Clinical trials
Humans clinical trials
Below are recruiting humans clinical trials, each written for real people, not researchers. We’re tracking 1,251 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07684196RecruitingPhase 1
First test of ENC0653 ointment in healthy adults
This study tests a new ointment called ENC0653 in healthy adults to see if it is safe and how it works in the body. It is the first time this ointment is being tested in people, so if you are healthy and your skin is clear, you may be able to help.
Shanghai, Xuhui DistrictAges 18–55 - NCT07684898RecruitingPhase 3
Long-acting factor VIII for severe hemophilia A
This trial tests a new long-acting factor VIII treatment (FRSW107) for people with severe hemophilia A. It aims to prevent bleeding episodes with fewer injections, and you must have already used factor VIII treatments many times before.
Tianjin, Tianjin MunicipalityAges 12–65 - NCT07384715RecruitingPhase 1
GEN3018 for AML or high-risk MDS
This trial tests a new drug called GEN3018 for people with acute myeloid leukemia (AML) or higher-risk myelodysplastic syndrome (MDS) that has come back or not responded to standard treatments. It aims to see if the drug is safe and effective.
AarhusAges 18 years+ - NCT07337525RecruitingPhase 1
First study of PLT012 in advanced solid tumors
This trial tests a new drug called PLT012 for people with advanced solid tumors. It is the first study in humans, so doctors will see if the drug is safe and how the body handles it.
Los Angeles, CaliforniaAges 18 years+ - NCT07226427RecruitingPhase 1
Study of MEN2501 for platinum-resistant ovarian cancer
This trial tests a new drug called MEN2501 for people with ovarian cancer that no longer responds to platinum-based chemotherapy. The goal is to see if it is safe and if it can help shrink tumors.
Springdale, ArkansasAges 18 years+ - NCT06708780RecruitingPhase 1
Treg cell therapy for type 1 diabetes
This trial tests whether giving your own regulatory T cells (a type of immune cell) back to you can help slow or stop the immune attack on your pancreas in type 1 diabetes. It is for people aged 8 to 65 who still make some insulin.
Nanjing, JiangsuAges 8–65 - NCT06716281RecruitingPhase 3
Stem cell injection for knee osteoarthritis
This study tests a new stem cell treatment for knee osteoarthritis. It aims to see if injecting these cells into the knee can reduce pain and improve function compared to other treatments.
ShanghaiAges 40–80 - NCT06727253Recruiting
Glycan supplement study for Crohn's disease after surgery
This trial tests whether a glycan supplement can prevent Crohn's disease from coming back after surgery to remove the diseased part of the small and large intestine. It may help people who have had this specific surgery and are not taking certain other treatments.
Lisbon, Lisbon DistrictAges 18–75 - NCT06727721RecruitingPhase 2
Stem cell therapy for hard-to-treat type 2 diabetes
This trial tests a new stem cell treatment for people with type 2 diabetes that is difficult to control with standard medications. The treatment uses a special kind of stem cell to try to improve blood sugar levels.
ShanghaiAges 18–70 - NCT06746688RecruitingPhase 1
Safety study of ES2B-C001 for HER2-positive metastatic breast cancer
This trial tests a new drug called ES2B-C001, with or without an adjuvant, to see if it is safe for people with HER2-positive breast cancer that has spread and has not responded to previous treatments.
GrazAges 18 years+ - NCT06747390RecruitingPhase 1
Lidocaine injection before throat cancer surgery
This early-phase trial tests whether injecting lidocaine (a numbing medicine) into the tumor before surgery can help with pain or other outcomes in people with oropharyngeal cancer. It's for patients who are already scheduled for a scope procedure and surgery at the University of Pennsylvania.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06749366Recruiting
Finding Genes Linked to Cartilage Tumors and Blood Vessel Issues
This study uses genetic testing to find genes that cause certain types of cartilage tumors and blood vessel problems. If you or your child has one of these conditions, joining could help doctors understand what causes them and find better treatments.
