Clinical trials
Hypersensitivity clinical trials
Below are recruiting hypersensitivity clinical trials, each written for real people, not researchers. We’re tracking 58 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05420935Recruiting
Study of antibodies after operating-room allergic reactions
This study looks at different kinds of allergy-related antibodies in people who had an allergic reaction during surgery. The goal is to better understand what immune signals are involved so future allergy prevention and care can improve.
Paris, ParisAges 18–70 - NCT06755281Recruiting
Testing to safely remove penicillin allergy labels
This study tests if people with a low-risk penicillin allergy can safely have the allergy label removed through a simple risk assessment and testing, without needing a full drug challenge. It aims to help more people get the right antibiotics when needed.
Heidelberg, Baden-WurttembergAges 18 years+ - NCT06811389Recruiting
Peer support program for hypersensitivity pneumonitis
This study tests a program that pairs you with a peer coach (a trained person with lived experience) to help you manage hypersensitivity pneumonitis through education, support, and gentle physical activity. It's designed to see if this kind of support helps people feel better and stay active.
New York, New YorkAges 18–100 - NCT07041424Enrolling by invitation
Bonding methods for filling cavities to reduce tooth sensitivity
This trial tests two ways of bonding a tooth-colored filling to see which reduces tooth sensitivity after the procedure. It may help if you have a moderate cavity on a back tooth that causes brief pain or sensitivity.
Islamabad, FederalAges 18 years+ - NCT04654923Recruiting
Survey of allergic reactions around anesthesia
This study collects information about people who had an allergic-type reaction around surgery or anesthesia. It aims to understand how often these reactions happen and to improve future care. You may be able to join if your reaction fits the time window and you agree to use your records.
StrasbourgAges 7 years+ - NCT05259826Recruiting
Testing a gut-based IgE blood test for food allergy
This study looks at whether a specific immune signal (IgE) found in the gut lining can help diagnose food allergy or food-related hypersensitivity. You may join if you have symptoms that suggest a food allergy, or (if you’re healthy) if you need endoscopy for other reasons.
ErlangenAges 18 years+ - NCT05549635Recruiting
Database and blood sample registry for hypersensitivity pneumonitis
This trial is building a patient database and collection of samples from people with hypersensitivity pneumonitis (HP), a lung condition caused by breathing in an allergy-like trigger. Your information and samples may help researchers learn how HP is diagnosed and tracked over time.
Hellerup, CopenhagenAges 18 years+ - NCT06627790RecruitingPhase 3
Herbal mouthwash for tooth sensitivity
This study tests a herbal mouthwash containing potassium nitrate against a potassium oxalate mouthwash to see which better reduces tooth sensitivity. If you have sensitive teeth, you may be eligible to try a new rinse that could help reduce pain.
Pune, MaharashtraAges 18–60 - NCT06633627Recruiting
Brain response study for tooth sensitivity
This study looks at how your brain responds to tooth sensitivity. Researchers will test a simple air puff on your teeth and measure brain activity to better understand nerve signals from sensitive teeth.
SheffieldAges 18 years+ - NCT06685016Recruiting
Study of dental health after IPR with clear aligners
This study looks at how the teeth and gums are doing after a common orthodontic step called IPR (a slight smoothing between teeth) in people wearing clear aligners. It will help understand if this procedure keeps your mouth healthy.
NaplesAges 17–100 - NCT07281651Recruiting
Understanding pain sensitivity in knee pain and fibromyalgia
This study looks at how the brain and nerves process pain in people with knee pain or fibromyalgia. It compares them to pain-free people to understand differences in muscle signals.
Derby, DerbyshireAges 40 years+ - NCT07286344Recruiting
Fluoride varnish for tooth sensitivity
This trial tests whether a special fluoride varnish can reduce dentin hypersensitivity (tooth sensitivity). If you have sensitive teeth, this study may help find a better treatment.
