Clinical trials
Foot clinical trials
Below are recruiting foot clinical trials, each written for real people, not researchers. We’re tracking 292 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06352788Recruiting
Testing custom braces for foot and ankle injuries
This trial studies how well custom leg braces help people with long-term foot or ankle problems from a past injury. It looks at whether wearing a special brace can reduce pain and improve walking.
San Diego, CaliforniaAges 18–65 - NCT06370325Recruiting
Electrical stimulation after ankle fracture surgery
This study tests whether a gentle electrical stimulation device placed on the skin around the ankle can help recovery after ankle fracture surgery. It may reduce pain, swelling, and healing time.
New York, New YorkAges 18–70 - NCT06433648Recruiting
Powered knee study for above-knee amputee walkers
This study looks at how a powered (motorized) prosthetic knee joint affects walking in people with one above-knee amputation. It aims to find out if the powered knee makes walking easier or more natural.
Chicago, IllinoisAges 18–95 - NCT06483620Recruiting
Arabic quality of life questionnaire for diabetic neuropathy
This trial tests a new Arabic questionnaire to measure quality of life for people with diabetic neuropathy. It helps doctors understand how nerve pain affects daily life.
Cairo, Giza GovernorateAges 18–70 - NCT06515093Recruiting
New skin grafts for diabetic foot and venous leg ulcers
This study tests two new skin graft products (PelloGraft for diabetic foot ulcers and SanoGraft for venous leg ulcers) to see if they heal wounds faster than standard care. If you have a hard-to-heal foot or leg ulcer, this trial may offer a new option.
Vista, CaliforniaAges 18 years+ - NCT06541119Recruiting
Strengthening a leg muscle for bunion pain and function
This study tests whether strengthening a specific muscle on the outside of your lower leg can help reduce pain, improve foot alignment, and make it easier to walk and do daily activities if you have a bunion (hallux valgus).
GizaAges 18–60 - NCT06547684Recruiting
Shock wave therapy for foot stiffness after stroke
This trial tests whether shock wave therapy can help relax the tight calf muscles that cause foot drop after a stroke. It may help you walk better and reduce foot stiffness.
Vila-real, CastellonAges 18 years+ - NCT06567093Recruiting
Massage for pain during heel blood draw in newborns
This study tests whether a gentle leg and heel massage can help reduce pain in newborns during a standard heel blood test. It's for healthy babies born at full term (38–41 weeks) who are less than a month old.
Bartın, ProvinceAges 1 day–4 weeks - NCT06581978Recruiting
Early warning for foot health in children
This study looks at the health of children's feet and aims to spot early signs of foot problems. It may help guide how to prevent issues like flat feet.
Guangzhou, GuangdongAges 6–18 - NCT06639178Recruiting
Cream to prevent hand-foot syndrome from capecitabine in breast cancer
This trial tests whether a special cream containing N-acetylcysteine and urea can prevent the painful hand-foot syndrome often caused by the chemotherapy drug capecitabine. If you have breast cancer and are about to start capecitabine, this study may help reduce side effects.
Aviano, PordenoneAges 18 years+ - NCT06665607Recruiting
Foot muscle training for people with MS
This study tests whether training the small muscles in your feet can improve your walking and balance if you have multiple sclerosis (MS). It is for people with moderate disability, so you can still walk but may have some trouble.
ValladolidAges 18–70 - NCT06693180Recruiting
Hyperbaric oxygen therapy for diabetic foot ulcers
This trial is testing whether hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) can help heal diabetic foot ulcers. It is for people with diabetes who have a foot ulcer that is not healing well.
Amsterdam, North HollandAges 18 years+ - NCT06699433Recruiting
AI virtual pediatric patient training for primary care doctors
This trial uses artificial intelligence to create virtual standardized pediatric patients. It helps train doctors who work in primary care settings, like community health centers and clinics.
Guiyang, GuizhouAges Any age - NCT07688876Recruiting
Comparing two treatments for long-term heel pain
This trial tests two minimally invasive procedures—pulsed radiofrequency and a dextrose injection—to see which better relieves chronic heel pain from plantar fasciitis that hasn't improved with other treatments.
AnkaraAges 18–70 - NCT06734832RecruitingPhase 3
Vaccine trial for hand, foot, and mouth disease
This trial tests a new two-in-one vaccine to protect children against hand, foot, and mouth disease caused by two common viruses (EV71 and CA16). It is for healthy kids ages 6 months to 5 years and will check if the vaccine is safe and works well.
Hefei, AnhuiAges 6 months–5.9 years - NCT06767631Recruiting
Muscle and nerve changes after botox for stroke foot tightness
This study looks at how botulinum toxin (botox) injections affect the muscles, tendons, and nerves in the lower leg of people who have had a stroke and have a tight, twisted foot (equinovarus). It aims to understand these changes to improve future treatments.
LeuvenAges 40–60 - NCT06828653Recruiting
Comparing 3D-printed vs standard ankle braces for walking
This study compares custom-made ankle-foot braces made with a digital 3D printing method versus the traditional plaster cast method. It aims to find out which type is more comfortable and effective for people with conditions like cerebral palsy, stroke, or spinal cord injury who need a brace to help them walk better.
Mississauga, OntarioAges 8 years+ - NCT06874517Recruiting
Foot shape and big toe angle study
This study looks at whether the length of your second toe relates to a condition called hallux valgus (a bunion, where the big toe angles toward the other toes). Researchers will measure foot X-rays to compare two common foot shapes: Greek foot (longer second toe) and Egyptian foot (shorter second toe).
Istanbul, BeylikdüzüAges 60–80 - NCT06889792Recruiting
Preventing disease with healthy lifestyle screening in the ER
This trial tests if screening and education in the emergency department can help people adopt healthier habits to prevent long-term diseases. You may join if you have at least one unhealthy behavior like smoking, drinking too much alcohol, poor diet, or not exercising.
Hong KongAges 18 years+ - NCT06899113Recruiting
Comparing a new imaging device to standard blood flow tests
This trial tests a new camera that uses light to check blood flow in your legs. It compares the camera's results to standard tests like ABI and Doppler ultrasound to see if it works as well.
Lake Success, New YorkAges 18 years+ - NCT06904989Recruiting
Helping foot nerve pain from chemo with shoe inserts
This trial tests whether special shoe inserts can reduce foot pain and numbness caused by chemotherapy for breast cancer. It may help you feel better and walk more easily.
GothenburgAges 18 years+ - NCT06912646Recruiting
Laser therapy for foot pain from idiopathic neuropathy
This trial tests a laser device for temporary relief of foot pain from peripheral neuropathy when the cause is unknown. It may help if you have constant foot pain and are not diabetic.
Miramar, FloridaAges 22 years+ - NCT06936163Recruiting
Surgery for foot deformities in hereditary spastic paraplegia
This study looks at how well surgery works for foot problems like tight heel cords or clubfoot in people with hereditary spastic paraplegia (HSP), a condition that causes leg stiffness. It aims to see if surgery can improve walking, reduce pain, and prevent falls.
Shanghai, Shanghai MunicipalityAges 10–45 - NCT06939673Recruiting
Miro3D wound matrix for healing wounds and ulcers
This trial tests a special wound dressing called Miro3D that helps heal open wounds and ulcers. It may be a good option if you have a wound that is not healing, especially if it has tunnels or pockets under the skin.
Coconut Creek, FloridaAges 18 years+
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Common questions
- Are there clinical trials for foot?
- Yes. Clin2 currently lists 292 recruiting foot studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a foot trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a foot trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.