Clinical trials
Health clinical trials
Below are recruiting health clinical trials, each written for real people, not researchers. We’re tracking 5,570 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04057638Recruiting
Facial and hand transplant study for severe face and hand loss
This trial looks at transplanting donor tissue to rebuild parts of the face and one or both hands/forearms after major damage or loss. It aims to see if this approach can restore function and appearance, while carefully managing safety and side effects like the need for long-term immune-suppressing medicines.
New York, New YorkAges 18–64 - NCT04063501Recruiting
Study of gut microbes during immunotherapy for lung cancer
This trial studies how gut bacteria (the microbiome) and the body’s immune signs change over time while you receive PD-1–based immunotherapy for advanced, unresectable non–small cell lung cancer. The goal is to learn which immune and microbial patterns might relate to how well treatment works and how patients respond.
New York, New YorkAges 18–100 - NCT04076735Recruiting
Compare fixing vs replacing certain leg bone fractures in seniors
This trial studies which operation works better for an acute distal femur (upper knee area) fracture in older adults: repairing/fixing it versus replacing the joint/bone. It may help find the safest approach and improve walking and recovery for people in this situation.
Toronto, OntarioAges 65 years+ - NCT04090034Recruiting
PRRT for advanced neuroendocrine tumors
This trial tests a treatment called PRRT, which delivers a radioactive medicine directly to tumor cells, for advanced neuroendocrine tumors. It may help those whose tumors are growing despite octreotide treatment, especially when scans show tumor uptake of specific tracers.
Dallas, TexasAges 18 years+ - NCT04092660Recruiting
Mouth guard study to reduce airway collapse in sleep apnea
This study tests whether using an anti-snoring mouth guard (a mandibular advancement appliance) can help keep your airway open during sleep if you have obstructive sleep apnea. If you’re referred for this kind of mouth guard, the trial will see if using it more regularly or in a specific way improves symptoms or breathing during sleep.
LondonAges 40–90 - NCT04099992Recruiting
Mindfulness program for people with chronic kidney disease
This trial tests whether a mindfulness-based program can help people living with moderate-to-advanced kidney disease. It may improve how you feel day-to-day and how you manage symptoms, while researchers track kidney-related health and safety.
Atlanta, GeorgiaAges 40–80 - NCT04110756Recruiting
Program to help teens change health behaviors
This study tests a program designed to help teens make healthier choices. It’s for teens who are 15–17 and are currently drinking alcohol, who come to specific UCSF pediatric check-up visits.
San Francisco, CaliforniaAges 15–17 - NCT04109235Recruiting
Exercise training for adults with type 2 diabetes
This trial tests whether a structured, higher-intensity interval exercise program is safe and helpful for adults with type 2 diabetes. You might benefit through improved fitness and diabetes-related health, but you must be medically cleared to exercise.
Aylmer, OntarioAges 18 years+ - NCT04134780Recruiting
Ultrasound tests to spot early breast cancer treatment response
This study uses special ultrasound imaging (and may use MRI results) to look for early signs of how locally advanced breast cancer responds to chemotherapy, with or without radiation. If the imaging changes early, it could help doctors adjust treatment sooner.
Houston, TexasAges 18 years+ - NCT04149977Recruiting
Blood flow restriction therapy for knee tendon injuries
This study tests whether blood flow restriction therapy can help healing and recovery after certain knee extensor injuries (like patella or quadriceps tendon rupture). You must be able to take part in the usual physical therapy plan, too.
New York, New YorkAges 18–65 - NCT04151342Recruiting
Study of Canadian adults with cancer rare DNA changes
This real-world study follows adults in Canada who have cancer that was tested and found to have rare molecular (DNA/protein) changes. It helps researchers understand how these rare findings show up and how care happens in everyday practice.
Calgary, AlbertaAges 18 years+ - NCT04153422RecruitingPhase 2
IVIG for small fiber nerve pain with specific antibody tests
This trial studies whether IVIG (an immune therapy made from donated antibodies) can reduce pain from autoimmune small fiber neuropathy. You may be a candidate if your tests show certain autoantibodies (TS-HDS, FGFR3, or Plexin-D1) and your symptom scores are high enough.
