Clinical trials
Humans clinical trials
Below are recruiting humans clinical trials, each written for real people, not researchers. We’re tracking 1,228 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05216432RecruitingPhase 1
RLY-2608 for PIK3CA-mutant advanced solid tumors and breast cancer
This early study (Phase 1) tests RLY-2608, a targeted cancer drug for tumors with a PIK3CA mutation. It studies the drug alone and combined with hormone therapy (and sometimes CDK4/6 or CDK4 medicines) to see safety, dose, and whether it can shrink tumors.
Tucson, ArizonaAges 18 years+ - NCT06348134RecruitingPhase 2
Anti-HER2 Therapy Before and After Surgery for HER2-Positive Breast Cancer
This trial tests a targeted therapy (anti-HER2) given before and after surgery for Nigerian women with HER2-positive breast cancer. It aims to see if this treatment helps shrink tumors and improve outcomes.
Ikeja, LagosAges 18 years+ - NCT06354088RecruitingPhase 1
Study of alpelisib for insulin resistance
This study tests a single dose of a drug called alpelisib (a PI3K inhibitor) to see how it affects insulin and blood sugar in people who are either insulin sensitive or insulin resistant. The goal is to understand why some people become resistant to insulin, which may help find new treatments for diabetes and related conditions.
New York, New YorkAges 18–70 - NCT06337318RecruitingPhase 3
Comparing two drugs for low-tumor burden follicular lymphoma
This trial compares a standard drug called rituximab to a newer medicine called mosunetuzumab for people with a slow-growing type of lymphoma that is not causing many symptoms. The goal is to see if mosunetuzumab works better and has fewer side effects.
Birmingham, AlabamaAges 18 years+ - NCT05606133Recruiting
Test HPV DNA from blood to track cervical cancer risk
This study looks at a blood test that measures HPV DNA to help screen and monitor people with HPV-related cervical problems. If you have confirmed high-grade cervical changes or cervical cancer, the test may help doctors follow how your condition changes over time.
New York, New YorkAges 18 years+ - NCT06310551RecruitingPhase 1
Long-acting HIV prevention study for healthy adults
This study tests a new long-acting medicine that may help prevent HIV. It is given as an injection, and the study checks how safe it is and how it works in healthy volunteers.
Lenexa, KansasAges 18–55 - NCT06297590RecruitingPhase 1
First human study of a new Alzheimer's drug
This study tests an experimental drug (LY3954068) for people with early Alzheimer's disease. It aims to see if the drug is safe and may slow memory loss. You'll need a PET scan to measure tau protein in the brain and have a study partner who can help attend appointments.
Maitland, FloridaAges 50–85 - NCT06296823Recruiting
Daily rhythms in healthy young adults
This study looks at how your body's daily rhythms (your internal clock) work by measuring natural chemicals in your body. It's for healthy people aged 17-35 who live at or above Denver's altitude.
Boulder, ColoradoAges 17–35 - NCT06292728Recruiting
Study of the ENDOPLY System for Weight Loss
This trial tests a new device called the ENDOPLY system, which is placed inside the stomach through a tube in the mouth to help with weight loss. It is for people who have struggled with dieting and have a BMI between 30 and 40.
BrnoAges 18–60 - NCT06285409Recruiting
Uterus contraction medicine study during planned C-sections
This study looks at how well different doses of a contraction medicine work after an initial dose in women having a planned C-section. It may help find the best way to prevent bleeding after birth.
Toronto, OntarioAges 18–45 - NCT06241898RecruitingPhase 1
First study of a new drug for advanced solid tumors
This study tests a new drug (BB-1709) for people with advanced solid tumors that haven't responded to standard treatments. The goal is to see if it's safe and how well it works.
Beijing, Beijing MunicipalityAges 18–78 - NCT06269653Recruiting
Protein turnover study across the lifespan
This study measures how the body makes and breaks down proteins throughout life. You drink a small amount of special water (deuterium oxide) and give a few blood, urine, and muscle samples to track protein changes.