Bethesda, MarylandAges 2–100 - NCT06751199Recruiting
Stem cells combined with islet transplant for diabetes
This trial tests if umbilical cord stem cells can improve the success of islet cell transplants for people with diabetes whose own pancreas no longer makes enough insulin. It aims to help patients achieve better blood sugar control and reduce dangerous low blood sugar episodes.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT06760819RecruitingPhase 2
Sevacertinib for solid tumors with HER2 mutations
This study tests an oral tablet called sevacertinib in people with solid tumors (not lung cancer) that have a HER2 mutation. It aims to see how well the drug works and how safe it is for people who have tried other treatments or have no good options left.
Birmingham, AlabamaAges 18 years+ - NCT06772493Recruiting
First test of a new ICE ultrasound tool in people
This study is testing a new type of ICE ultrasound tool during heart procedures. The goal is to see how well it works in real people.
Jonesboro, ArkansasAges 18 years+ - NCT06775457Recruiting
Genetic study of HERVs in children with new inflammation
This study looks at certain genes (called HERVs) in children with new inflammatory conditions like Kawasaki disease, COVID-19, or other infections. It aims to learn more about how these genes might be involved in the body's response to illness.
Carpi, ModenaAges Up to 18 years - NCT06776341Recruiting
Study of GEMIN-5 genetic disorder
This study follows people with a confirmed GEMIN-5 genetic condition to learn more about how it affects their health and development over time. It aims to improve understanding and future care.
Pittsburgh, PennsylvaniaAges Any age - NCT06778239Recruiting
Childhood high blood pressure natural history study
This study follows children and young adults who have high blood pressure that started in childhood. It aims to understand why some kids develop high blood pressure without a clear cause, by looking at their genes, family history, and health over time. Participants will provide samples and medical information to help researchers learn more.
Bethesda, MarylandAges 2–99 - NCT06781333RecruitingPhase 2
Stem cells for behavior problems in Alzheimer's
This trial tests whether a single infusion of human mesenchymal stem cells (hMSC) can improve difficult behaviors like agitation, anxiety, or hallucinations in people with Alzheimer's disease. It's designed for those who have been taking antipsychotic medication for at least 4 weeks and have a study partner to help track behavior changes.
Miami, FloridaAges 55–90 - NCT06783569RecruitingPhase 1
First-in-human study for advanced solid tumors
This trial tests a new experimental drug for people with advanced solid tumors that have not responded to standard treatments. It aims to find a safe dose and see if the drug can shrink tumors.
Harbin, Heiljiang ProvinceAges 18 years+ - NCT06787963Recruiting
Breast milk proteins study for healthy moms
This study looks at the small proteins and peptides in breast milk and how they change over time. It aims to understand the health benefits of these components for breastfed babies, particularly when moms exclusively breastfeed for 4 months.
Córdoba, CórdobaAges birth–4 months - NCT06789172RecruitingPhase 1
New drug OKN4395 with or without pembrolizumab for solid tumors
This trial tests a new oral drug called OKN4395, which targets a COX2-related immune pathway, alone or with the immunotherapy pembrolizumab, in people with advanced solid tumors. It may be an option if you have certain types of cancer that have stopped responding to other treatments.
Beverly Hills, CaliforniaAges 18 years+ - NCT06789861RecruitingPhase 1
First test of TT5 in healthy volunteers and surgical patients
This is a first-in-human study testing a new medicine (TT5) in healthy people and patients recovering from surgery. It checks how the body handles the drug and whether it is safe to use for pain.
Adelaide, South AustraliaAges 18–55 - NCT06797999RecruitingPhase 1/Phase 2
Study of ADCE-D01 for soft tissue sarcoma
This trial tests a new drug called ADCE-D01 for people with soft tissue sarcoma that has spread or cannot be removed by surgery. The goal is to see if it is safe and effective.
Aurora, ColoradoAges 18 years+
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Common questions
- Are there clinical trials for humans?
- Yes. Clin2 currently lists 1,251 recruiting humans studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a humans trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a humans trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.