Glenview, IllinoisAges 18 years+ - NCT04159662Recruiting
Brain scans to study thinking in schizophrenia and depression
This study uses brain imaging to better understand how thinking works in people with schizophrenia or major depression. Your results may help researchers learn what brain patterns match different thinking and symptoms.
Ottawa, OntarioAges 18–60 - NCT04160533Recruiting
Registry for people diagnosed with high blood pressure
This registry collects information from people who have been diagnosed with high blood pressure. It may help researchers better understand who has it and how it’s managed in real life.
Moscow, Moscow OblastAges 18–99 - NCT04162444Recruiting
Aortic valve reconstruction study for children
This trial studies a surgery approach to help fix a narrowed or leaking aortic valve in children. It aims to see how well the reconstructed valve works and how it affects the child’s heart function over time.
MoscowAges 4 weeks–12 years - NCT04164940Recruiting
Tracking how hospital care affects alcohol risk in older adults
This study looks at how adults aged 21+ change over time after being admitted to the hospital for alcohol-related problems. It may help researchers understand which hospital approaches work best for reducing future alcohol-related harm—especially for people who have not had alcohol or drug use disorders before.
StavangerAges 21 years+ - NCT04170946RecruitingPhase 1
Talazoparib plus chest radiation after extensive small-cell lung cancer
This Phase 1 trial tests whether the medicine talazopib, given along with chest radiation, can better control extensive-stage small-cell lung cancer after initial chemotherapy. It is for people whose cancer has not worsened after finishing standard chemotherapy.
Toronto, OntarioAges 18 years+ - NCT04173416Recruiting
Support program for young adults in opioid recovery
This study tests a structured recovery support program for adults age 18–28 who have opioid use disorder. It may help by adding extra involvement and support while you receive common long-acting opioid treatment from a medical clinic.
Baltimore, MarylandAges 18–28 - NCT04179370Recruiting
Vitamin D and health in British African-Caribbean women
This study looks at vitamin D levels and how they relate to overall health in British African-Caribbean women. It may help researchers understand whether vitamin D support or lifestyle changes could benefit this group.
GuildfordAges 18 years+ - NCT04182607Recruiting
Looking at outcomes after kidney donation surgery
This review looks at results for kidney donors and recipients who had kidney transplant surgery done either by hand-assisted or robotic methods. It aims to understand how these surgical approaches affect donor and recipient outcomes.
Dallas, TexasAges 18 years+ - NCT04181138Recruiting
Study of childhood primary sclerosing cholangitis types
This study follows children and young adults with primary sclerosing cholangitis (PSC) to understand the condition and how it shows up on scans or biopsy. It may help doctors better recognize PSC and choose the best next steps for care.
Los Angeles, CaliforniaAges 2–25 - NCT04184479Recruiting
Test of a LEVAmethod program for adults with overweight
This study tests whether the LEVAmethod program helps adults with overweight or obesity when delivered in primary care. You may be asked to use digital tools and complete follow-up during the program.
GothenburgAges 18–75 - NCT04187729Recruiting
Precision Genomics Biobank for People Seen in Clinic
This study builds a large DNA and health information “biobank” from adults who visit Intermountain Health. It may help researchers understand how genes relate to health and disease by comparing “healthy” people with people who have medical conditions.
Murray, UtahAges 18 years+ - NCT04197297RecruitingPhase 2
Brain scan tests for biomarkers in people with brain metastases
This trial studies brain scan findings to see if specific imaging markers can help understand or predict outcomes in people with brain metastases. It may help researchers improve how brain metastases are evaluated before radiation treatment.
Toronto, OntarioAges 18 years+
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Common questions
- Are there clinical trials for health?
- Yes. Clin2 currently lists 5,570 recruiting health studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a health trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a health trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.