Clinical trials
Open Heart Surgery clinical trials
Below are recruiting open heart surgery clinical trials, each written for real people, not researchers. We’re tracking 36 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06707454Recruiting
Recovery after open heart surgery in older adults
This study looks at how older adults recover after open heart surgery, focusing on brain and nerve health. It may help researchers understand the effects of surgery on thinking and memory.
CairoAges 60 years+ - NCT05927233RecruitingPhase 4
Methylprednisolone in children after open-heart surgery
This trial tests whether giving methylprednisolone (a steroid medicine) can lower the body’s inflammatory response in children during the first day after congenital open-heart surgery. It may help reduce harmful inflammation and improve recovery for some children undergoing their first surgery.
Karachi, SindhAges 1 month–18 years - NCT07040735Recruiting
Low-flow anesthesia study for open-heart surgery
This study tests a low-flow anesthesia method during open-heart surgery to see if it works well and safely. It may help patients by using less medication.
AnkaraAges 18 years+ - NCT06551714Recruiting
Movement techniques after first open heart surgery
This study tests special movement and breathing techniques to help people recover faster after their first open heart surgery. It focuses on improving health in the early days after surgery.
AnkaraAges 18–75 - NCT07037485Recruiting
Predicting kidney injury after open heart surgery
This trial tests if kidney ultrasound and urine oxygen levels can predict acute kidney injury after open heart surgery. It aims to help doctors catch kidney problems early.
Tanta, El-GharbiaAges 21 years+ - NCT07257744Recruiting
Pain management after open heart surgery: comparing three methods
This trial compares three ways to manage pain after open heart surgery to see which best prevents long-term chronic pain. It may help you decide with your doctor which pain control option is right for you.
Trabzon, TrabzonAges 18–85 - NCT06616129Recruiting
Geriatric risk assessment for older heart surgery patients
This study tests whether a special geriatric risk assessment and shared decision-making conversation helps older patients (70+) and their doctors choose the best treatment for heart surgery. It aims to improve quality of life by tailoring decisions to each person's health risks.
Groningen, Provincie GroningenAges 70 years+ - NCT07314996Recruiting
Laparoscopic vs. open surgery for colon cancer with belly fat
This trial compares laparoscopy (minimally invasive) and open surgery for treating colon cancer in people with extra belly fat around internal organs (visceral obesity). The goal is to see which approach gives better recovery and outcomes.
Hangzhou, ZhejiangAges 18–75 - NCT06623578Recruiting
Robotic vs. open surgery for thyroid cancer that has spread
This study compares a robotic surgery method using small incisions under the armpit with standard open surgery for papillary thyroid cancer that has spread to lymph nodes on one side of the neck. It aims to see which approach is better for removing cancer and recovery.
Guangzhou, GuangdongAges 18–70 - NCT07477977Recruiting
Finding the right dose of protamine to reverse heparin after heart bypass
This study is testing different doses of a medication called protamine, which is given after heart surgery to reverse the effects of heparin (a blood thinner). The goal is to find the safest and most effective dose for patients who have had a heart-lung bypass machine during surgery.
SohagAges 18 years+ - NCT06233318Recruiting
Pain block for open heart surgery recovery
This study tests a nerve block given during open heart surgery to improve pain control. It might help patients recover with less discomfort.
Columbus, OhioAges 18 years+ - NCT06828432Enrolling by invitation
Device study for heart surgery patients in the heart intensive care unit
This trial tests a new device that measures heart function closely after heart surgery. It may help doctors give better care if you are in the heart intensive care unit after your operation.
Pittsburgh, PennsylvaniaAges 18–105 - NCT07591987Recruiting
Breathing Techniques to Reduce Shortness of Breath After Heart Surgery
This study tests whether special breathing exercises can help reduce shortness of breath and improve heart and lung function in patients recovering from open-heart surgery. You would learn and practice these breathing techniques before and after your surgery.
Baghdad, Baghdad GovernorateAges 18–75 - NCT07665593Recruiting
AI breathing training after open heart surgery
This trial tests if an AI-assisted breathing exercise device can reduce pain, fatigue, and improve breathing in patients recovering from open heart surgery.
Kocaeli, İzmitAges 18 years+ - NCT06997419Recruiting
Dexamethasone for nausea after open surgery
This trial tests if a steroid called dexamethasone palmitate can prevent nausea and vomiting after open surgery. It is for people having planned spine, chest, or abdominal surgery under general anesthesia.
BeijingAges 18–65 - NCT07059689Recruiting
Comparing breathing support after heart surgery in children
This trial compares two types of breathing support (high-flow nasal cannula vs. non-invasive ventilation) in children who have recently had heart surgery and are at high risk of having trouble breathing after their breathing tube is removed. The goal is to see which method works better to help them breathe on their own.
Jakarta, DKI JakartaAges Up to 18 years - NCT06493227Recruiting
Extended use of bleeding control drugs after heart surgery
This trial is for hospitals, not patients. Hospitals that do many open heart surgeries and whose doctors agree to use certain bleeding control drugs (fibrinolysis inhibitors) as per the study protocol can participate.
Saint PetersburgAges 18 years+ - NCT06534372Recruiting
Factors affecting chronic pain after open-heart surgery
This study looks at factors that may lead to long-term pain after open-heart surgery. It follows patients who have coronary bypass or valve surgery to understand what might cause ongoing pain.
Ankara, AnkaraAges 18–80 - NCT07163858Recruiting
Leg raising vs. medication for heart bypass surgery
This trial compares a simple leg-raising technique to a medicine (noradrenaline) to help keep blood pressure stable during heart bypass surgery. It may help you avoid stronger drugs and have a smoother recovery.
Caluire-et-Cuire, Auvergne-Rhône-AlpesAges 18 years+ - NCT07172620Recruiting
Heart bypass surgery without clamping the aorta
This study tests a special technique for heart bypass surgery that avoids clamping the aorta. It may help people with hardened arteries in the aorta who need bypass surgery but are not good candidates for standard clamping.
Beijing, Beijing MunicipalityAges Any age - NCT03849443RecruitingEarly Phase 1
Testing tranexamic acid to reduce bleeding after spine fusion
This trial studies whether a single dose or multiple doses of tranexamic acid (TXA) can reduce the chance you need a blood transfusion after spine fusion surgery. It also compares two different ways TXA may be given (by mouth and through a vein) to see which approach works best and is safe.
Chicago, IllinoisAges 18 years+ - NCT06725030Recruiting
Robotic surgery for lymphedema (Symani System)
This trial uses a robotic arm called Symani to help surgeons perform more precise microsurgery (working on tiny blood vessels and lymph channels). It is for adults with moderate lymphedema in one arm or leg who have already tried standard lymphedema therapy and still have swelling.
Beverly Hills, CaliforniaAges 22 years+ - NCT07510451Recruiting
Predicting low blood pressure during major aortic surgery
This trial tests a new monitoring tool that predicts drops in blood pressure before they happen during major aortic surgery. It may help doctors keep your blood pressure more stable during the procedure.
Poznan, PoznańAges 18 years+ - NCT07413965Recruiting
Transcatheter vs surgical valve replacement for severe bicuspid aortic stenosis
This trial compares two ways to replace a narrowed heart valve in people with a bicuspid aortic valve. If you're 50 or older and need a new valve, this study can help figure out which approach works best.
Los Angeles, CaliforniaAges 50 years+
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Common questions
- Are there clinical trials for open heart surgery?
- Yes. Clin2 currently lists 36 recruiting open heart surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a open heart surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a open heart surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.