Clinical trials
HIV clinical trials
Below are recruiting hiv clinical trials, each written for real people, not researchers. We’re tracking 611 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05652088Recruiting
Study gut immune tissue in HIV cure efforts
This study looks at how immune tissue in the gut may be involved in curing HIV. You may be asked to have two colonoscopies while on an HIV “cure-related” treatment, so researchers can collect tissue samples to understand what’s happening in your body.
New York, New YorkAges 18–75 - NCT05660148Recruiting
HIV study on resentment, forgiveness, and quality of life
This study looks at how feelings like resentment and the ability to forgive relate to quality of life in people living with HIV. You may be asked to participate in questionnaires and/or follow-up that can be done by phone or video.
AmiensAges 18 years+ - NCT05663580Recruiting
Study of HIV treatment with long-acting injected medicines
This study follows adults with well-controlled HIV who are planning to switch to a long-acting HIV medicine given as injections. It may help researchers understand how this approach works for people already stable on current treatment.
MilanAges 18 years+ - NCT05669534RecruitingPhase 4
HIV prevention support for people starting PrEP
This study tests how to better support HIV prevention for people who inject drugs and are newly starting PrEP (medicine to prevent HIV). It focuses on people taking medication for opioid use disorder and who have mild thinking and memory problems, to help them stay safe and adhere to prevention.
New Haven, ConnecticutAges 18 years+ - NCT05678556Recruiting
Relationship education to help prevent HIV in gay and bisexual men
This trial tests a relationship education program to help reduce HIV risk by supporting safer sex choices. It is for people who are currently at higher risk and are HIV-negative.
Chicago, IllinoisAges 16–34 - NCT05774548Recruiting
Study of PrEP use and its cost in HIV prevention
This study looks at how taking PrEP (medicine to prevent HIV) affects HIV prevention and how much it costs in real life. You may be able to join if you are HIV-negative and are interested in starting, currently using, or have used PrEP before.
Bangkok, BangkapiAges 18 years+ - NCT05807867Recruiting
Support program to help women with HIV keep treatment working
This study tests a stigma-reducing support program to help women living with HIV and serious mental illness stay adherent to HIV treatment. It focuses on sustaining viral suppression by addressing stigma that can make care harder, and it involves family and community leaders as part of the approach.
GaboroneAges 18–65 - NCT05848570Recruiting
Digital program for reducing HIV risk in SGM youth
This trial tests a digital health program (available with limited in-person contact) to help SGM young people reduce their risk of HIV. You may be a good fit if you’re in the right age range and have had certain types of sex in the last 6 months.
Chicago, IllinoisAges 13–34 - NCT05849038RecruitingPhase 2
Treating inflammation to improve depression in HIV
This Phase 2 study looks at whether lowering inflammation can help improve depression symptoms in adults living with HIV. You may be able to join if your HIV is well controlled and you are currently experiencing major depression (or a certain type of bipolar depression).
Atlanta, GeorgiaAges 18–65 - NCT05858034Recruiting
Study of aging and frailty in people with HIV over 50
This study looks at what makes some people with HIV become “pre-frail” or frail as they get older. It uses questionnaires and other checks to understand challenges to healthy aging and may help improve future support and care.
Winston-Salem, North CarolinaAges 50 years+ - NCT05917210Recruiting
Peer support for TB and HIV treatment in Uganda
This trial tests a peer-led education and counseling program to help people with TB and HIV stick with their treatment. It may help improve understanding, motivation, and day-to-day adherence to medications.
KampalaAges 18 years+ - NCT05923333Recruiting
Breastfed infants of HIV-exposed mothers get a probiotic
This study gives a specific probiotic (from B. infantis) to babies born without HIV to see if it can improve the baby’s early immune health. It focuses on babies who are HIV-exposed because their mother has HIV and plans to exclusively breastfeed for the first 6 months.
Cape TownAges birth–50 years - NCT05929911Recruiting
Talk therapy for PTSD in people living with HIV
This trial tests whether trauma-focused psychodynamic talk therapy can reduce symptoms of post-traumatic stress disorder (PTSD) in people who also live with HIV. It may help by offering structured therapy alongside stable medication.
The Bronx, New YorkAges 18–65 - NCT05934305Recruiting
Help for shame and stigma in HIV and substance use
This study tests whether a program can reduce shame and stigma for people living with HIV who also have a substance use disorder. It may help you feel less judged and cope better, while supporting HIV care.
Miami, FloridaAges 18 years+ - NCT05943548Recruiting
Traditional healer support to help HIV reach low viral levels
This study tests whether support from traditional healers can help people with HIV get their viral load down to very low levels. You may be offered additional support and asked to attend clinic and nurse visits over 2 years.
MbararaAges 18 years+ - NCT05947890RecruitingPhase 2
Testing an immune-boosting TB vaccine in people with or without HIV
This Phase 2 study tests MTBVAC, a TB vaccine candidate, to see if it is safe and whether it helps the immune system. It may be a fit if you’re eligible for TB and HIV-related vaccine safety testing and can follow study visits and testing.
Johannesburg, GautengAges 12–55 - NCT05958017Recruiting
ReSET program to help stimulant use in HIV clinics
This study tests a care-support program called ReSET to improve adherence to treatment and reduce stimulant use for people living with HIV who are not currently in drug treatment. You may be offered support through HIV clinic care to help you stay on track, especially if you have access to a smartphone and stable housing.
Miami, FloridaAges 18–90 - NCT05965518Recruiting
High-intensity exercise for brain and blood-vessel health in HIV
This trial tests whether high-intensity exercise can improve blood-vessel health and brain function in adults with HIV who are not very active and have thinking/memory problems. If you qualify, you’ll be asked to safely complete exercise and other study assessments.
Birmingham, AlabamaAges 50 years+ - NCT05996016Recruiting
Gut and vaginal bacteria in HIV-positive women
This study looks at the types of bacteria living in the gut and vagina of women with HIV, including pregnant women. It aims to understand how these bacteria might affect health.
Beijing, Beijing MunicipalityAges 14 years+ - NCT06001814Recruiting
Mindfulness program for heart health in older adults with HIV
This study tests whether a mindfulness and behavior change program can help older adults with HIV improve their heart health. It combines phone-based coaching and text messages to reduce stress and manage heart risk factors like high blood pressure and diabetes.
Boston, MassachusettsAges 50 years+ - NCT06013579Recruiting
Exercise study for older adults with HIV
This study tests whether high-intensity exercise can help improve thinking and memory, and build lasting exercise habits, in older adults living with HIV who feel tired and are not very active.
Birmingham, AlabamaAges 50–80 - NCT06022549Recruiting
Mobile health for HIV patients with metabolic and bone issues
This trial tests a mobile health program designed to help people with HIV manage metabolic syndrome and bone loss. It aims to find if text messages and health tips can improve your health.
TaipeiAges 30 years+ - NCT06034938RecruitingPhase 2
Switching HIV Meds for People With M184V Mutation
This study tests switching your current HIV medicines to a once-daily pill combining doravirine, tenofovir, and lamivudine, specifically for people whose virus has a past M184V mutation but is now well controlled.
CaenAges 18 years+ - NCT06055868Recruiting
HIV, oral cancer, and health equity study
This study looks at the experiences of people living with HIV who also have oral or throat cancer. The goal is to understand health disparities and improve care.
San Francisco, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for hiv?
- Yes. Clin2 currently lists 611 recruiting hiv studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a hiv trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a hiv trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.