Clinical trials
Foot clinical trials
Below are recruiting foot clinical trials, each written for real people, not researchers. We’re tracking 292 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04916457Recruiting
Studying skin germs in diabetes-related foot skin problems
This study collects skin samples from people with and without type 2 diabetes, especially around foot skin problems, to learn how skin “micro-germs” differ. The goal is to better understand what’s going on in diabetic skin lesions and possibly guide future care.
Guangzhou, GuangdongAges 18–80 - NCT04920253Recruiting
Testing a water-jet treatment to heal certain foot and leg wounds
This trial tests a new “micro water jet” device (Debritom+) to help heal specific hard-to-heal wounds in people who can attend frequent visits. If you qualify, you’ll be assigned to the device treatment or standard care and monitored to see how well the wound heals.
Bradenton, FloridaAges 18 years+ - NCT05075005Recruiting
Study tests foot muscle effects of different walking surfaces
This study compares how different walking surfaces affect foot muscle activity in people with plantar fasciitis and in healthy adults. It’s aimed at better understanding what changes happen in the foot and how terrain might influence symptoms and muscle function.
Gainesville, FloridaAges 18–100 - NCT05131399Recruiting
Test an off-the-shelf carbon ankle brace for drop foot walking
This trial studies whether a ready-made carbon ankle-foot brace (AFO) improves walking when someone has “drop foot” (trouble lifting the front of the foot). It’s meant to help with standing and stability by supporting the ankle and foot.
AngersAges 18 years+ - NCT05154253RecruitingPhase 1
Improving ankle push-off in children with cerebral palsy
This early (Phase 1) study tests a way to improve how well the ankle muscles help you push off when walking in cerebral palsy. If the ankle function improves, it may lead to a more comfortable and safer walking pattern.
Minneapolis, MinnesotaAges 8–21 - NCT05228340Recruiting
Treating toe ulcers by releasing tight tendons to prevent recurrence
This study looks at whether a minor procedure on a toe (called a flexor tenotomy) can reduce the chance that diabetic toe ulcers come back. It is for adults with diabetes who have nerve damage in the feet and have had toe ulcers before.
Amsterdam, North HollandAges 18 years+ - NCT05643079Recruiting
Bone screw and tendon transfer for heel bone realignment
This trial studies a specific surgical technique for people who need heel bone realignment along with a tendon transfer. It tests whether using a human donor bone screw helps the bone heal and the tendon work after surgery.
ViennaAges 18 years+ - NCT05644522Recruiting
At-home brace study for leg support and walking
This study tests an at-home wearable activity monitor and brace-related walking support for people who already use a knee-ankle-foot brace. It may help researchers understand how brace use and day-to-day movement relate to walking ability.
Chicago, IllinoisAges 18–89 - NCT05818410Recruiting
Brain and tech training after below-knee leg loss
This study looks at how your brain works with assistive technology after losing a leg below the knee. It may help researchers improve how prosthetic devices feel and function by measuring brain and movement signals during training.
BrusselsAges 18–65 - NCT05912153Recruiting
SPECT-CT vs MRI to diagnose foot and ankle arthritis
This study compares two imaging tests—SPECT-CT and MRI—to see which one best helps diagnose osteoarthritis (wear-and-tear joint arthritis) in the ankle and midfoot/hindfoot. It may help confirm the right diagnosis so treatment can be better targeted.
GroningenAges 18 years+ - NCT06066801Recruiting
Bedside bone biopsy for diabetic foot infection
This trial is testing a new way to take a small sample of infected bone from the foot of people with diabetes. It aims to see if a bedside biopsy is safe and accurate for diagnosing bone infection, so you may avoid more invasive procedures.
ParisAges 18 years+ - NCT06078371Recruiting
Opioid-free pain treatment after broken bone surgery
This study compares standard pain treatment using opioids to a new opioid-free pain block for people who had surgery for broken bones. The goal is to find safer, non-addictive ways to manage pain after trauma.
