Clinical trials
General Population (no Specific Condition or Disease) clinical trials
Below are recruiting general population (no specific condition or disease) clinical trials, each written for real people, not researchers. We’re tracking 10,548 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT00001230Recruiting
Understanding How Your Body Responds to Filarial Infection
This study looks at how the body's immune system reacts to filarial infections—parasitic worms that affect millions worldwide. Researchers will observe your infection and response to treatment to better understand the disease and improve future care.
Bethesda, MarylandAges 3–100 - NCT00001215Enrolling by invitation
Understanding Genetic Lysosomal Storage Disorders
This study aims to understand genetic factors in lysosomal storage disorders—rare conditions where the body cannot break down certain substances. Researchers will collect information from patients with these disorders, their family members, and healthy volunteers to learn how these diseases develop and affect people over time.
Bethesda, MarylandAges 1 week–110 years - NCT00004847RecruitingPhase 1
Understanding and Diagnosing Pheochromocytoma and Paraganglioma
This study helps doctors better understand and diagnose pheochromocytoma and paraganglioma—rare tumors that release stress hormones and cause high blood pressure and other symptoms. Researchers will study your medical history, blood and urine tests, imaging scans, and genetic information to improve how these conditions are found and understood.
Bethesda, MarylandAges 3–120 - NCT00246857Recruiting
Screening study for inherited immune system conditions
This study screens people who may have an inherited immune system condition (like problems with immune cell growth or death) and their blood relatives. The goal is to understand the condition better by collecting blood samples for testing.
Bethesda, MarylandAges 1 month–100 years - NCT00557726Recruiting
Evaluation and care for inflammatory or infectious illnesses
This trial helps doctors evaluate possible infection or inflammation and decide on the best management plan. You may be able to receive specialized care at the NIH if the study team thinks your situation fits.
Bethesda, MarylandAges 3–100 - NCT00047996Enrolling by invitation
Blood Donation Study for Blood Vessel Research
This study collects blood and urine samples from adults to help researchers understand diseases affecting blood vessels. Your donation helps scientists develop better treatments.
Bethesda, MarylandAges 18–100 - NCT06855537RecruitingPhase 4
Treating unstable plaques that are not fully blocked
This trial compares treatments for heart patients who have a dangerous, but not fully blocking, fatty plaque in their arteries. It aims to see if treating these plaques with a stent or balloon can prevent future heart problems.
Beijing, Beijing MunicipalityAges 18–80 - NCT01193088Recruiting
Genetics study for Charcot-Marie-Tooth disease
This study looks at genes linked to Charcot-Marie-Tooth disease (CMT), a condition that affects nerves in the arms and legs. It aims to find new causes and understand why symptoms vary. If you join, you may give a blood or saliva sample for genetic testing.
Los Angeles, CaliforniaAges Any age - NCT07877090Recruiting
Brain activity during anesthesia in people with obesity
This study looks at how anesthesia affects brain waves in people with obesity compared to people with normal weight. It may help doctors understand if anesthesia needs to be adjusted for people with obesity.
Düzce, DüzceAges 18 years+ - NCT07085442Recruiting
Audit of targeted lymph node biopsy for early breast cancer
This study looks at how well a special type of lymph node biopsy works for people with early breast cancer that has spread to a small number of lymph nodes. It aims to see if this approach is effective and safe, which may help guide future treatment decisions.
BurnleyAges 18 years+ - NCT07444580RecruitingPhase 1
Gene-silencing drug for prion disease
This study tests a new drug that targets the genetic material causing prion disease, aiming to slow or stop the disease. It's for people with symptoms or those at high genetic risk, and involves regular check-ups and spinal taps.
Boston, MassachusettsAges 18 years+ - NCT07168993Recruiting
Sputum test for lung cancer in high-risk people with lung nodules
This study tests a new, non-invasive test that looks at a sputum (phlegm) sample to see if it can detect lung cancer in people who have a lung nodule. The test might help avoid more invasive procedures and help doctors decide next steps.
