Clinical trials
Functionality clinical trials
Below are recruiting functionality clinical trials, each written for real people, not researchers. We’re tracking 2,577 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06078189Recruiting
Thumb joint surgery for arthritis: comparing two procedures
This trial tests two surgical treatments for thumb base arthritis (rhizarthrosis) when other treatments like splints and injections haven't worked. It compares a newer joint implant (arthroplasty) with a standard procedure to remove a small bone (trapezectomy). The goal is to see which helps patients recover hand function better.
ParisAges 45–85 - NCT06090357Recruiting
How footplant changes after foot and ankle surgery
This study uses special pressure mats to measure how your foot pushes against the ground before and after surgery. It helps doctors learn how surgeries change your walking and balance.
BolognaAges 18–75 - NCT05919459Recruiting
Therapy program to help parents and teens with scoliosis anxiety
This study tests whether Acceptance and Commitment Therapy (a structured talk-therapy approach) can improve parents’ and teens’ psychological well-being. It compares this therapy to other active support programs for families dealing with adolescent idiopathic scoliosis.
Hong KongAges 10–60 - NCT06078852Recruiting
FSHD Diaphragm Ultrasound Study
This study uses ultrasound to look at the diaphragm in people with FSHD. It aims to better understand how FSHD affects breathing muscles over time.
RomaAges 18 years+ - NCT05974553Recruiting
Dialectical behavior therapy for justice-involved veterans
This study tests whether dialectical behavior therapy (DBT, a structured therapy skills program) can help veterans with stress or behavior challenges related to justice system involvement. It may help by teaching practical coping skills in a group setting.
Aurora, ColoradoAges 18 years+ - NCT06025500Recruiting
Muscle function before and after lung valve treatment
This study looks at how well your leg muscles work before and after getting special valves placed in your lungs. It uses an exercise bike test and an MRI scan to measure muscle changes, and the results may help people with COPD breathe better.
GroningenAges Any age - NCT05928247Recruiting
Behavior program for frequent challenging behaviors in children
This trial tests a structured (manualized) assessment and treatment approach for children who have very frequent challenging behaviors despite prior help. It aims to reduce these behaviors and improve daily functioning by targeting what keeps the behavior going.
Somerset, New JerseyAges 3–17 - NCT05978414Recruiting
Jaw and Pelvis Connections in Women After Prolapse Surgery
This study looks at how the jaw joint and pelvis may be connected in women who have had surgery for pelvic organ prolapse and also have endometriosis. It aims to find new links that could help guide treatment.
PoznanAges 18–60 - NCT05975697Recruiting
Electrical stimulation after thrombectomy for arm paralysis
This study tests whether a special electrical stimulation therapy can improve arm movement, physical activity, and quality of life after a thrombectomy. You may be considered if you are an adult with arm paralysis and can communicate after your procedure.
Adana, YüreğirAges 18 years+ - NCT05843604Recruiting
Brain and thinking tests to study OCD treatment resistance
This study looks at brain and thinking (cognitive) markers to understand why some people with obsessive-compulsive disorder (OCD) don’t respond as well to treatment. If you have OCD, you may be asked to take tests and follow the study rules to help researchers better predict treatment resistance.
PoitiersAges 18–70 - NCT05790668Recruiting
Motivation tips to reduce frequent rewards for destructive behavior
This trial tests behavior-support strategies that may help gradually reduce how often a child’s destructive behavior gets reinforced. It’s aimed at children with frequent destructive behavior that continues even with past treatment.
New Brunswick, New JerseyAges 3–17 - NCT05708105Recruiting
Testing ultrasound and near-infrared light to predict brain bleeding
This study looks at using two noninvasive tools on very preterm newborns to better predict whether an intraventricular hemorrhage (bleeding in the brain’s fluid spaces) may happen. If successful, it could help doctors spot risk earlier and monitor or treat babies sooner.
