Clinical trials
General Population (no Specific Condition or Disease) clinical trials
Below are recruiting general population (no specific condition or disease) clinical trials, each written for real people, not researchers. We’re tracking 10,802 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04912739Recruiting
Targeted health conversations in primary care
This study offers targeted health dialogues with people receiving care in primary settings, to see how well these conversations can support health. You may be invited because of your age and where you receive healthcare in Skåne County.
Malmö, Skåne CountyAges 40–70 - NCT04911491Recruiting
Breathing muscle training for people with kidney disease
This study tests whether training your breathing muscles can improve health in people with chronic kidney disease (stage 3–4). It may help how your body handles daily activity and circulation-related measurements, compared with usual care.
Aurora, ColoradoAges 50 years+ - NCT04916132Recruiting
Diabetic kidney damage study using urine tests and biopsy
This study looks at how common diabetic kidney damage is in people with type 2 diabetes, and which factors can predict it. If you qualify, you may be asked to have a kidney biopsy to understand what’s happening inside your kidneys.
Skejby, AarhusAges 18–120 - NCT04920812Recruiting
Testing multi-sample methods to diagnose mitochondrial muscle disease
This study looks for the cause of suspected mitochondrial diseases by combining multiple lab tests on muscle and skin samples, plus genetic testing results. If your current gene tests didn’t find an answer, this could help researchers learn what might be causing your condition.
Nice, CHU de NICEAges Any age - NCT04924075RecruitingPhase 2
Belzutifan for cancers linked to VHL or HIF-2α changes
This Phase 2 study tests belzutifan (MK-6482) to treat certain advanced cancers caused by specific gene or disease changes, including VHL-related tumors and HIF-2α related tumors. It may help shrink tumors or slow their growth in people whose cancer matches these genetic or disease patterns.
Los Angeles, CaliforniaAges 12 years+ - NCT04924270RecruitingPhase 2
Capsule stool transfer for newly diagnosed inflammatory bowel or joint disease
This Phase 2 study tests whether taking capsule stool (FMT) is safe and can help people who are newly diagnosed and haven’t started the usual medicines yet. Participants will also start the standard first-line treatment for their condition, and the study will compare safety and outcomes.
OdenseAges 18–75 - NCT04927156Recruiting
Check safety and use of Balt medical devices after treatment
This post-marketing study follows people after they receive Balt medical devices to make sure the devices are safe, work well, and are easy to use in real life. You may be considered if you can consent and your procedure matches their device-use rules.
AngersAges 2 years+ - NCT04629547RecruitingPhase 2
Sleep study to help prevent Alzheimer’s disease
This trial tests whether treating sleep issues and measuring sleep can help lower the risk of Alzheimer’s disease before it starts. It focuses on older adults with no dementia signs yet.
St Louis, MissouriAges 65 years+ - NCT07697664Recruiting
Memory and thinking through exercise in aging
This study looks at whether light-to-moderate physical activity (like walking or stretching) can help memory and thinking in middle-aged and older adults. People with normal thinking, mild memory problems, or Parkinson's disease may join if they aren't already very active.
Atlanta, GeorgiaAges 18–79 - NCT05798923RecruitingPhase 2
LAM-001 for lung scarring with high blood pressure
This trial tests a new medication called LAM-001 for people with high blood pressure in the lungs caused by lung scarring. It aims to see if it can improve symptoms and help you feel better.
Tucson, ArizonaAges 18–80 - NCT07699614Recruiting
Lung health and germs in adults in Botswana
This study looks at how the lungs and tiny organisms in the body (microbiome) work together in adults living in Botswana. It may help doctors understand how to keep lungs healthier, especially for people with or without HIV.
GaboroneAges 35 years+ - NCT02437396Recruiting
Blood tests in stable adults with Gaucher disease
This study measures inflammation and “oxidative stress” (cell stress caused by imbalance in the body) using blood biomarkers in adults with Gaucher disease. It may help researchers understand what’s happening in the body and how treatment status relates to these blood signals.
Minneapolis, MinnesotaAges 18–75 - NCT06274528RecruitingPhase 2
DORA and lemborexant in Alzheimer's biomarkers study
This study is testing whether a sleep medication called lemborexant can improve sleep and reduce Alzheimer's-related proteins in healthy older adults with no memory problems. It could help find new ways to delay or prevent Alzheimer's disease.
