Clinical trials
Congenital Heart Disease clinical trials
Below are recruiting congenital heart disease clinical trials, each written for real people, not researchers. We’re tracking 183 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03626480Recruiting
Nutrition support before and after heart surgery for babies
This trial studies a nutrition plan given around the time of heart surgery for babies with congenital heart disease. It may help improve how babies grow and recover by supporting feeding before and after the operation.
Hangzhou, ZhejiangAges 1 day–1 year - NCT05081115Recruiting
Stress echo imaging for people with heart valve or muscle issues
This trial studies a stress echocardiogram (an ultrasound of the heart during stress) to better understand and improve future heart imaging. It may help by comparing how well the test works for different heart conditions.
BeneventoAges 18–75 - NCT05702203Recruiting
Music therapy for newborns with congenital heart disease
This trial tests whether creative music therapy can help newborn babies who have congenital heart disease (CHD) while they are in intensive care. It focuses on babies who are otherwise very young and in the NICU or PICU, regardless of CHD severity.
ZurichAges 1 minute–4 weeks - NCT02923440Recruiting
Donate DNA and help build a congenital heart study database
This study creates a DNA bank and a French database for babies and children with certain types of congenital heart defects, to better understand genetic causes. You’ll be asked to have a blood test and share consent, even though care can continue as usual at the study hospital.
MarseilleAges Any age - NCT01653223Recruiting
Simvastatin to protect the heart during heart surgery
This trial looks at whether simvastatin (a cholesterol medicine) can help protect the heart during cardiac surgery. You might be invited if you’re having surgery for certain, non-complex heart conditions, but not if you have some specific related health problems.
Guangzhou, GuangdongAges 18 years+ - NCT05838079Recruiting
Baby heart study for families affected by diabetes
This study looks at how diabetes during pregnancy affects children’s or babies’ heart health over time. It may help researchers understand risks early, especially for families with a diabetes history during pregnancy.
Copenhagen ØAges 1 day–99 years - NCT05996211Recruiting
Swiss Study on Brain Development in Children with Heart Defects
This study follows children with severe heart problems born recently to see how their brain development progresses. It helps doctors understand what support these children might need as they grow.
BernAges 1 week–1 month - NCT06089902Recruiting
European registry for anomalous aortic origin of coronary arteries
This is a European registry for people with an anomalous origin of a coronary artery from the aorta (AAOCA). It will track how the condition is treated—whether with surgery or monitoring—to learn what works best.
Padova, PDAges Any age - NCT06244940Recruiting
Genetic testing study for heart defects in pregnancy
This study tests a new way to find genetic causes of congenital heart disease (a heart problem found before birth) using samples from amniocentesis or chorionic villus sampling. It may help parents get a clearer diagnosis and plan for their baby's care.
San Diego, CaliforniaAges 18 years+ - NCT04217421RecruitingPhase 3
Allopurinol for newborns needing heart surgery with bypass
This trial tests whether the medicine allopurinol can protect the brain and heart in newborns with serious congenital heart disease who need heart surgery soon after birth. It may help reduce injury during and around surgery that uses a heart-lung machine (cardiopulmonary bypass).
GroningenAges Up to 1 month - NCT06371937Recruiting
Heart and blood vessel disease biobank study
This study creates a collection of skin cells (turned into stem cells in a lab) from people with various heart and blood vessel conditions. It aims to find new ways to understand and treat these diseases.
London, OntarioAges 18–80 - NCT07791069Enrolling by invitation
Study of a device to manage blood flow in the lungs for heart disease in young children
This study looks at how well a new device works to control blood flow to the lungs in children with heart problems. It reviews medical records of children who had this device placed in their lung arteries.
Le Plessis-RobinsonAges Up to 3 years - NCT07753681Recruiting
Chronic disease care in Zambia
This study helps improve care for people with long-term illnesses like diabetes or high blood pressure in Zambia. It aims to make sure you get regular check-ups and support.
Lusaka, Lusaka ProvinceAges Any age - NCT07716488Recruiting
Screening for high cholesterol in children with chronic conditions
This study screens children and teens with certain chronic conditions (like heart defects or inflammatory bowel disease) for early signs of high cholesterol or other lipid problems. The goal is to find and manage these risks sooner.
JenaAges 6–18 - NCT07700459Recruiting
Exercise prehabilitation for congenital heart surgery
This study tests whether a supervised exercise program before heart surgery can help adults with congenital heart disease recover better. You would join an exercise class 2–3 times a week for several weeks leading up to your operation.
LiverpoolAges 18 years+ - NCT07692958Recruiting
Thinking skills training for children with heart defects
This trial tests a program to help children born with heart problems improve their thinking and planning skills (called 'executive function'), which may be affected by their heart condition or surgery. It is for children aged 9 to 13 who had heart surgery before age 1 and show some difficulties with these skills.
Zurich, Canton of ZurichAges 9–13 - NCT07686341Recruiting
Precision oxygen monitor study for infants
This trial tests a new type of oxygen monitor (pulse oximeter) in babies under 1 year old. It helps doctors better track oxygen levels in critically ill infants to improve care.
Memphis, TennesseeAges birth–1 year - NCT06660524RecruitingPhase 4
Calcium-phosphorus therapy for heart valve disease
This trial tests a treatment to lower high calcium and phosphorus levels in your blood, which may slow down calcium buildup in heart valves. It may help people with kidney problems who have valve disease.
Beijing, Beijing MunicipalityAges 50 years+ - NCT05997680Recruiting
Yoga for attention in kids with heart disease
This study tests if a parent-child yoga program can help improve attention in children aged 4 to 6 with congenital heart disease who have attention difficulties. You and your child would attend yoga sessions together for 8 weeks.
Montreal, QuebecAges 4–6 - NCT07582861Recruiting
Support for Mothers Expecting Babies With Heart Disease
This study offers psychological support to pregnant mothers who have learned their baby has congenital heart disease (a heart condition present at birth). The research tests whether counseling and coping strategies provided before and after birth can help mothers manage stress and anxiety during this challenging time.
Phoenix, ArizonaAges 18 years+ - NCT07585175Recruiting
Moving from pediatric to adult heart disease care
This study helps doctors understand how to smoothly transition young people with heart problems they were born with from pediatric (children's) hospitals to adult care. It may help improve care coordination and outcomes as patients grow up.
Ottawa, OntarioAges 18 years+ - NCT07582848Recruiting
Breastfeeding Support for Babies with Heart Disease
This study helps mothers of babies born with heart defects learn to breastfeed directly, even when the baby needs heart surgery in the first month of life. Researchers want to see if direct breastfeeding improves health outcomes for both mother and baby during this critical time.
Phoenix, ArizonaAges 18 years+ - NCT06723704Recruiting
Long-term outlook in adults with congenital heart disease
This study looks at how adults with congenital heart disease (a heart problem you were born with) do over time. By reviewing medical records, doctors hope to learn what affects long-term health and help improve care for patients like you.
Rome, RMAges 18 years+ - NCT05698277Recruiting
Ultrasound to track baby heart function in heart disease
This study uses automated ultrasound measurements to track how a baby’s heart is working during pregnancy. It compares babies who have a specific congenital heart problem with babies without it, to understand what ultrasound can detect.
Sydney, New South WalesAges 18 years+
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Congenital Heart Disease trials by city
Studies with a site in or near these metro areas.
Congenital Heart Disease trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for congenital heart disease?
- Yes. Clin2 currently lists 183 recruiting congenital heart disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a congenital heart disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a congenital heart disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.