Clinical trials
Headache Disorders clinical trials
Below are recruiting headache disorders clinical trials, each written for real people, not researchers. We’re tracking 29 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07754266Recruiting
Headache, ear, and dizziness registry
This study collects information from people who have headaches, ear problems, dizziness, or sinus issues to better understand these symptoms and how they relate to migraine. Your participation may help improve future treatments and diagnosis.
North Kingstown, Rhode IslandAges 18 years+ - NCT04715685Recruiting
Mind-body balance program for children with migraine
This trial studies a mind-body balance approach to help reduce symptoms and disability from pediatric migraine. You may join if your child has migraine headaches and can follow study routines, including keeping a headache diary.
Aurora, ColoradoAges 10–17 - NCT04939922Recruiting
Headache and dizziness registry for people with headache disorders
This study is a registry, meaning it collects information over time about people with headaches (including migraine, tension-type, and some dizziness-related headaches). It may help researchers better understand these conditions and plan future studies.
Hangzhou, ZhejiangAges 4–99 - NCT05418218Recruiting
International headache registry for people with headache diagnoses
This study collects information from people who have headaches to better understand different headache types. You may help researchers by keeping headache records and allowing follow-up over time.
Hangzhou, ZhejiangAges 4–99 - NCT05889624Recruiting
Study of treatments for childhood migraine headaches
This study looks at ways to help children and teens with migraine headaches by testing a care approach that includes access to evidence-based treatment. It may help if your child has frequent migraine headaches and is starting (or not already on) certain migraine-preventive medicines.
Birmingham, AlabamaAges 10–17 - NCT05334927Recruiting
Headache disorder registry for teens and adults with primary headaches
This study is a headache disorder registry that enrolls people with common, “primary” headache types such as migraine or tension headache, including some with medication-overuse headaches. It collects information to better understand these conditions and who they affect.
Anqing, AnhuiAges 12 years+ - NCT06716489Recruiting
Exercise study for women with migraine
This study tests whether aerobic exercise can help reduce migraine symptoms and improve how your body senses and responds to pain. It is specifically for women aged 18–48 who have migraine headaches 3–8 days per month.
Ribeirão Preto, São PauloAges 18–48 - NCT07514208Enrolling by invitation
Headache Sensitivity and Pain Testing Study
This study examines how sensitive the skin and tissues around the head are in people with migraines or tension headaches. Researchers will perform gentle touch and pressure tests to understand pain patterns, which may help improve headache treatment in the future.
Barcelona, BarcelonaAges 18 years+ - NCT07309874Recruiting
Dry needling for headache relief
This study tests if a specific type of dry needling (using a thin needle on tight neck muscles) can help reduce headaches. You may join if you've had headaches recently and have tender muscles at the base of your skull.
Lubbock, TexasAges 18–65 - NCT05415020Recruiting
Behavior program for chronic migraine
This trial tests a behavioral (talk/skills-based) program to help people with chronic migraine. It may help reduce migraine frequency or improve day-to-day coping.
Phoenix, ArizonaAges 18 years+ - NCT07268768Recruiting
Personality, thinking, and sensitivity in headache
This study looks at how personality, thinking skills, and heightened nerve sensitivity are connected in people with headache. It aims to better understand these relationships to improve care.
Messina, SicilyAges 18–60 - NCT03416114Recruiting
Registry for people with rare primary headache types
This trial is a registry that collects information about rare types of primary headaches in specialized Italian headache clinics. It may help researchers better understand these conditions and improve future care.
FlorenceAges Any age - NCT04151472RecruitingPhase 3
Idebenone to prevent episodic migraine attacks
This trial tests idebenone, a preventive medicine, to see if it can reduce how often migraine attacks happen. It mainly focuses on people with episodic migraine who have regular attacks and are not already using other migraine prevention treatments.
Hangzhou, ZhejiangAges 18–65 - NCT06041997Recruiting
Limiting smartphone use for headache relief
This trial tests whether reducing smartphone use can help treat primary headaches (migraines or tension headaches) in adults. If you get headaches that aren't caused by another medical condition, this study might be a good fit.
New Delhi, National Capital Territory of DelhiAges 18 years+ - NCT05902026Enrolling by invitation
Questionnaire study for jaw-related headache and pain impact
This study tests a biopsychosocial questionnaire (a survey about thoughts, daily life, and pain) for people with jaw-related headaches from temporomandibular disorder (TMD). It may help researchers better understand what influences headache severity and how to support treatment planning.
Gaziantep, Hasan Kalyoncu UniversityAges 18–60 - NCT07071506Recruiting
New tools to track migraine prevention
This study tests new ways to monitor how well preventive migraine treatments are working. It is for people with chronic migraine who may be starting or already using preventive medications.
Aarhus C, DenmarkAges 18–65 - NCT05414708Recruiting
Art therapy for veterans with PTSD symptoms
This study tests whether art therapy can improve emotional well-being in military members who have significant PTSD symptoms. You would answer questionnaires and likely take part in art-making sessions as part of the treatment being studied.
Bethesda, MarylandAges 18–64 - NCT05754190Recruiting
Smartphone study of mood and symptoms in people with pain
This study uses a smartphone app to track daily pain and mood changes over about 4 months. It’s meant to learn patterns that could help better understand how mood and pain affect each other.
Providence, Rhode IslandAges 18 years+ - NCT06608277RecruitingPhase 2
Ketamine and nerve block for headache or PTSD after brain injury
This study tests if ketamine infusions or a stellate ganglion block (a numbing injection near the neck) can help people with long-term headaches or PTSD after a traumatic brain injury. It compares these treatments alone and together.
Chicago, IllinoisAges 18 years+ - NCT07639944Recruiting
REN Device Study for Jaw Pain and Headaches
This study tests whether a treatment called REN can help reduce headaches and jaw pain caused by temporomandibular disorders (TMD). You would use the REN device at home on your smartphone or tablet over several months.
Ridgeland, MississippiAges 12 years+ - NCT07307508Recruiting
Scalp block for headache after aneurysm bleeding
This trial tests if a scalp nerve block can better manage severe headaches after a brain aneurysm rupture. It is for patients who had an aneurysm treated with coiling in the intensive care unit.
DohaAges 18 years+ - NCT07720765Recruiting
Using eye scans to study brain diseases
This trial uses a type of eye scan (OCT) to look at the retina in people with brain conditions like multiple sclerosis, Alzheimer's, Parkinson's, or migraines. It aims to see if these scans can help doctors learn more about the disease and monitor it over time.
Milan, MilanoAges 18 years+ - NCT06464367RecruitingEarly Phase 1
Psilocybin study for migraine and healthy volunteers
This study looks at how psilocybin affects the brain in people with migraines and in healthy volunteers. The goal is to understand why it may help with headache disorders.
West Haven, ConnecticutAges 21–70 - NCT07419607Recruiting
Group therapy with exercise for teens with migraine
This study tests a group therapy program for teens with migraine. The program combines physical activity, muscle relaxation, and education about migraines. It aims to help teens manage their headaches better.
Innsbruck, TyrolAges 13–17
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Headache Disorders trials by city
Studies with a site in or near these metro areas.
Headache Disorders trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for headache disorders?
- Yes. Clin2 currently lists 29 recruiting headache disorders studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a headache disorders trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a headache disorders trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.