Concepción, BiobioAges 18–40 - NCT07337109Recruiting
Study on tooth sensitivity and quality of life
This study looks at how tooth sensitivity affects your daily life and what treatments people use. It is for people who have recently started having sensitive teeth and have tried products for it.
Las Vegas, NevadaAges 18 years+ - NCT07605806RecruitingPhase 1/Phase 2
Understanding Drug Reactions to Vancomycin
This research study tests a new antibiotic called vancomycin to understand how the body reacts to it and identify early warning signs. If you qualify, you'll help researchers learn more about sudden allergic-like reactions that aren't traditional allergies.
Baltimore, MarylandAges 18 years+ - NCT06837779Enrolling by invitation
Study for treating sensitive teeth with fluoride and mineral boosters
This trial tests if applying fluoride using a mild electric current (iontophoresis) with other minerals can reduce pain in sensitive tooth roots. It may be an option if you have at least four sensitive back teeth.
Cairo, Cairo GovernorateAges 35–60 - NCT07622043Recruiting
Testing two varnishes to reduce tooth sensitivity
This study compares two special varnish coatings applied to teeth to see which works better at reducing tooth sensitivity and pain. If you have teeth that hurt when exposed to cold or touch, this trial might help you find relief.
SchaanAges 18–65 - NCT07595367RecruitingPhase 2
BBD-1 immune therapy for IgA vasculitis
This trial tests a new drug called BBD-1 that may help treat IgA vasculitis, a condition where your immune system attacks small blood vessels, causing a purple rash and organ damage. The study measures how well BBD-1 reduces symptoms and side effects.
Baltimore, MarylandAges Any age - NCT07038746RecruitingPhase 1
Inhaled epinephrine for severe allergic reactions during tests or treatment
This trial tests if inhaled epinephrine can safely treat moderate to severe allergic reactions (grade 2 or higher) that can happen during allergy skin tests, oral food or drug challenges, or allergy shots. It is for people who have had such reactions in the past or are at risk and are planning to undergo one of these procedures.
Richmond, British ColumbiaAges 12 years+ - NCT07664592RecruitingPhase 3
Comparing toothpastes for sensitive teeth
This trial tests whether a new toothpaste technology can block the tiny tubules in dentin that cause tooth sensitivity. It lasts 2 weeks and will help find better ways to treat sensitive teeth.
Porto Alegre, Rio Grande do SulAges 18–70 - NCT06746883Recruiting
Safety study of an antibiotic for ABC infection
This study checks how safe sulbactam-durlobactam (a combination antibiotic) is in adults with a serious infection caused by ABC bacteria, especially looking for allergic reactions. If you are already getting this antibiotic as part of your care, you may be able to join.
Sacramento, CaliforniaAges 18 years+ - NCT07727044Recruiting
Color and sensitivity of MIH teeth in children
This study looks at whether the color of spotted first permanent molars (caused by MIH) is linked to tooth sensitivity. It compares children with MIH to children with healthy teeth to understand the connection between color and pain.
Basel, Canton of Basel-CityAges 5–8 - NCT03800017Recruiting
Muscle strength and exercise function in lung scarring
This study looks at how well skeletal (muscle) function supports exercise in people with interstitial lung diseases (including idiopathic pulmonary fibrosis). It may help better understand fitness and breathing limits, which can guide rehabilitation choices and future care.
Vancouver, British ColumbiaAges 40–80 - NCT04330118Recruiting
Study immune cells in DRESS and drug rash reactions
This trial studies how certain immune cells (eosinophils) behave during severe drug reactions like DRESS and during milder drug rashes. It may help doctors understand what drives organ damage and improve how these reactions are managed.
ArrasAges 18 years+ - NCT04653324Recruiting
Registry for people with diagnosed food allergies
This registry aims to collect information from people who already have a diagnosed food allergy. Joining may help researchers better understand food allergy patterns and needs.
McLean, VirginiaAges Any age
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Common questions
- Are there clinical trials for hypersensitivity?
- Yes. Clin2 currently lists 58 recruiting hypersensitivity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a hypersensitivity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a hypersensitivity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.