Calgary, AlbertaAges Any age - NCT05814094Recruiting
Testing a red blood transfusion approach during ECMO
This study looks at whether giving red blood cell transfusions in a specific way is practical and safe for people receiving ECMO (a heart-lung support machine). It’s mainly a feasibility study, meaning the goal is to see if the plan can be carried out smoothly and safely.
Camperdown, New South WalesAges 18 years+ - NCT05826587Recruiting
Mobile coaching to prevent falls during heart rehab
This study adds a personalized home exercise program delivered by a smartphone app to standard outpatient heart rehabilitation. It aims to improve balance and strength to lower the chance of falling during the rehab period.
Scottsdale, ArizonaAges 18 years+ - NCT05587751Recruiting
Testing how gender-affirming care affects lung function
This study checks whether gender-affirming treatments change breathing/lung test results over time. It may help doctors understand any lung-related effects for transgender and gender-diverse people.
Rochester, MinnesotaAges 14 years+ - NCT05588284Enrolling by invitation
Check whether a special treatment protects vein valves after clot
This study enrolls people with an acute blood clot in the thigh or pelvis veins to see how well a procedure called PCDT (using a Zelante device) preserves the function of vein valves. It may help reduce complications like ongoing vein problems after a clot.
Chuzhou, AnhuiAges 18–80 - NCT05436600Recruiting
Exercise program for people with narrowed neck arteries
This trial studies whether a supervised exercise program can improve mobility and balance in people who have narrowed carotid arteries in the neck but no stroke symptoms. If you fit the criteria, the goal is to see whether exercise helps your movement and safety without increasing risks.
Baltimore, MarylandAges 18–89 - NCT05482022Recruiting
Test speaking valve effects for people with tracheostomy and brain injury
This study checks whether a speaking valve changes breathing, swallowing, and voice in people who have a tracheostomy after a brain injury. It may help doctors find safer ways to improve communication and function for people who are in a minimal conscious or unresponsive state.
RaananaAges 18 years+ - NCT05447819Recruiting
Shoulder replacement for worn rotator cuff joint
This trial studies a specific type of reverse shoulder implant to improve shoulder function after severe joint wear. It’s for people whose shoulder pain and loss of function did not improve enough with non-surgical treatments and who need shoulder arthroplasty.
Hellerup, DenmarkAges 50 years+ - NCT05621278Recruiting
School study of mental and physical well-being from kids to adults
This study follows students from middle school through high school and asks their parents and teachers questions about mental well-being and physical (body-related) health. It may help researchers understand what supports healthy development over time.
Beijing, Beijing MunicipalityAges 9–65 - NCT05556655Recruiting
Brain stimulation and how it changes memory task performance
This study tests how a brain stimulation method affects how well you do thinking and memory tasks. You would complete cognitive testing before and after the stimulation, and the researchers look at whether your performance changes.
Fort Collins, ColoradoAges 18–65 - NCT05611775Recruiting
Spinal surgery patients tracked for daily activity after surgery
This trial follows adults who are getting a multi-level spinal deformity correction surgery with special pelvic attachment. It looks at how well you return to real-life function and activity after surgery using follow-up visits at Mayo Clinic.
Rochester, MinnesotaAges 18 years+ - NCT05010343RecruitingPhase 2
Carbon ion radiation guided by scans for prostate cancer
This Phase 2 trial tests whether using detailed scans (PSMA PET/CT and MRI) to guide carbon ion radiation—delivered in a focused way—can treat localized prostate cancer. It may help target the treatment more precisely while avoiding areas that are not involved.
ShanghaiAges 45–85 - NCT05099341Recruiting
Study blood HDL differences in depression
This study compares a special type of cholesterol in the blood (HDL) between people with depression and people without depression. Researchers want to understand how depression may be linked to differences in HDL and related blood markers.
DijonAges 18 years+
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Common questions
- Are there clinical trials for functionality?
- Yes. Clin2 currently lists 2,577 recruiting functionality studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a functionality trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a functionality trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.