Clinical trials
Heart Transplantation clinical trials
Below are recruiting heart transplantation clinical trials, each written for real people, not researchers. We’re tracking 94 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07758894Recruiting
Breathing without a breathing tube during heart transplant surgery
This study tests whether heart transplant surgery can be done while the patient is awake and breathing on their own, instead of using a breathing tube. If successful, it may lead to faster recovery and fewer complications.
Guangzhou, GuangdongAges 18 years+ - NCT05270902Recruiting
Blood-filter treatment during heart transplant surgery
This study tests whether a blood-filter treatment used during a heart transplant can improve how the transplant goes for adults. You might be eligible if you’re having a heart transplant and meet the specific medication and procedure requirements.
Vienna, State of ViennaAges 18 years+ - NCT06428097RecruitingPhase 1
Thyroid hormone before heart transplant
This study tests whether giving a thyroid hormone supplement called levothyroxine before a heart transplant can help with recovery. It is for people already listed for a heart transplant who do not have thyroid problems.
San Francisco, CaliforniaAges 18 years+ - NCT05824364Recruiting
Exercise program after heart transplant
This trial studies an exercise program for people who have recently had a heart transplant. It may help improve recovery and physical function after transplant.
Milan, MilanAges 18 years+ - NCT05732779Recruiting
App-based check-ins to help teens take transplant medicines
This study tests a phone app that uses video check-ins (called directly observed therapy) to help adolescent heart-transplant patients take their immunosuppression medicines as prescribed. It may help reduce missed doses, which is important for protecting the transplanted heart.
Coral Gables, FloridaAges 10–21 - NCT04393181Recruiting
Study how donor heart function affects transplant outcomes
This study looks at how well donor hearts work and how that affects outcomes after heart transplantation. It may help transplant teams choose and use donor hearts more effectively.
Gothenburg, Västra Götaland CountyAges 18 years+ - NCT04066127Enrolling by invitation
Heart transplant study comparing two types of heart storage
This trial tests whether using a different method to store a donated heart before transplant improves outcomes. It compares “non-ischemic preservation” versus standard cold storage for people getting a new heart.
Lund, Skåne CountyAges 18 years+ - NCT03102125RecruitingPhase 4
Testing causes of heart transplant graft problems with scans
This study looks at why heart transplant “grafts” can start to malfunction again after transplant. If you qualify, you may undergo MRI and related heart testing to help researchers find ways to detect or understand graft dysfunction.
La Jolla, CaliforniaAges 18 years+ - NCT07079735RecruitingPhase 2/Phase 3
Preventing CMV after heart transplant
This trial compares two antiviral drugs, valganciclovir and letermovir, to see which works better at preventing CMV infection after a heart transplant. If you've had a heart transplant and haven't started preventive treatment yet, this study may be for you.
New York, New YorkAges 18–99 - NCT06478017RecruitingPhase 2
Belatacept for heart transplant patients
This study tests whether a drug called belatacept can safely help your body accept a new heart without rejecting it, and may reduce the need for other strong immune-suppressing medicines. If you are getting a heart transplant for the first time and have certain immune markers, this trial may be an option for you.
Los Angeles, CaliforniaAges 18–71 - NCT07531784Recruiting
Blood Test to Detect Heart Rejection After Transplant
This Swedish study tests whether a simple blood test can detect early signs that your body is rejecting a transplanted heart. The test looks for DNA fragments in your blood that may signal rejection before symptoms appear, potentially helping doctors catch problems sooner.
StockholmAges 18 years+ - NCT04477629RecruitingPhase 2
Belatacept for first-time heart transplant recipients
This trial studies whether belatacept, an anti-rejection medicine given by IV, can work for people receiving their first heart transplant. It aims to see if it prevents rejection safely for patients and whether it fits better than standard approaches for certain candidates.
New York, New YorkAges 18–75 - NCT06774365Recruiting
Heart imaging and blood tests for transplant rejection detection
This study uses advanced heart imaging and blood tests to detect a type of rejection that can happen after a heart transplant. It may help doctors diagnose antibody-mediated rejection earlier and more accurately.
Bari, BariAges 18 years+ - NCT05909150RecruitingPhase 2
Hypertonic saline to protect kidneys after a heart transplant
This trial tests whether a hypertonic salt fluid (a higher-salt saline solution) can help prevent sudden kidney injury after heart transplant surgery. If you’re recently hospitalized for a heart transplant, you may be eligible if specific kidney support needs and critical breathing/circulation devices aren’t already required.
São PauloAges 18 years+ - NCT06426173Recruiting
Strength training for people waiting for a heart transplant
This study tests whether resistance training (strength exercises) can help people waiting for a heart transplant. It is for patients who have been on the transplant list for less than a month and are stable enough to exercise safely.
São Paulo, São PauloAges 18–70 - NCT06773611Recruiting
Heart failure and transplant registry study
This study is creating a registry to track and learn from people with advanced heart failure or who have had a heart transplant. By joining, you help researchers better understand these conditions and improve care.
BolognaAges 18 years+ - NCT06784440Recruiting
Finding noninvasive markers of graft injury after heart transplant
This study looks for noninvasive markers (like blood or urine tests) that can show if a heart transplant is being injured. It aims to make monitoring safer and easier for children and adults with congenital heart disease who have had a transplant.
BolognaAges Up to 44 years - NCT06895070Recruiting
Heart transplant study using a special preservation machine
This trial tests a special machine that preserves donor hearts for longer periods before transplant. It may help people waiting for a heart transplant who need a heart from a donor that may be older or has some heart risks.
La Jolla, CaliforniaAges 18 years+ - NCT07291258Recruiting
Long-term health study of children born to transplant mothers
This study follows children born to mothers who had a solid organ transplant (like kidney, liver, or heart) to learn about their long-term health. It may help doctors understand how to better care for these families.
Groningen, Provincie GroningenAges Any age - NCT07360925Recruiting
Fat around heart arteries in transplant patients
This study looks at a type of fat around the heart's arteries in people who need a heart transplant. It may help doctors understand how fat affects heart disease.
PragueAges 30–90 - NCT07770659Recruiting
Using MRI to detect early heart transplant rejection
This study tests whether a heart MRI can detect early signs of organ rejection after a heart transplant. If successful, it could reduce the need for frequent biopsies.
Little Rock, ArkansasAges 6–25 - NCT04770012RecruitingPhase 3
Aspirin or clopidogrel after heart transplant
This study tests antiplatelet medicines (like aspirin or clopidogrel) in people who have had a heart transplant. The goal is to see if these medicines can safely help prevent blood-related complications after transplant.
Vancouver, British ColumbiaAges 18 years+ - NCT06774794Recruiting
Precision medicine for heart transplant patients
This trial uses precise, personalized approaches to manage heart transplant recipients. It involves taking a small heart muscle sample (a biopsy) to monitor for rejection or routine checks.
BolognaAges 18 years+ - NCT05729009Recruiting
Testing blood-vessel function changes after heart transplant
This study looks at how tiny blood vessels in the body work over time in people who have had a heart transplant. It aims to better understand changes in blood flow and how these may relate to health after transplant.
Rio de JaneiroAges 18–75
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Common questions
- Are there clinical trials for heart transplantation?
- Yes. Clin2 currently lists 94 recruiting heart transplantation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a heart transplantation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a heart transplantation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.