Clinical trials
Family clinical trials
Below are recruiting family clinical trials, each written for real people, not researchers. We’re tracking 592 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05489549Recruiting
Study of heart amyloid risk in people with TTR gene variants
This study looks at people who carry certain TTR gene variants, which can cause a specific type of heart amyloid buildup. It also includes people with symptoms, to understand how the condition develops and how it may be monitored.
New York, New YorkAges 30–80 - NCT05346016Enrolling by invitation
Study of family gut bacteria passed between relatives
This study looks at whether gut bacteria are shared and stay stable within families over generations. If you’re part of the PEARL study family in England, you may be invited to share samples so researchers can understand how these bacteria move through households.
Norwich, NorfolkAges Any age - NCT05348564Recruiting
Family genetic screening methods for heart rhythm risk
This study compares two ways to find relatives who may carry a specific inherited genetic change. It may help your family learn faster who should get follow-up testing and care.
Lancaster, PennsylvaniaAges 18 years+ - NCT05267665Recruiting
Family-involved PTSD therapy coaching for Veterans
This study tests a brief way to include a Veteran’s family member to improve PTSD treatment results and help people stay engaged in care. It’s for Veterans who are just starting evidence-based PTSD therapy and have a closely involved family member who can participate too.
Boston, MassachusettsAges 18 years+ - NCT05284513Enrolling by invitation
Care team study for families with high cholesterol
This study tests a “reach everyone” approach in primary care clinics to improve care for people with familial hypercholesterolemia (families with very high cholesterol). It may help families get recognized sooner and get the right follow-up.
Multiple Locations, PennsylvaniaAges 26 years+ - NCT05126290Recruiting
Study for CTNNA1 gene family members
This study looks at people who carry a specific “loss-of-function” CTNNA1 gene change—or who are closely related to someone who does. It’s designed to better understand this genetic risk in families and may help guide future care and monitoring.
Philadelphia, PennsylvaniaAges 18 years+ - NCT04941599RecruitingPhase 2
2-HOBA to improve “good cholesterol” function in FH
This Phase 2 trial tests whether 2-HOBA can improve how “good cholesterol” (HDL) works in people with familial hypercholesterolemia (FH). If HDL works better, it may help lower heart risk markers. You would need to meet several heart, health, and medication-related safety checks.
Nashville, TennesseeAges 18–69 - NCT04929457Enrolling by invitation
Screening to detect inherited high cholesterol
This study tests a digital screening method to help identify and diagnose familial hypercholesterolemia, an inherited condition that can cause very high cholesterol. If you participate, you may be invited to complete screening steps to see whether they can find the condition early.
StockholmAges Any age - NCT04677998Recruiting
Personalized monitoring and treatment plan for stomach polyps
This trial tests a personalized plan for regularly checking and treating stomach and first-part of intestine polyps in people with familial adenomatous polyposis (FAP). It may help by catching problems early and choosing the right intervention at the right time.
Houston, TexasAges 18 years+ - NCT04678011Recruiting
Personalized follow-up to prevent cancer after FAP surgery
This trial studies a tailored plan for surveillance (check-ups) and interventions to find and remove new growths early in people with familial adenomatous polyposis (FAP) after bowel surgery. It may help lower the chance of cancer by closely monitoring and treating polyps when they appear.
Houston, TexasAges 18 years+ - NCT04529967Recruiting
Screening kids for inherited high cholesterol
This study checks children ages 1 to 3 during routine care to see who may have familial hypercholesterolemia, a genetic condition that causes high cholesterol. Early identification can help families learn about next steps and prevention.
Hefei, AnhuiAges 1–3 - NCT04272697Recruiting
Registry study for familial cholesterol conditions
This trial is a global registry that collects health and genetic information from people with familial hypercholesterolemia (FH) and sometimes from their relatives. The goal is to better understand FH and how it presents, which can help improve care for families affected by high cholesterol.
LondonAges Any age - NCT00582621Recruiting
Family history study to support genetic testing research
This study collects family and medical history to better understand inherited causes of blood cancers (like lymphoma) and related conditions. It may help researchers build genetic findings that could improve how families understand their risk and future care.
Basking Ridge, New JerseyAges Any age - NCT03657732Recruiting
Study of inherited Alzheimer’s genes in families
This study looks at people from families with inherited Alzheimer’s disease, including those who may be cognitively normal. It uses medical checkups and brain/nerve tests to better understand Alzheimer’s risk and symptoms in families with specific gene changes.
Hefei, AnhuiAges 18 years+ - NCT03443999Recruiting
Registry to follow patients with a sirolimus stent
This study is a follow-up registry that tracks how people do after doctors place a specific type of drug-eluting coronary stent. It may help doctors understand safety and outcomes of the Supraflex stent in real-world care.
Breda, North BrabantAges 18 years+ - NCT02693548Recruiting
Study of families with familial high cholesterol
This is a study that follows people with a genetic form of very high cholesterol (familial hypercholesterolemia) and their close relatives. It aims to better understand this condition in real families and how it affects health over time.
Madrid, MadridAges 15 years+ - NCT02669797Enrolling by invitation
Family-based program to help families eat dinner together
This study offers an intervention focused on family dinners to help children improve their eating habits. It targets children who eat family dinners rarely and have a higher weight range, to see if the program can help improve health over time.
Aurora, ColoradoAges 5–10 - NCT00461188Recruiting
Study of inherited pituitary tumor causes
This study looks at the genetics behind pituitary tumors, especially pituitary growth-hormone–related tumors like acromegaly. It may help doctors better understand who these tumors affect and why, which can guide future diagnosis or care.
LeicesterAges 6 years+ - NCT01109368Recruiting
Registry for people with inherited very high cholesterol
This trial is a registry that collects information from people with homozygous familial hypercholesterolemia (an inherited condition causing extremely high “bad” cholesterol). It may help researchers better understand the condition and support future studies.
New York, New YorkAges Any age - NCT07166055Recruiting
Family dance therapy for children with motor disabilities
This study tests whether dancing with your family can help children with motor challenges move better and have fun. It aims to see if this kind of therapy is practical and enjoyable for children ages 3 to 14.
ValenciaAges 3–14 - NCT00024804Recruiting
Understanding Bone and Mineral Health Disorders
This study tracks people with bone diseases or problems with how their body handles calcium, phosphorus, and other minerals. Researchers want to understand how these conditions develop and change over time to help improve future treatments.
Bethesda, MarylandAges 1 day–100 years - NCT05490238Recruiting
Wrist vs arm access for complex heart procedures
This study compares using the wrist (radial artery) versus a different access site (conventional radial access approach) during complex, larger “bore” heart procedures to open blocked coronary arteries. It aims to see which approach is safer and works better for challenging cases like chronic blockages or heavily calcified arteries.
ArlonAges 18 years+ - NCT02760108Recruiting
Parkinson’s Families Project for people with family links
This project is for people age 16 and older who have Parkinson’s (or similar symptoms called parkinsonism). It focuses on people with a family history and/or symptoms that started before age 45, to better understand Parkinson’s in families.
LondonAges 16 years+ - NCT04006535Recruiting
Genetic testing study for vasculitis in families and children
This study uses a detailed DNA test to look for possible genetic causes of vasculitis (inflammation of blood vessels) in children and adults. It may help researchers better understand why vasculitis happens, especially in families.
Paris, Île-de-France RegionAges Any age
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Common questions
- Are there clinical trials for family?
- Yes. Clin2 currently lists 592 recruiting family studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a family trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a family trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.