Clinical trials
Gastric (Stomach) Cancer clinical trials
Below are recruiting gastric (stomach) cancer clinical trials, each written for real people, not researchers. We’re tracking 176 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04809025Recruiting
Testing biopsy samples vs surgery samples for stomach cancer testing
This study compares two ways of getting stomach cancer tissue: a camera-guided biopsy and a tissue sample taken during planned stomach surgery. The goal is to see which sample better supports molecular (gene-based) testing to guide diagnosis.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06085755RecruitingPhase 1/Phase 2
Combination drug therapy for HER2-low stomach cancer
This trial tests two targeted drugs, trastuzumab deruxtecan and afatinib, together for advanced stomach or gastroesophageal junction cancer that has low levels of the HER2 protein. The goal is to see if the combination shrinks tumors or slows cancer growth.
SeoulAges 19 years+ - NCT05184803RecruitingPhase 2
Pre-surgery chemo for advanced stomach cancer with lymph spread
This Phase 2 study tests a combination chemotherapy regimen given before surgery for stomach cancer that cannot be fully removed (unresectable), including spread to lymph nodes. The goal is to shrink the cancer and improve control with a well-known set of medicines given in a specific order.
Seoul, SeoulAges 19 years+ - NCT07509008RecruitingPhase 1/Phase 2
Immune cells in the belly for stomach cancer spread
This trial tests a new type of immune cell (called a CAR NK cell) given directly into the belly, along with standard surgery and chemotherapy, for stomach cancer that has spread to the belly lining. The goal is to see if this treatment is safe and can help control the cancer.
Houston, TexasAges 18 years+ - NCT07441850Recruiting
Digital rehab for stomach cancer patients after chemo or radiation
This trial is testing a smartphone-based exercise and recovery program for people with stomach cancer who have had chemo or radiation before surgery. It aims to help you get back on your feet faster after surgery.
BeijingAges 18–70 - NCT07464470Recruiting
Comparing stomach cancer and brain metastasis genetics
This trial studies stomach and esophageal cancers that spread to the brain. It compares the genetic makeup of the original tumor to the brain metastasis, which may help find better treatments.
MoscowAges 18 years+ - NCT04958720Recruiting
Registry for esophagus and stomach cancer patients
This study keeps an organized record of people diagnosed with esophagus, gastroesophageal junction, or stomach cancer. It helps researchers learn from real-world outcomes, based on health information collected over time.
Alicante, AlicanteAges 18–100 - NCT05652348Recruiting
Predicting outcomes after heated chemotherapy for stomach or colon spread
This study tries to better predict how well patients do after heated chemotherapy placed in the abdomen during surgery for stomach or colon cancer that has spread to the lining of the abdomen. It may help doctors choose the best treatment plan and timing for future patients.
BerlinAges 18 years+ - NCT07800754Recruiting
Stomach and esophageal cancer care in Greece
This study is for people with stomach or esophageal cancer in Greece. It is not a treatment study; it simply looks at how patients are diagnosed and treated in regular practice, so participating won't change your care.
AlexandroupoliAges 18–130 - NCT05274048RecruitingPhase 1
Neratinib plus antibody-drug for HER2-positive stomach or esophagus cancer
This early-phase trial tests neratinib together with an antibody-drug to treat advanced HER2-positive gastro-esophageal (stomach/esophagus) cancer that can’t be removed by surgery. It’s for people whose cancer has progressed after at least one HER2-targeted treatment, aiming to shrink tumors and improve outcomes.
Palo Alto, CaliforniaAges 18 years+ - NCT07714980Recruiting
Acupoint stimulation timing for stomach cancer surgery recovery
This trial tests whether giving a gentle, needle-free acupoint stimulation before or after stomach cancer surgery helps speed up recovery. The stimulation uses a small device on the skin, similar to a tens unit, to support recovery after laparoscopic gastrectomy.
Dongying, ShandongAges 18–80 - NCT06925243RecruitingPhase 3
Apatinib, Sintilimab, and Chemo for Intestinal Gastric Cancer
This phase 3 trial tests adding the targeted drug apatinib to a standard combination of sintilimab (immunotherapy) and chemotherapy (SOX regimen) given before surgery for a specific type of stomach or gastroesophageal junction cancer (intestinal type, HER2-negative). The goal is to see if the three-drug combination works better than the two-drug combination in shrinking the tumor and improving outcomes before surgery.
