Clinical trials
Generalized Anxiety clinical trials
Below are recruiting generalized anxiety clinical trials, each written for real people, not researchers. We’re tracking 100 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06853431RecruitingPhase 4
Pre-surgery calming medicine for children ages 1 to 6
This study tests a combination of two medicines (dexmedetomidine and esketamine) given as a nasal spray to help children relax before surgery. The goal is to find the best dose that works well with the least side effects.
Wenzhou, ZhejiangAges 1–6 - NCT07746505Recruiting
Remimazolam vs midazolam for anesthesia in older adults
This study compares two sedative medicines used to start general anesthesia in patients 65 and older having non-cardiac surgery. The goal is to see which one is safer and works better for older patients.
HangzhouAges 65 years+ - NCT05570812RecruitingPhase 2
Pregnenolone to improve depressed mood in people with HIV
This Phase 2 trial tests a brain-acting steroid called pregnenolone to help reduce depressed mood. It studies whether it can improve mood in adults with HIV who are already on HIV treatment and still have depression symptoms.
Boston, MassachusettsAges 18–85 - NCT06153121Recruiting
Arm and shoulder tests for healthy tennis players and swimmers
This study is for healthy tennis players and swimmers. It tests a set of physical performance tests for the upper body (arms, shoulders, hands) to see how well they measure athletic ability. If you are a competitive tennis player or swimmer and have no arm or shoulder problems, you may be eligible.
GhentAges 12–40 - NCT07292610Recruiting
Nut study for young university students
This trial tests whether eating nuts regularly can improve mental health in young adults. If you are a university student aged 18-25, you may be able to join.
Cuenca, CuencaAges 18–24 - NCT06226155Recruiting
HIV prevention support for pregnant women in Zimbabwe
This study in Zimbabwe tests a program to help pregnant women start and stay on PrEP (medication that prevents HIV). It aims to make PrEP easier to use during pregnancy for women who are at risk of HIV.
HarareAges 15–55 - NCT07323498Recruiting
Virtual reality treatment for public speaking fear
This study tests if virtual reality can help people who get very nervous giving speeches. You would practice speaking in a virtual setting to build confidence.
Marburg, HesseAges 18–70 - NCT06424392Recruiting
How lung surgery for birth defects affects kids long-term
This study follows children born with a congenital lung malformation (a lung problem present at birth) to see how surgery to remove it affects their breathing and emotional well-being over time. Your child might be eligible if they are already part of a large French research program called MALFPULM.
ParisAges 6–9 - NCT05916287Recruiting
STANISLAS cohort follow-up visit for heart and kidney health
This study is a follow-up visit for people who joined the STANISLAS family health cohort. Researchers look at how genes and environment may affect heart and kidney (kidneys) health over time.
Vandœuvre-lès-Nancy, LorraineAges Any age - NCT06557005Recruiting
Helping new mothers with chronic conditions get primary care
This study helps new mothers with chronic health conditions transition smoothly from pregnancy care to regular primary care. If you have high blood pressure, diabetes, severe obesity, depression, or anxiety, you may be able to join a program that coordinates your care after childbirth.
Boston, MassachusettsAges 18 years+ - NCT07091032Recruiting
Building connections for better health
This study tests if helping people address obesity, cancer screenings, or mental health struggles can improve their overall health. You may qualify if you have obesity, are behind on colon or cervical cancer screening, or have depression or anxiety.
Boston, MassachusettsAges 18–75 - NCT07153250Recruiting
Online parent training for young child anxiety
This trial tests an online program that teaches parents how to help their young child (ages 2 to 7) manage anxiety. You would complete the program at home, and researchers want to see if it reduces your child's anxiety symptoms.
Boston, MassachusettsAges 18 years+ - NCT06929442Recruiting
Prevention program for young adults with unusual experiences
This study tests a program to help young adults who have had unusual thoughts or experiences (like feeling people are talking about them or that things have hidden meanings) learn ways to cope and feel better. The goal is to prevent these experiences from turning into bigger problems.
Charlestown, MassachusettsAges 18–30 - NCT07007234Recruiting
Sedentary behavior and depression study
This study looks at how sitting or being inactive (sedentary behavior) affects depressive symptoms. If you have mild to severe depression, you may be able to join and help find out if moving more can improve your mood.
São Paulo, SOAges 18 years+ - NCT05699525Recruiting
Personalized app for cognitive behavioral therapy for young adults
This trial tests a mobile app that delivers personalized cognitive behavioral therapy (a structured talk-therapy approach that helps change unhelpful thoughts and behaviors). It may help reduce symptoms of anxiety, depression, or bipolar disorder for people who fit the study’s timing and safety requirements.
New York, New YorkAges 18–25 - NCT06726304Enrolling by invitation
Increasing physical contact for mothers with anxiety or depression
This study tests whether using a baby carrier more often helps mothers with anxiety or depression feel more connected to their babies. It is for mothers who had a healthy baby and were diagnosed with anxiety or depression during pregnancy.
Montreal, QuebecAges 18 years+ - NCT05962879Recruiting
Program for teens with early psychosis-like experiences
This trial tests a new mental health program for teenagers who are having at least one psychosis-like experience and may be at risk for serious mental illness. It may help by offering structured support for both teens and their parents.
Boston, MassachusettsAges 14–19 - NCT06108830Recruiting
Esketamine and remimazolam for better sleep after surgery
This study tests whether a combination of two medicines (esketamine and remimazolam) can help people sleep better and feel less anxious after surgery. Researchers want to see if this approach works better than standard care.
TianjinAges 20–65 - NCT05806112Enrolling by invitation
Improve staff well-being programs for residential care workers
This trial tests whether specific programs can reduce burnout and improve resiliency (coping strength) among staff who work in behavioral health group homes. It may help workers feel better and handle stressful work days.
Boston, MassachusettsAges 18 years+ - NCT06289621Recruiting
Brief treatment for anxiety and PTSD in South Africa
This trial tests a short, talk-based therapy for people with anxiety disorders or PTSD. It aims to help you manage symptoms in fewer sessions.
Cape TownAges 18–65 - NCT06640907Recruiting
Perinatal mental health support for expecting and new mothers
This trial tests a program that provides mental health support to pregnant women and new mothers through their usual healthcare visits. The goal is to see if offering this support as part of routine care can help prevent anxiety and depression.
Mairena del Aljarafe, SevilleAges 18 years+ - NCT07706244Recruiting
Does reducing pre-surgery anxiety help orthopedic patients recover better?
This study tests if a program to reduce anxiety before surgery (Enhanced Recovery After Surgery) improves how patients feel one year after major orthopedic surgery like knee, hip, or spine procedures, compared to standard care.
Hualien City, Hualien CountyAges 20–100 - NCT05765656Recruiting
Doctors and pharmacists helping older adults reduce sleeping pills
This study will see if working closely with your doctor and pharmacist can help older adults safely reduce or stop taking medications for anxiety or sleep, like benzodiazepines.
NantesAges 65 years+ - NCT07143357Recruiting
Mind-body recovery program for cardiac arrest survivors and their caregivers
This trial tests a mind-body program to help cardiac arrest survivors and their caregivers recover together after a cardiac arrest. It combines in-person and video sessions to reduce emotional distress and improve wellbeing.
Boston, MassachusettsAges 18 years+
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Common questions
- Are there clinical trials for generalized anxiety?
- Yes. Clin2 currently lists 100 recruiting generalized anxiety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a generalized anxiety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a generalized anxiety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.