Clinical trials
Gut Health clinical trials
Below are recruiting gut health clinical trials, each written for real people, not researchers. We’re tracking 85 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06588218Recruiting
Watermelon for gut and heart health in young adults
This study is testing whether eating watermelon every day for 4 weeks can improve gut health and heart health in young adults. If you are overweight and between 18 and 30, you may be able to join.
Tallahassee, FloridaAges 18–30 - NCT06916936Recruiting
Peanut butter study for gut health in kids
This study tests if eating peanut butter every day for a few weeks can improve how your body digests food and stays healthy. It's for kids in elementary or middle school who don't have nut allergies or certain stomach problems.
Tallahassee, FloridaAges 6–13 - NCT07095426Recruiting
Fiber supplement study for gut and blood vessel health
This study tests whether taking a fiber supplement can improve gut health and blood vessel health in people with obesity. It may help you understand how your body responds to extra fiber.
Muncie, IndianaAges 18–55 - NCT07460856Recruiting
Can Cranberries Improve Your Gut and Metabolic Health?
This study tests if eating cranberries can improve your gut health and metabolism. It’s for people who are overweight and have early signs of metabolic problems, like high blood sugar or high triglycerides.
Québec, QuebecAges 25–70 - NCT06735651Recruiting
Wild blueberries for gut, brain, and heart health in prediabetes
This study looks at whether eating wild blueberries can improve your gut health, brain function, and heart health if you have prediabetes. It may help lower your blood sugar and reduce your risk for diabetes and heart disease.
Atlanta, GeorgiaAges 20–65 - NCT06735599Recruiting
Wild blueberries for blood pressure health
This study tests whether eating wild blueberries can improve your gut, brain, and heart health if you have high blood pressure. You'll eat blueberries daily for several weeks and have checkups to see how your body responds.
Atlanta, GeorgiaAges 45–65 - NCT04117321Recruiting
Study of mother-to-baby gut germs and baby health
This study looks at how germs in a mother can be passed to her baby and whether that affects the baby’s health. If you join, your baby (and the other parent or legal guardian) may be asked to share consent so researchers can follow the pregnancy and early life.
Hong Kong, Hong KongAges Any age - NCT06544915Recruiting
Synbiotic vs. probiotic for heart and gut health
This study tests whether a synbiotic (a combination of probiotics and prebiotics) is better than a probiotic alone or a placebo for improving gut health and heart health. If you are a healthy adult who hasn't taken antibiotics recently and has few heart disease risk factors, you may be able to join.
Saratoga Springs, New YorkAges 18–60 - NCT07457723RecruitingPhase 2
Gut health and metabolism study
This study tests whether a supplement can improve metabolic health by changing the bacteria in your gut. It looks at how your body processes food and energy.
Brisbane, QueenslandAges 18 years+ - NCT06265246Recruiting
Milk and yogurt for stronger bones in young adults
This study tests whether adding milk and yogurt to your diet can improve bone health and body composition. If you're a young adult with low calcium intake, you may qualify to join.
Saskatoon, SaskatchewanAges 19–30 - NCT06329544Recruiting
Study of a high-fructose diet and gut health
This trial tests how a high-fructose diet affects your gut bacteria and overall metabolic health. It is for people who already know they don't absorb fructose well (fructose malabsorbers) and want to understand how this sugar impacts their body.
New York, New YorkAges 25–45 - NCT06546020Recruiting
Haskap berries for gut and metabolic health
This study tests whether a berry called Haskap can improve your gut health and how that might affect your overall health. Researchers are looking for people with and without certain metabolic risk factors to see who benefits most from adding these berries to their diet.
Bozeman, MontanaAges 35–65 - NCT07093346Recruiting
Pectin supplement for fatty liver disease
This study tests whether a pectin supplement (a fiber found in fruits) can reduce inflammation and improve liver and metabolic health in people with fatty liver disease (MASLD). You might be eligible if you have MASLD, a healthy weight range, and can avoid certain medications and foods.
NottinghamAges 18 years+ - NCT07559227Recruiting
How obesity affects gut health and blood vessel function
This study compares people with normal weight to people with obesity who are otherwise healthy to understand how body weight affects gut bacteria, immune function, and blood vessel health. Results may help explain why some people with obesity stay healthier than others.
Muncie, IndianaAges 18–55 - NCT07754721Recruiting
Diet and lifestyle program for chronic acid reflux
This study tests a comprehensive program that combines diet and lifestyle changes to help people with chronic acid reflux (heartburn, acid regurgitation, or chest pain) feel better. It looks at how these changes can improve your overall health and reduce symptoms.
Hualien City, TaiwanAges 18–79 - NCT06606678Enrolling by invitation
Physical activity for better metabolism and health
This study looks at how regular exercise can help improve your metabolism, lower inflammation, and support your gut health. If you're over 50 and can safely be active, this trial may be a good fit.
PoznanAges 50 years+ - NCT07592975Recruiting
Food with Fiber and B-Vitamins for Gut Health in Older Adults
This study tests whether adding special fibers (prebiotics) and B-vitamins to food can improve your gut bacteria, reduce inflammation, and support mental health. You'll eat fortified foods for several weeks while researchers track changes in your digestion and wellbeing.
Coleraine, County LondonderryAges 50 years+ - NCT07497711RecruitingPhase 2/Phase 3
Virtual treatment for menstrual cramps
This study tests a virtual (app-based) approach to help manage menstrual cramps. It is for people with regular periods who have moderate to severe cramp pain and want to try a non-medication option.
SingaporeAges 16–35 - NCT07636850Recruiting
How almonds affect gut bacteria in children
This study looks at whether eating almonds changes the helpful bacteria in kids' stomachs and intestines. Researchers will give some children almonds to eat and study how it affects their digestive health.
Tallahassee, FloridaAges 6–13 - NCT07195006Recruiting
Malnutrition in pregnancy and child growth study
This study looks at how nutrition during pregnancy affects the health of mothers and babies, including gut health and growth. It compares women with low nutrition to those with healthy nutrition.
HarareAges 18 years+ - NCT07300553RecruitingPhase 2
Gut bacteria and energy metabolism in health and IBD
This study looks at how the bacteria living in your gut affect your body's energy use. It includes both healthy volunteers and people with inactive Crohn's disease or ulcerative colitis.
ParisAges 18–50 - NCT06136793Enrolling by invitation
Healthy home habits for Chinese-heritage adults
This study tests a program to help Chinese-heritage adults with heart or diabetes conditions adopt healthier eating and lifestyle habits at home. It includes online resources and support to make lasting changes.
New Brunswick, New JerseyAges 30–70 - NCT05623007Recruiting
Diet and gut bacteria study for vaccinated teens with COVID
This trial tests whether changing diet can shift gut bacteria in overweight or obese teens after COVID-19 vaccination. The goal is to see if dietary changes can affect health markers related to the gut and immune system.
Jakarta Pusat, DKI JakartaAges 12–17 - NCT06051318Recruiting
Diet and gut microbiome effects on blood sugar in healthy adults
This study looks at how your gut bacteria and the foods you eat affect your blood sugar after meals. You'll wear a small sensor to track your blood sugar for 10 days and provide stool samples.
Florianópolis, Santa CatarinaAges 18–60
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Common questions
- Are there clinical trials for gut health?
- Yes. Clin2 currently lists 85 recruiting gut health studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a gut health trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a gut health trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.