Study of inherited Alzheimer’s genes in families
Part of Brain & nervous system, Mental health clinical trials.
This study looks at people from families with inherited Alzheimer’s disease, including those who may be cognitively normal. It uses medical checkups and brain/nerve tests to better understand Alzheimer’s risk and symptoms in families with specific gene changes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Have a family history of Alzheimer’s: at least two close relatives with it, across at least three affected family generations
- Have (or be part of) a family with a known Alzheimer’s gene change: APP, PSEN1, or PSEN2
- Be age 18 or older
- Be able to complete study visits and assessments (not bedridden)
- For people in the study with Alzheimer’s or memory problems: have diagnoses that fit Alzheimer’s or mild cognitive impairment—other causes must be ruled out
- You must be able to provide (or have) two reliable people who know your health and day-to-day functioning
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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