Clinical trials
Primary Angle-Closure Glaucoma clinical trials
Below are recruiting primary angle-closure glaucoma clinical trials, each written for real people, not researchers. We’re tracking 21 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06822738RecruitingPhase 3
Study of XEN63 gel stent for glaucoma patients
This trial tests a new gel stent (XEN63) to lower eye pressure in adults with glaucoma. It compares two ways of putting the stent in the eye, and may help people who have not had success with other treatments.
Glendale, ArizonaAges 45 years+ - NCT03423758Recruiting
Genetic study of eye diseases: PXF, angle-closure and open glaucoma
This study looks at blood or DNA-related factors that may explain why certain glaucoma and related eye conditions happen. It may help researchers understand risk and causes across different glaucoma types.
ViennaAges 21–105 - NCT07700498Recruiting
Combined cataract and glaucoma surgery for new patients
This trial tests a single surgery to treat both glaucoma and cataracts at the same time. It is for people who have not had any prior glaucoma treatment and need cataract surgery.
Ningxia, NingxiaAges 40–85 - NCT05163951Recruiting
Surgery comparison for advanced angle-closure glaucoma
This trial compares two types of glaucoma surgery—trabeculectomy versus a different procedure that also opens the drainage angle—for people with advanced primary angle-closure glaucoma. It aims to see which surgery controls eye pressure and preserves vision better.
Guangzhou, GuangdongAges 45–80 - NCT05563623Recruiting
Study of people at risk for angle-closure progression
This study follows people who have eye anatomy that suggests a higher risk of angle closure, but who do not currently have high eye pressure or glaucoma damage. It aims to understand how often and how fast this risk can progress, which may help guide earlier monitoring or prevention.
Beijing, BeeijingAges 40–75 - NCT06057051Recruiting
Stent implant for mild to moderate open-angle glaucoma
This trial studies a tiny implant called iStent Infinite that helps drain fluid from the eye to lower pressure in people with mild to moderate open-angle glaucoma. It may offer a new way to manage the condition.
Cincinnati, OhioAges 35 years+ - NCT06952153Recruiting
Comparing two surgeries for glaucoma with cataract
This trial compares two types of eye surgery—one that removes the cataract and opens blocked drainage channels, and another that creates a new drainage pathway. It aims to find which works better for people with both glaucoma and cataracts.
Ho Chi Minh CityAges 40 years+ - NCT07076303Recruiting
Laser treatment for new glaucoma patients without prior medication
This study tests a new laser treatment called DSLT for people who have just been diagnosed with open-angle glaucoma or a similar condition like ocular hypertension. It aims to see if the laser can lower eye pressure by at least 20% after six months without needing any eye drops.
Plymouth Meeting, PennsylvaniaAges 18 years+ - NCT07147647Recruiting
Laser treatment for lowering eye pressure in Black patients with glaucoma
This trial tests a laser procedure called DSLT to reduce eye pressure in Black patients with mild to moderate open-angle glaucoma. It aims to see if this treatment works well as a first step before using eye drops.
Elkridge, MarylandAges 18 years+ - NCT07335211RecruitingPhase 3
Testing a new eye drop for glaucoma or high eye pressure
This trial tests a new medicine called HUC3-637 for people with primary open-angle glaucoma or ocular hypertension. It aims to see if it safely lowers eye pressure.
SeoulAges 19 years+ - NCT07358650Recruiting
MIST device for lowering eye pressure in glaucoma
This study tests a new device called MIST that is placed inside the eye to help lower eye pressure in people with primary open-angle glaucoma. It may be an option for those whose pressure is still too high despite using eye drops.
Dieppe, New BrunswickAges 40 years+ - NCT07390890Recruiting
DSLT to reduce glaucoma eye drops
This trial is testing a laser treatment called DSLT to see if it can help people with glaucoma use fewer eye drops. It may be a good option if your eye pressure is already controlled with medication and you haven't had glaucoma surgery before.
Largo, FloridaAges Any age - NCT07454447Recruiting
Eye exam after new glaucoma surgery
This trial uses a special ultrasound to look at the eye after a certain type of glaucoma surgery. It helps doctors see how well the surgery is working for people with open-angle glaucoma.
Minya, Minya GovernorateAges Any age - NCT07517302Recruiting
Dual Blade Surgery for Angle-Closure Glaucoma With Cataracts
This trial tests a new surgical technique called Kahook Dual Blade goniotomy combined with cataract removal in patients with chronic angle-closure glaucoma—a condition where fluid pressure builds up in the eye because drainage channels are blocked. The goal is to lower eye pressure and help preserve vision.
BeijingAges 40 years+ - NCT07523139Recruiting
Eye Structure Study in Angle-Closure Glaucoma
This research study uses ultrasound imaging to examine the internal structures of the eye in people with angle-closure glaucoma (a type of increased eye pressure) and compares them to healthy eyes. Understanding these structures may help doctors better diagnose and treat this eye condition.
BeijingAges 30–79 - NCT07539675Recruiting
Eye protein changes in angle-closure glaucoma
This study examines how proteins in the eye lens support structures change in patients with angle-closure glaucoma. Researchers will compare these proteins in people with glaucoma who have loose or normal support structures during surgery, and in people without glaucoma having cataract surgery.
Wuhan, HubeiAges 50 years+ - NCT04381611Enrolling by invitation
Study of glaucoma surgeries and laser treatments over time
This study looks at people with glaucoma or high eye pressure to understand how surgeries and laser treatments affect long-term outcomes. It may help doctors predict which treatments work best for different patients.
Lausanne, Canton of VaudAges 1–100 - NCT07462000Recruiting
Eye fluid and tissue analysis in glaucoma and cataract
This study collects eye fluid and tissue samples during planned cataract or combined cataract-glaucoma surgery to analyze differences between people with and without glaucoma. It may help researchers understand eye disease better.
WarsawAges 18 years+ - NCT07777861RecruitingPhase 2
Testing an eye drop for worsening glaucoma
This study tests an eye drop (G01) for people with primary open-angle glaucoma that is getting worse despite current treatments. It aims to see if G01 can safely slow down or stop the progression of glaucoma.
Beijing, Beijing MunicipalityAges 18–80 - NCT06523751Recruiting
Predicting success of a glaucoma surgery with a quick test
This study tests a new quick procedure called trabeculopuncture to see if it can predict whether a more involved glaucoma surgery (ab interno trabeculectomy) will work for you. If you have a specific type of glaucoma, high eye pressure despite drops, and need cataract surgery, this trial might help lower your pressure and reduce medications.
Würzburg, BavariaAges 18 years+ - NCT06201455Recruiting
Glaucoma surgery study for people with controlled eye pressure and cataracts
This study tests a new surgery that combines cataract removal with a glaucoma procedure to lower eye pressure in people with primary open-angle glaucoma. It's for people whose eye pressure is controlled with 1 to 4 medications but who also have significant cataracts.
Guangzhou, GuangdongAges 40–85
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Common questions
- Are there clinical trials for primary angle-closure glaucoma?
- Yes. Clin2 currently lists 21 recruiting primary angle-closure glaucoma studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a primary angle-closure glaucoma trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a primary angle-closure glaucoma trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.