Clinical trials
HIV clinical trials
Below are recruiting hiv clinical trials, each written for real people, not researchers. We’re tracking 583 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05580666RecruitingPhase 3
Lower death risk by adding azithromycin to HIV treatment
This Phase 3 study tests whether adding azithromycin helps people with advanced HIV disease live longer. You would start (or restart or adjust) HIV treatment within 4 weeks and may also receive azithromycin or a comparison approach to see if outcomes improve.
AbidjanAges 18 years+ - NCT06541028Recruiting
Quick-start HIV treatment study for people who inject drugs
This study tests a rapid-start antiretroviral therapy (ART) approach for people who inject drugs and have HIV. The goal is to see if starting HIV medicine quickly helps reduce stigma and improve health outcomes.
KajangAges 18 years+ - NCT06517693RecruitingPhase 1
HIV antibody safety study for newborns at risk
This study tests whether giving a combination of two lab-made antibodies (PGT121.414.LS and VRC07-523LS) to newborns exposed to HIV during pregnancy is safe and how the body processes them. It may help protect infants from getting HIV after birth.
Los Angeles, CaliforniaAges Up to 3 days - NCT06513819RecruitingPhase 1
HIV and Alcohol Study for People on Multiple Medications
This study looks at how alcohol use affects people with HIV who take multiple medications, including certain brain or nerve drugs. It aims to find safer ways to manage their health.
West Haven, ConnecticutAges 50 years+ - NCT06497465RecruitingPhase 3
Two-drug HIV treatment for people with TB
This trial tests a two-drug HIV treatment for people who are new to HIV therapy and also have tuberculosis. It compares the two-drug combination to the standard three-drug regimen, with the goal of making treatment simpler while still being effective.
Manaus, AmazonasAges 15–99 - NCT06506188Recruiting
Improving HIV prevention for breastfeeding women in Malawi
This study looks at how to make it easier for women in Malawi to stay on PrEP after giving birth while breastfeeding. Researchers will check medical records and ask some women to do a short survey and a finger stick blood test.
LilongweAges 15–99 - NCT06477588Recruiting
HIV services and job help for justice-involved Black men
This study helps Black men who have sex with men or other key populations who have been involved with the justice system get HIV services and job support. It aims to connect you to care and employment help, especially if you aren't already receiving HIV or PrEP care.
Chicago, IllinoisAges 18 years+ - NCT06488846Enrolling by invitation
Giving HIV injections at home with a helper
This study tests whether having a trained friend or family member give you your HIV injections at home is safe and works as well as getting them at a clinic. You may qualify if you are already on the injectable HIV medication cabotegravir/rilpivirine (Cabenuva) and have a support person willing to help.
San Francisco, CaliforniaAges 18 years+ - NCT06493357Recruiting
Improving HIV testing and care for mothers and babies in Malawi
This study is testing a new way to find and treat HIV in pregnant women and new mothers in Malawi. It may help prevent passing HIV from mother to baby.
Lilongwe, Central RegionAges 16 years+ - NCT05570812RecruitingPhase 2
Pregnenolone to improve depressed mood in people with HIV
This Phase 2 trial tests a brain-acting steroid called pregnenolone to help reduce depressed mood. It studies whether it can improve mood in adults with HIV who are already on HIV treatment and still have depression symptoms.
Boston, MassachusettsAges 18–85 - NCT06428643Recruiting
Chlamydia prevention program for young Black adults in New Orleans
This study tests a program to help reduce chlamydia infections in young Black or African American people in New Orleans. It involves testing for chlamydia and then providing treatment or prevention support.
New Orleans, LouisianaAges 15–26 - NCT06406049Recruiting
Finishing HIV prevention study
This study is for cis-gender men who are HIV-negative and at risk for HIV. It tests a program to help you start and stay on PrEP (medication to prevent HIV).
Miami, FloridaAges 18–54 - NCT06408142Recruiting
HIV testing and connection to care in South African ERs
This study tests a program that offers HIV testing and connects people to prevention or care right in the Emergency Department. It aims to make it easier for anyone visiting the ER to get the HIV services they need.
Cape Town, Western CapeAges 12 years+ - NCT06395129Recruiting
Better syringes for people who inject drugs
This study provides safer, low-dead-space syringes to people who inject drugs to help reduce the spread of infections like HIV and hepatitis C. It is designed for people in low- and middle-income countries who use needle exchange programs.
YerevanAges 18 years+ - NCT06370481Recruiting
HIV and addiction training program for Alabama clinics
This study tests a program to help people living with HIV in Alabama who also struggle with opioid or stimulant use. It takes place at your HIV clinic and checks whether a new approach to addiction care can improve your health.
Birmingham, AlabamaAges 18 years+ - NCT06001814Recruiting
Mindfulness program for heart health in older adults with HIV
This study tests whether a mindfulness and behavior change program can help older adults with HIV improve their heart health. It combines phone-based coaching and text messages to reduce stress and manage heart risk factors like high blood pressure and diabetes.
Boston, MassachusettsAges 50 years+ - NCT06350682Enrolling by invitation
HIV prevention app study for young men
This study tests a smartphone program to help young men who have sex with men stay healthy and prevent HIV. It's designed for people already getting care at certain clinics.
Abuja, NigeriaAges 15–24 - NCT06337032RecruitingPhase 4
Continued access to HIV treatment for children and teens
This trial provides continued access to Biktarvy (B/F/TAF) for children and adolescents who completed a previous Gilead HIV study. It ensures they can keep taking the medication without interruption.
Buenos AiresAges 1 month+ - NCT06334341Enrolling by invitation
Study to improve PrEP use in primary care
This trial tests ways to help primary care providers and their patients start using PrEP, a daily pill that prevents HIV. It may be right for you if you are interested in HIV prevention.
Detroit, MichiganAges 18 years+ - NCT06307977Recruiting
Couples counseling to reduce drug use and HIV risk
This study tests a couple-focused counseling approach to help male couples reduce drug use and lower the risk of HIV. You and your partner would join sessions together to talk about safer choices and support each other.
Detroit, MichiganAges 18–55 - NCT05303337Recruiting
Study of gut and HIV changes after switching to long-acting shots
This trial compares how HIV “reservoirs,” inflammation, and the gut microbiome change when people switch from daily HIV pills to long-acting injectable treatment. It may help you and your team understand what to expect with the switch and how your body responds.
MarseilleAges 18 years+ - NCT05078957Recruiting
Study gut microbiome in older adults with well-controlled HIV
This trial studies how the bacteria in your gut (“microbiome”) relate to frailty (weakness/low physical resilience) in people with HIV who are stably doing well on treatment. It may help researchers understand why some people become frail and how the gut may play a role.
MarseilleAges 55 years+ - NCT06269081Recruiting
Testing two programs to help older rural adults with HIV
This study tests two different programs to see if they can improve health and quality of life for older adults living with HIV in rural areas. You may join if you live in certain states and have a phone.
Milwaukee, WisconsinAges 50 years+ - NCT06266416Recruiting
Black caregivers & girls empowerment study
This study tests a program called IMARA to support black male caregivers and the girls they care for. It aims to improve family relationships and reduce risky behaviors in girls.
Chicago, IllinoisAges 13 years+
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Common questions
- Are there clinical trials for hiv?
- Yes. Clin2 currently lists 583 recruiting hiv studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a hiv trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a hiv trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.