Clinical trials
Primary Open Angle Glaucoma clinical trials
Below are recruiting primary open angle glaucoma clinical trials, each written for real people, not researchers. We’re tracking 57 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05844384Recruiting
Testing a new eye drop bottle for glaucoma
This study checks whether a device called the Nanodropper helps deliver glaucoma medicine as well as standard use. It is for adults with stable primary open-angle glaucoma (or ocular hypertension) who are on a limited number of eye-pressure medicines.
Lackland Air Force Base, TexasAges 18 years+ - NCT06057051Recruiting
Stent implant for mild to moderate open-angle glaucoma
This trial studies a tiny implant called iStent Infinite that helps drain fluid from the eye to lower pressure in people with mild to moderate open-angle glaucoma. It may offer a new way to manage the condition.
Cincinnati, OhioAges 35 years+ - NCT05710198RecruitingPhase 3
Citicoline eye drops to slow vision field loss in glaucoma
This Phase 3 trial tests whether citicoline 2% eye drops can help slow worsening of the visual field in adults with open-angle glaucoma. If you qualify, you would be monitored with repeated eye tests to see if your vision field stays more stable over time.
Milan, MIAges 18 years+ - NCT07777861RecruitingPhase 2
Testing an eye drop for worsening glaucoma
This study tests an eye drop (G01) for people with primary open-angle glaucoma that is getting worse despite current treatments. It aims to see if G01 can safely slow down or stop the progression of glaucoma.
Beijing, Beijing MunicipalityAges 18–80 - NCT07700498Recruiting
Combined cataract and glaucoma surgery for new patients
This trial tests a single surgery to treat both glaucoma and cataracts at the same time. It is for people who have not had any prior glaucoma treatment and need cataract surgery.
Ningxia, NingxiaAges 40–85 - NCT05039684Recruiting
Testing eye-surface inflammation in glaucoma or high eye pressure
This study measures inflammation markers on the eye surface in people with primary open-angle glaucoma or ocular hypertension who use certain glaucoma drops. The results may help doctors understand how these drops affect the eye and inflammation.
ValladolidAges 18–99 - NCT07675824RecruitingPhase 1/Phase 2
New treatment for open-angle glaucoma or high eye pressure
This trial tests an investigational drug called REGN22530 for people with mild to moderate primary open-angle glaucoma or ocular hypertension (high eye pressure). The goal is to see if it can safely lower eye pressure and protect vision.
Deerfield Beach, FloridaAges 18 years+ - NCT07661329RecruitingPhase 3
Comparing a new eye drop to a standard one for glaucoma and high eye pressure
This study tests a new eye drop against an existing one to see which better lowers eye pressure in people with open-angle glaucoma or ocular hypertension. You may be able to join if you have high eye pressure in both eyes that needs treatment and you are at least 18 years old.
Beverly Hills, CaliforniaAges 18 years+ - NCT07662759RecruitingPhase 3
Study of TFC-003 for open-angle glaucoma or high eye pressure
This trial tests a new eye drop combination (TFC-003) to lower eye pressure in people with primary open-angle glaucoma or ocular hypertension. It compares the new drug to existing treatments to see if it works better or is safer.
SeongnamAges 19 years+ - NCT07619482Enrolling by invitationPhase 1/Phase 2
Insulin eye drops for glaucoma
This study tests whether insulin eye drops can help people with glaucoma by protecting the optic nerve. It is an early-stage trial that may offer a new way to manage the condition.
Palo Alto, CaliforniaAges 18–90 - NCT07599241Recruiting
Exercise Program for Older Women With Thyroid, Eye, and Liver Conditions
This study tests whether a physical activity program can help older women manage three common conditions together: an underactive thyroid, high eye pressure (glaucoma), and fatty liver disease. Researchers want to see if exercise improves symptoms and overall health when addressing multiple conditions at once.
Dokki, Giza GovernorateAges 65–75 - NCT07523139Recruiting
Eye Structure Study in Angle-Closure Glaucoma
This research study uses ultrasound imaging to examine the internal structures of the eye in people with angle-closure glaucoma (a type of increased eye pressure) and compares them to healthy eyes. Understanding these structures may help doctors better diagnose and treat this eye condition.
