Clinical trials
Glaucoma, Open-Angle clinical trials
Below are recruiting glaucoma, open-angle clinical trials, each written for real people, not researchers. We’re tracking 62 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07462000Recruiting
Eye fluid and tissue analysis in glaucoma and cataract
This study collects eye fluid and tissue samples during planned cataract or combined cataract-glaucoma surgery to analyze differences between people with and without glaucoma. It may help researchers understand eye disease better.
WarsawAges 18 years+ - NCT07662759RecruitingPhase 3
Study of TFC-003 for open-angle glaucoma or high eye pressure
This trial tests a new eye drop combination (TFC-003) to lower eye pressure in people with primary open-angle glaucoma or ocular hypertension. It compares the new drug to existing treatments to see if it works better or is safer.
SeongnamAges 19 years+ - NCT07480343Enrolling by invitation
Five-year follow-up after CREST glaucoma study
This study follows up with people who finished the CREST study to check how their eyes are doing 5 years later. It looks at the long-term results of a prior glaucoma treatment.
Newport Beach, CaliforniaAges Any age - NCT06925477Enrolling by invitation
New vs. standard laser for open-angle glaucoma
This study compares a new way of doing laser treatment for open-angle glaucoma versus the standard method. The goal is to see which approach works better at lowering eye pressure and protecting vision.
Charleston, South CarolinaAges 18 years+ - NCT05432245Enrolling by invitation
Glaucoma implant placed during cataract surgery
This trial looks at whether placing a small glaucoma implant at the same time as cataract surgery can better control eye pressure in people with primary open-angle glaucoma. It may help reduce the need for medicines or improve control, depending on how your eyes respond.
Panama CityAges 40 years+ - NCT05159960Enrolling by invitation
Repeat laser eye treatment study for eligible prior participants
This study is for people who already joined an earlier selective laser eye treatment trial and were able to be followed without needing stronger additional treatments. It looks at the best plan for repeating the laser treatment when appropriate.
Skövde, Västra Götaland CountyAges 18 years+ - NCT04381611Enrolling by invitation
Study of glaucoma surgeries and laser treatments over time
This study looks at people with glaucoma or high eye pressure to understand how surgeries and laser treatments affect long-term outcomes. It may help doctors predict which treatments work best for different patients.
Lausanne, Canton of VaudAges 1–100 - NCT07290244RecruitingPhase 1
Testing ER-100 safety for glaucoma or NAION patients
This trial tests whether a new drug, ER-100, is safe for people with glaucoma or a sudden optic nerve injury called NAION. It aims to see if the drug can be given without serious side effects.
Glendale, CaliforniaAges 40–85 - NCT06883123RecruitingPhase 4
Comparing two glaucoma drop combinations
This study compares two different pairs of glaucoma eye drops to see which works better. If you are currently using Cosopt and Latanoprost, you may be able to switch to Simbrinza and Rocklatan or stay on your current drops.
Springfield, IllinoisAges 18 years+ - NCT07400926Recruiting
Study of a new inserter for a glaucoma implant
This trial is testing a new way to deliver a medication (travoprost) directly into the eye using a small implant. It's for people with open-angle glaucoma and aims to see how well the updated inserter works.
Kenosha, WisconsinAges 18 years+ - NCT07661329RecruitingPhase 3
Comparing a new eye drop to a standard one for glaucoma and high eye pressure
This study tests a new eye drop against an existing one to see which better lowers eye pressure in people with open-angle glaucoma or ocular hypertension. You may be able to join if you have high eye pressure in both eyes that needs treatment and you are at least 18 years old.
Beverly Hills, CaliforniaAges 18 years+ - NCT07359547Recruiting
Comparing Two Glaucoma Drainage Devices
This trial compares two different tiny drainage devices (a gel stent and a microshunt) for lowering eye pressure in people with certain types of glaucoma that are not well controlled with medications. The goal is to see which device works better and is safer.
Leuven, Vlaams-brabantAges 40 years+ - NCT07496957Recruiting
A new glaucoma surgery: Preserflo versus trabeculectomy
This trial compares two types of glaucoma surgery to see which one works better for people with specific kinds of open-angle glaucoma whose eye pressure isn't controlled by eye drops or laser.
Bialystok, PolskaAges 21 years+ - NCT05163951Recruiting
Surgery comparison for advanced angle-closure glaucoma
This trial compares two types of glaucoma surgery—trabeculectomy versus a different procedure that also opens the drainage angle—for people with advanced primary angle-closure glaucoma. It aims to see which surgery controls eye pressure and preserves vision better.
Guangzhou, GuangdongAges 45–80
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Common questions
- Are there clinical trials for glaucoma, open-angle?
- Yes. Clin2 currently lists 62 recruiting glaucoma, open-angle studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a glaucoma, open-angle trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a glaucoma, open-angle trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.