Palo Alto, CaliforniaAges 50–80 - NCT06292494Recruiting
Focused ultrasound for drug-resistant epilepsy
This trial tests a treatment called focused ultrasound, which uses sound waves to target and help control seizures in people whose epilepsy has not improved with at least two medications. It may offer a new option for those with localized epilepsy.
TaipeiAges 18 years+ - NCT07674277Recruiting
Virtual reality for pain relief in sickle cell crisis
This study tests whether using a virtual reality headset can help reduce pain for adults with sickle cell disease during a painful crisis. The trial aims to see if this non-drug approach can improve comfort while receiving IV pain medication.
Baltimore, MarylandAges 18–88 - NCT07878884Recruiting
Light therapy with lung rehab for severe COPD
This trial tests whether adding light therapy to a standard exercise program helps people with severe COPD breathe better and do more in their daily lives. It might be especially helpful if you have advanced COPD and can still walk.
Porto Alegre, Rio Grande do SulAges 18–90 - NCT07877272Recruiting
Better liver testing for high-risk fatty liver disease
This study tests a more detailed way to examine the liver in people with fatty liver disease who also have other health risks. The doctors want to see if this extra testing helps decide whether you need treatment.
MünsterAges 18 years+ - NCT07509034RecruitingPhase 1
Targeted immune cells for recurrent small cell lung cancer
This trial tests a special immune cell therapy (CAR T cells) that targets a protein called B7-H3 on your cancer cells. It is for people with small cell lung cancer or similar neuroendocrine cancers that have returned or not responded to standard treatments.
Bethesda, MarylandAges 18–120 - NCT00044122Recruiting
Study of mast cell growth in people with mastocytosis
This study looks at what causes mast cells to grow too much in people with mastocytosis. It may help researchers find better ways to diagnose or treat this condition. You can take part in person or by telehealth.
Bethesda, MarylandAges 1 day–80 years - NCT07744126RecruitingPhase 2
Combination drug therapy for head and neck cancer that has spread
This trial tests a new combination of two drugs (telisotuzumab adizutecan and pembrolizumab) for people with head and neck cancer that has come back or spread and cannot be cured with local treatments. The goal is to see if this combination can help control the cancer and to find the best dose.
Duarte, CaliforniaAges 18 years+ - NCT07721467RecruitingPhase 2
Cognitive training with psilocybin for brain flexibility
This study tests whether combining a brain-training program with a psychedelic drug called psilocybin can boost the brain's ability to change and adapt. It may help improve thinking and memory.
Baltimore, MarylandAges 65–120 - NCT05147701RecruitingPhase 1
Testing stem cell treatment for NAION safety
This Phase 1 study tests whether lab-made stem cells taken from donated umbilical cord are safe for people with NAION. It mainly looks for side effects and safety rather than proving the treatment works.
Naples, FloridaAges Any age - NCT03819803RecruitingPhase 3
Fecal transplant for gut graft-versus-host disease
This study tests whether restoring healthy gut bacteria using a fecal microbiota transplant can improve steroid-refractory gut graft-versus-host disease (aGvHD) after stem cell transplant. If your gut symptoms are your first episode and your stool bacteria diversity is low, this trial may be an option worth screening for.
Graz, StyriaAges 18–70 - NCT06894095Recruiting
Heart and blood vessel imaging study for adults with coronary CT
This study collects heart and blood vessel images from people who have already had a coronary CT scan. It aims to learn more about heart health and may help future patients.
Nanjing, JiangsuAges 18 years+ - NCT07775313Enrolling by invitationPhase 1/Phase 2
Gene therapy for WHIM syndrome
This trial tests a one-time gene therapy treatment for WHIM syndrome, a rare immune disorder. It aims to fix the genetic cause to improve your body's ability to fight infections. Your stem cells will be collected, edited in a lab, and given back to you after some chemotherapy to prepare your body.
Bethesda, MarylandAges 3–75
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Common questions
- Are there clinical trials for general population (no specific condition or disease)?
- Yes. Clin2 currently lists 10,548 recruiting general population (no specific condition or disease) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a general population (no specific condition or disease) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a general population (no specific condition or disease) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.