St Louis, MissouriAges 65 years+ - NCT07698236Enrolling by invitation
Temporal interference brain stimulation for Parkinson's disease
This trial tests a new non-invasive brain stimulation method called temporal interference to see if it can improve symptoms of Parkinson's disease. It is for people aged 40 to 80 who are on stable Parkinson's medications and have mild to moderate symptoms.
ShanghaiAges 40–80 - NCT07599176RecruitingPhase 1/Phase 2
Partial stem cell transplant for sickle cell disease from matched donors
This study tests a partial stem cell transplant from a matched donor to treat sickle cell disease. It may help reduce complications like strokes, organ damage, or pain crises.
Bethesda, MarylandAges 4–65 - NCT06712654RecruitingPhase 2
Testing AP306 for high phosphate in dialysis patients
This trial tests a new medication called AP306 for people on hemodialysis who have high blood phosphate. It aims to see if the drug is safe, tolerable, and helps lower phosphate levels.
Huntsville, AlabamaAges 18 years+ - NCT07274254RecruitingPhase 3
Lidocaine to reduce opioid use for sickle cell pain crisis
This trial tests if adding lidocaine to standard pain treatment can reduce the amount of morphine or oxycodone needed for a severe pain crisis or acute chest syndrome in sickle cell disease. It is for adults in the ICU who have already started opioid treatment within the last 72 hours.
BordeauxAges 18 years+ - NCT07151378RecruitingPhase 3
Intestinal gel for Parkinson's mood and behavior problems
This trial tests a gel form of levodopa (called Lecigon) given through a tube into the intestine to see if it helps reduce mood swings, impulsive behaviors, and other mental side effects in people with Parkinson's who already have motor fluctuations. It is for people who have had Parkinson's for at least 5 years and are between 18 and 75 years old.
Saarlouis, SaarlandAges 18–75 - NCT04939207Recruiting
Test safer, cheaper scans for suspected coronary artery disease
This study compares new imaging methods to see how well they work and whether they can lower costs for people with suspected coronary artery disease. It may help by using different scan approaches while keeping patient safety in mind.
Eindhoven, North BrabantAges 18 years+ - NCT04939935RecruitingPhase 3
Metformin to slow kidney decline in adults with polycystic kidneys
This Phase 3 study tests whether taking metformin can slow the decline of kidney function in adults with autosomal dominant polycystic kidney disease (ADPKD). You may be eligible if you have ADPKD and signs that your kidneys are starting to decline faster than expected.
Gosford, New South WalesAges 18–70 - NCT04944940Recruiting
Study tests blood, scans, and genes in SBMA and healthy men
This study looks for early “biomarkers” (measurable signs) in the body using blood tests, imaging scans, and sometimes other procedures in men with genetically confirmed spinal and bulbar muscular atrophy (SBMA). The results may help future drug studies by showing better ways to track disease changes over time.
Bethesda, MarylandAges 18–120 - NCT04946721Recruiting
Study of eye-surface disease tests and targeted treatment
This study looks at how an “ocular surface” condition can be identified using tests (biomarkers) and how a targeted treatment may help. You may qualify if you’re an adult receiving eye care at specific University of Maryland locations.
Baltimore, MarylandAges 18 years+ - NCT04946916Recruiting
Testing blood/brain marker levels and thinking problems in psychiatric illness
This study looks at neurofilament light (a brain/nerve injury marker) and how it relates to thinking and memory problems in people with certain psychiatric conditions. It may help researchers understand brain changes and cognitive impairment, which could guide better diagnosis in the future.
BronAges 45–80 - NCT04950218Recruiting
Study risks of heart problems in people with psoriasis
This study asks adults with psoriasis about factors that may be linked to heart problems. It aims to better understand who is at higher risk, which could help guide future prevention and care.
Hellerup, CopenhagneAges 18 years+
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Common questions
- Are there clinical trials for general population (no specific condition or disease)?
- Yes. Clin2 currently lists 10,802 recruiting general population (no specific condition or disease) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a general population (no specific condition or disease) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a general population (no specific condition or disease) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.