ovarian cancer
This Phase 2 study tests whether ONC201 given with weekly paclitaxel can control platinum-resistant ovarian, fallopian tube, or primary peritoneal cancer. It may help by shrinking tumors or slowing growth in people whose cancer has progressed after platinum chemotherapy.
Detroit, MichiganAges 18 years+ - NCT03862677Recruiting
Testing immune markers to predict outcomes in ovarian cancer
This study looks at immune-related markers in people with ovarian cancer to see if they can help predict prognosis (how the cancer may behave). If you qualify, your doctors may use your immune test results alongside other standard treatments like surgery, chemotherapy, and/or immunotherapy.
LeidenAges 18 years+ - NCT03564340RecruitingPhase 1/Phase 2
Testing ubamatamab alone or with cemiplimab for ovarian and MUC16+ cancers
This early-phase study tests ubamatamab, a cancer-targeting antibody, given by itself or with cemiplimab. It is meant to treat adults whose cancer has come back and who may not have other good standard options left.
Birmingham, AlabamaAges 18 years+ - NCT03983226RecruitingPhase 2
Surgery plus niraparib for returning ovarian cancer
This trial tests whether adding niraparib (a pill treatment that targets cancer cell DNA repair) after surgery can help people with ovarian cancer that has come back. It focuses on “platinum-sensitive” cases and tries to remove all visible tumor when possible.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06251947RecruitingPhase 2
Study of Efbemalenograstim alfa for ovarian or cervical cancer chemotherapy
This trial tests a medication (Efbemalenograstim alfa) that helps boost your white blood cell counts during chemotherapy for ovarian or cervical cancer. It aims to reduce the risk of serious infections (febrile neutropenia) while you receive standard treatment with paclitaxel plus carboplatin or cisplatin, with or without bevacizumab.
Changsha, HunanAges 18–70 - NCT03976999Recruiting
Database study for ovarian, fallopian tube, and peritoneal cancers
This is a study that collects information and samples from people diagnosed with epithelial ovarian cancer, fallopian tube cancer, or primary peritoneal cancer. It helps doctors better understand these cancers by building a clinical and biological database, which may improve care planning in the future.
MontpellierAges 18 years+ - NCT06560112RecruitingPhase 2
Combination therapy trial for recurrent ovarian cancer
This trial tests two experimental drugs, AK104 and AK112, for ovarian cancer that has come back after standard platinum chemotherapy. It may be an option if your cancer is a high-grade type and you have had prior treatment.
ShanghaiAges 18 years+ - NCT07039331Recruiting
Short-term fasting for ovarian cancer patients
This trial tests whether short-term fasting before chemotherapy is better than eating freely for women with advanced ovarian cancer. It aims to see if fasting can help treatment work better or reduce side effects.
RomaAges 18 years+ - NCT03878849RecruitingPhase 2
Study drug 2X-121 for ovarian cancer that keeps coming back
This Phase 2 trial tests whether 2X-121 can shrink or control ovarian, fallopian tube, or primary peritoneal cancer that is resistant to platinum chemotherapy. It enrolls people who have had limited prior treatment and can provide a recent or stored tumor sample.
Oklahoma City, OklahomaAges 18 years+ - NCT06172478RecruitingPhase 2
HER3-DXd for advanced solid tumors after prior treatment
This trial tests a new targeted drug called HER3-DXd for people with several types of advanced solid tumors that have stopped responding to standard treatments. The drug is an antibody-drug conjugate, designed to deliver chemotherapy directly to cancer cells that have a protein called HER3 on their surface.
Duarte, CaliforniaAges 18 years+ - NCT06466382Recruiting
Personalized cancer therapy for advanced ovarian cancer
This trial tests whether a treatment plan tailored to your specific tumor and health can work better for advanced ovarian, peritoneal, or fallopian tube cancer. It aims to find the best therapy for each patient to improve outcomes.
Baden, Canton of AargauAges 18 years+ - NCT06879730Recruiting
Studying surgery types for early-stage ovarian cancer
This study looks back at different surgical methods (open or minimally invasive) used for early-stage epithelial ovarian cancer. It aims to compare outcomes and help doctors choose the best approach.
Varese, VareseAges Any age - NCT05827523RecruitingPhase 3
Surgery for ovarian cancer with or without heated chemotherapy
This trial studies whether adding a special heated chemotherapy treatment during surgery (called HIPEC) improves outcomes for some people with ovarian, fallopian tube, or primary peritoneal cancer. It compares surgery alone versus surgery plus HIPEC after you’ve had chemotherapy first.
Sejong, Chungcheongnam-doAges 18–80 - NCT05460000RecruitingPhase 2
Niraparib after early ovarian cancer chemo—short vs long
This trial tests whether taking niraparib (a maintenance anti-cancer pill) for a shorter time after 3 cycles of platinum chemotherapy works as well as taking it after 6 cycles. It is for people with advanced ovarian cancer that has been fully removed (no visible tumor) and is “HRD-positive,” meaning it has certain DNA repair weaknesses.
InnsbruckAges 18 years+ - NCT04520074RecruitingPhase 3
Chemo after surgery for BRCA1/2 wild-type ovarian cancer
This Phase 3 trial studies a three-step “extra” chemotherapy plan after surgery for people with certain advanced ovarian, fallopian-tube, or primary peritoneal cancers. The goal is to improve outcomes by lowering the chance the cancer comes back.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07724106RecruitingPhase 1
NeoOVSV vaccine for ovarian cancer after surgery
This trial tests a personalized vaccine made from your own tumor tissue called NeoOVSV. It is meant to train your immune system to fight any remaining cancer after surgery. The vaccine is a personal treatment because it uses your tumor's unique markers.
Chengdu, SichuanAges 18–75 - NCT07676890RecruitingPhase 1
Study of a personalized vaccine for ovarian cancer after surgery
This trial tests a personalized vaccine made from your tumor's genetic material. It is given after surgery to help your immune system recognize and attack any remaining cancer cells, with the goal of preventing the cancer from coming back.
Chengdu, SichuanAges 18–75
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Common questions
- Are there clinical trials for epithelial ovarian cancer?
- Yes. Clin2 currently lists 235 recruiting epithelial ovarian cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a epithelial ovarian cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a epithelial ovarian cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.