BeijingAges 30–79 - NCT06792422RecruitingPhase 4
Oral semaglutide for open-angle glaucoma
This trial tests if an oral medication called semaglutide can help people with open-angle glaucoma. It aims to see if it can protect the optic nerve and manage eye pressure.
Glostrup MunicipalityAges 45 years+ - NCT07454447Recruiting
Eye exam after new glaucoma surgery
This trial uses a special ultrasound to look at the eye after a certain type of glaucoma surgery. It helps doctors see how well the surgery is working for people with open-angle glaucoma.
Minya, Minya GovernorateAges Any age - NCT07462000Recruiting
Eye fluid and tissue analysis in glaucoma and cataract
This study collects eye fluid and tissue samples during planned cataract or combined cataract-glaucoma surgery to analyze differences between people with and without glaucoma. It may help researchers understand eye disease better.
WarsawAges 18 years+ - NCT07447011Recruiting
Glaucoma treatment response with sleep apnea lifestyle changes
This trial tests whether lifestyle changes can help open-angle glaucoma in people who also have obstructive sleep apnea and are obese. It may offer a non-drug way to manage both conditions.
Giza, DokkiAges 30–50 - NCT07390890Recruiting
DSLT to reduce glaucoma eye drops
This trial is testing a laser treatment called DSLT to see if it can help people with glaucoma use fewer eye drops. It may be a good option if your eye pressure is already controlled with medication and you haven't had glaucoma surgery before.
Largo, FloridaAges Any age - NCT07358650Recruiting
MIST device for lowering eye pressure in glaucoma
This study tests a new device called MIST that is placed inside the eye to help lower eye pressure in people with primary open-angle glaucoma. It may be an option for those whose pressure is still too high despite using eye drops.
Dieppe, New BrunswickAges 40 years+ - NCT07335211RecruitingPhase 3
Testing a new eye drop for glaucoma or high eye pressure
This trial tests a new medicine called HUC3-637 for people with primary open-angle glaucoma or ocular hypertension. It aims to see if it safely lowers eye pressure.
SeoulAges 19 years+ - NCT06865235Recruiting
Glaucoma and cataract surgery with a new device
This trial tests a surgery that combines cataract removal with a new technique to lower eye pressure in people who have both primary open-angle glaucoma and cataracts. It aims to see if this combined surgery is safe and effective.
Belo Horizonte, Minas GeraisAges 40 years+ - NCT07322965Recruiting
Citicoline and DHA supplement for glaucoma patients
This trial tests whether a dietary supplement (DHA + citicoline) can help protect vision in people with glaucoma. You may qualify if you have confirmed glaucoma in at least one eye and are between 50 and 75 years old.
Barcelona, BarcelonaAges 50–75 - NCT07310719Recruiting
Comparing laser versus eye drops for new glaucoma patients
This trial compares two first treatments—laser therapy (SLT) or daily eye drops (latanoprost)—to lower eye pressure in people newly diagnosed with open-angle glaucoma or high eye pressure. It aims to find which approach works better as an initial therapy.
Ikeja, LagosAges 18–90 - NCT06523751Recruiting
Predicting success of a glaucoma surgery with a quick test
This study tests a new quick procedure called trabeculopuncture to see if it can predict whether a more involved glaucoma surgery (ab interno trabeculectomy) will work for you. If you have a specific type of glaucoma, high eye pressure despite drops, and need cataract surgery, this trial might help lower your pressure and reduce medications.
Würzburg, BavariaAges 18 years+ - NCT07235592Recruiting
Preserflo MicroShunt study for open-angle glaucoma
This trial is testing a small device called the PRESERFLO MicroShunt to lower eye pressure in people with open-angle glaucoma. It may be an option if your eye pressure stays high even with maximum eye drops.
ViennaAges 18–85
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Primary Open Angle Glaucoma trials by city
Studies with a site in or near these metro areas.
Primary Open Angle Glaucoma trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for primary open angle glaucoma?
- Yes. Clin2 currently lists 57 recruiting primary open angle glaucoma studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a primary open angle glaucoma trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a primary open angle glaucoma trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.