Kansas City, KansasAges 18 years+ - NCT06084052Recruiting
Mobile app study to prevent foot ulcers in diabetes
This trial tests a mobile app to help prevent foot ulcers in people with diabetes who are at high risk. You will use the app to track your foot health and get advice to keep your feet safe.
LondonAges 18–100 - NCT06127264Recruiting
Testing force in a carbon fiber leg brace cuff
This study tests how well a sensor measures force in the top part of a carbon fiber leg brace. It may help improve brace design for people who need them.
Iowa City, IowaAges 18–90 - NCT06141811Recruiting
Long-term safety study for diabetic foot ulcer treatment
This study follows up on patients who received an experimental cell sheet (ALLO-ASC-DFU) or a placebo in a previous trial. It checks for any new safety concerns over time.
Bucheon-si, Gyeonggi-doAges 19–75 - NCT06146088RecruitingPhase 4
EV71 Vaccine Consistency Study for Children
This study tests three batches of an EV71 vaccine (which prevents hand, foot, and mouth disease) to see if they work the same. Your child would receive two doses, several weeks apart, and have blood tests to check their immune response.
Baoji, Shaan XIAges 6 months–2.9 years - NCT06211504RecruitingPhase 4
Foot implant plus standard surgery for flatfoot
This study tests whether placing a small implant in the sinus tarsi (a space in the side of the foot) during a standard flatfoot surgery helps improve the results. It's for adults with stage II adult acquired flatfoot deformity who have not improved with conservative care.
Hässleholm, Skåne CountyAges 16–75 - NCT06234124Recruiting
A shoe to improve walking after stroke
This study tests a special shoe that changes friction to help improve walking for people who have had a stroke. It lasts 6 months and involves daily exercises at home.
Chicago, IllinoisAges 18 years+ - NCT06236750Recruiting
Testing a human tissue wound covering for hard-to-heal ulcers
This study is testing a special wound covering made from donated human tissue (amnion/chorion membrane) to see if it helps heal stubborn diabetic foot ulcers or venous leg ulcers that haven't improved with standard care. The covering is placed on the wound to help it heal.
Kobe, HyōgoAges Any age - NCT06251297Recruiting
Reflexology to prevent nerve damage from chemotherapy
This study tests if foot reflexology can help prevent nerve damage caused by a chemotherapy drug called oxaliplatin in people with colorectal cancer. If it works, it could reduce pain, tingling, or numbness in the hands and feet.
Toulouse, CHU de ToulouseAges 18 years+ - NCT06263439Recruiting
Watching hand, foot, and mouth disease in children
This study simply watches children with hand, foot, and mouth disease or herpangina to learn more about these illnesses. Your child's regular care won't change, and no extra treatments are given.
Clermont-FerrandAges Up to 10 years - NCT06277362Recruiting
New Leg-Saving Treatment for Critical Limb Ischemia
This study tests a new way to restore blood flow to the leg in people who have wounds or dead tissue on their foot and have run out of other treatment options. It's for those who have already tried angioplasty twice without success or have severely hardened small arteries.
Ancona, AnconaAges 18 years+ - NCT06308380Recruiting
Rehab for tight leg muscles and ankle pain
This trial tests a rehabilitation program for people with tight back leg muscles that cause ankle pain, trouble walking, or daily activity limits. It may help if you have chronic ankle pain or a condition like clubfoot.
Granollers, BarcelonaAges 20–90 - NCT07696728Recruiting
Pulsed magnetic field therapy for diabetic foot ulcer sensation
This trial tests whether a painless pulsed electromagnetic field treatment can improve feeling in diabetic foot ulcers. It is designed for people with type 2 diabetes who have had a foot ulcer for a while and have lost some sensation due to nerve damage.
Faisalabad, Punjab ProvinceAges 40–60
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Common questions
- Are there clinical trials for foot?
- Yes. Clin2 currently lists 292 recruiting foot studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a foot trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a foot trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.