Baltimore, MarylandAges 20–120 - NCT06266689Recruiting
Dietary data return for infants
This study asks parents to collect and mail in stool samples from their infant over the next two years. Researchers want to learn more about how diet affects baby health.
Durham, North CarolinaAges Up to 1 year - NCT06272110Recruiting
Improving language access for patients and families
This trial looks at how to improve language services for people who prefer a language other than English. It involves surveys and interviews with patients, caregivers, community members, and hospital staff.
New York, New YorkAges 18 years+ - NCT06254846Recruiting
Urine test for HPV cervical cancer screening
This study tests if a urine sample can replace a cervical swab for HPV testing during cervical cancer screening. If it works, it could make screening easier and less uncomfortable.
Saint-EtienneAges 30–65 - NCT06254911RecruitingPhase 2
Immunotherapy before surgery for HPV-related throat cancer
This trial tests whether giving the drug atezolizumab before surgery can help shrink HPV-related throat cancer and improve outcomes. Atezolizumab helps your immune system fight cancer cells.
Atlanta, GeorgiaAges 18 years+ - NCT06263543RecruitingPhase 2
Sequencing antibody-drug conjugates in ER+, HER2-low breast cancer
This trial tests different sequences of antibody-drug conjugates (a type of targeted chemotherapy) for people with ER-positive, HER2-low or ultra-low metastatic breast cancer that has stopped responding to hormone therapy and has progressed on Enhertu. You must have had 1–4 prior chemotherapies for metastatic disease.
Miami, FloridaAges 18 years+ - NCT06265688RecruitingPhase 1
First study of CX-2051 for advanced solid tumors
This study is testing a new drug called CX-2051 for people with advanced solid tumors that have not responded to standard treatments. The drug is a type of targeted therapy that delivers chemotherapy directly to cancer cells, and the goal is to see if it is safe and effective.
Denver, ColoradoAges 18 years+ - NCT06253130RecruitingPhase 1/Phase 2
Study of IMP1734 for Advanced Solid Tumors with HRR Mutations
This trial tests a new drug called IMP1734 for people with advanced breast, ovarian, or prostate cancer that has a specific genetic change called an HRR mutation. The drug targets a protein called PARP1 to try to stop cancer cells from repairing themselves.
Tucson, ArizonaAges 18–89 - NCT06252220RecruitingPhase 1
Testing a new drug for obesity in healthy adults
This trial tests a new medication called DA-1726 for people with obesity but no other major health problems. It aims to see if the drug is safe and how it works in the body. You may qualify if your body mass index (BMI) is between 30 and 45 and your weight has been stable for 3 months.
Miami, FloridaAges 18–65 - NCT06233942RecruitingPhase 1
Testing a new drug for advanced solid tumors
This early-phase trial tests a new drug called BG-C9074, either alone or with other cancer treatments, for people with certain advanced solid tumors that have not responded to standard therapy. The goal is to see if it is safe and effective.
Los Angeles, CaliforniaAges 18 years+ - NCT06246942Recruiting
Understanding brain connections in healthy adults
This study uses brain scans to learn how different parts of the brain connect and communicate in healthy people. If you join, you will help researchers better understand normal brain function.
Boston, MassachusettsAges 18–64 - NCT06251544RecruitingPhase 1
CAR T cells for HER2-positive metastatic breast cancer
This trial tests a new type of immune cell therapy (CAR T cells) that targets two markers on cancer cells: TRAIL-R2 and HER2. It is for people with advanced or recurrent HER2-positive breast cancer that has not been stopped by standard treatment.
Houston, TexasAges 18–80 - NCT06208085Recruiting
Avocado, breast milk nutrients, and baby brain development
This study looks at how eating avocados affects the nutrients in your breast milk and your baby's brain development. If you are healthy, breastfeeding exclusively, and plan to continue for 6 months, you may be able to join.
Kannapolis, North CarolinaAges 18–40
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Common questions
- Are there clinical trials for humans?
- Yes. Clin2 currently lists 1,228 recruiting humans studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a humans trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a humans trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.