Lanzhou, GansuAges 18–75 - NCT06949033RecruitingPhase 3
Cadonilimab with chemo for stomach cancer
This trial tests a new combination of immunotherapy (cadonilimab) and chemotherapy before and after surgery for a specific type of advanced stomach or gastroesophageal junction cancer. It aims to see if adding this immunotherapy helps shrink tumors and improve outcomes.
Lanzhou, GansuAges 18–75 - NCT07872722RecruitingPhase 2
Study of two immunotherapies plus chemotherapy before surgery for stomach cancer
This trial tests a new approach for stomach cancer that hasn't spread. You'd get a combination of an investigational drug targeting a specific protein on cancer cells, an immunotherapy that helps your immune system fight cancer, and standard chemotherapy before surgery. The goal is to see if this makes the tumor shrink more and improves outcomes.
SaitamaAges 18 years+ - NCT07142122Recruiting
Comparing two types of stomach surgery for early upper gastric cancer
This trial compares two laparoscopic surgeries for early-stage stomach cancer in the upper part of the stomach. It looks at whether preserving a nerve (celiac branch of vagus nerve) during surgery leads to better recovery while still removing the cancer safely.
Fuzhou, FujianAges 18–75 - NCT07034742RecruitingEarly Phase 1
MRD testing after stomach cancer surgery
This study looks at whether a blood test for leftover cancer cells (called MRD) after stomach cancer surgery can help guide treatment. It is for people with a certain type of stomach cancer that has spread to nearby tissues but not to distant organs, and who are having surgery as their first treatment.
BeijingAges 18–75 - NCT04840056Recruiting
Testing ways to predict stomach cancer risk
This trial looks at adults with stomach lining changes—either atrophic gastritis or intestinal metaplasia—and studies how to predict who may be at risk for stomach cancer. It may help earlier identification and closer monitoring for people with these conditions.
Shatin, New TerritoriesAges 18 years+ - NCT06364410RecruitingPhase 1
Testing a new drug combo for stomach and other solid tumors
This trial tests a combination of two drugs, trastuzumab deruxtecan and azenosertib, for people with stomach cancer or other solid tumors that have a specific protein called HER2. It aims to see if this combination can help when other treatments have stopped working.
Houston, TexasAges 18 years+ - NCT05107674RecruitingPhase 1
Early drug study for advanced cancers that have limited options
This Phase 1 study tests NX-1607 in adults with advanced cancers that are hard to treat with standard care. It focuses on safety and early signs of how well the drug may work in specific cancer types.
Duarte, CaliforniaAges 18 years+ - NCT05427383RecruitingPhase 2/Phase 3
KN026 plus chemo for HER2-positive stomach cancer after first treatment failure
This trial tests KN026 together with chemotherapy in people with HER2-positive advanced stomach (or gastro-esophageal junction) cancer that has already grown despite first-line treatment with trastuzumab plus chemotherapy. It may help by targeting HER2 while also using chemotherapy to control the cancer.
BeijingAges 18 years+ - NCT07770126Recruiting
Stomach bacteria study for gastric conditions and precancer
This study looks for certain stomach bacteria (other than the common H. pylori) that might be linked to stomach diseases or early signs of cancer. If you have a stomach condition, your participation could help doctors understand these bacteria better.
EdegemAges 18 years+ - NCT06451393Recruiting
AI predicts stomach cancer response to chemo
This trial tests a computer-based model that uses CT scans, endoscopic images, and biopsy tissue to predict how well stomach cancer will respond to chemotherapy given before surgery. The goal is to help doctors choose the best treatment for each patient.
Guangzhou, GuangdongAges 20–90 - NCT07849608Recruiting
AI Tool to Assess Tumor Response After Pre-Surgery Treatment
This study is testing an AI tool (DeepTRG) that looks at tissue samples after pre-surgery treatment to see how well the tumor responded. It may help doctors better understand whether the treatment worked.
Shijiazhuang, None SelectedAges 18 years+ - NCT01935778RecruitingPhase 3
Extra chemo after stomach cancer surgery: compare two drug plans
This Phase 3 trial tests which combination of chemotherapy works better after surgery for stage IIIB/IV stomach or stomach–esophagus junction adenocarcinoma. Participants get randomized to one of two chemotherapy plans to see which helps people live longer and/or prevents cancer from coming back.
SeoulAges 20–75
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Common questions
- Are there clinical trials for gastric (stomach) cancer?
- Yes. Clin2 currently lists 176 recruiting gastric (stomach) cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a gastric (stomach) cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a gastric (stomach) cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.