Clinical trials
Immunocompromised clinical trials
Below are recruiting immunocompromised clinical trials, each written for real people, not researchers. We’re tracking 36 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07379554Recruiting
Infection Risk Prediction After Transplant
This study is for people who have had a stem cell or solid organ transplant. It aims to predict who might get a serious infection and help doctors manage their care better.
Pavia, LombardyAges Any age - NCT07295535Recruiting
Nasal immune responses to respiratory viruses in healthy and immunocompromised people
This study looks at how the nose's immune system responds to common respiratory viruses in both healthy people and those with weakened immune systems. It aims to understand how long these responses last.
Pavia, PaviaAges 18–90 - NCT06890078Recruiting
Better diagnosis of pneumocystis in patients with weak immune systems
This trial tests a new way to diagnose pneumocystis, a lung infection that can affect people with weakened immune systems. It may help find the infection faster and more accurately using samples taken from your lungs.
ParisAges 18 years+ - NCT06615635Recruiting
Radiation device trial for skin cancer in patients with weak immune systems
This trial tests a special radiation device (DaRT) placed directly into skin cancer tumors. It is designed for patients with weakened immune systems (immunocompromised) who have a single skin cancer lesion on the skin (not spread elsewhere).
Gilbert, ArizonaAges 18 years+ - NCT06599658RecruitingPhase 2
COVID-19 booster and flu vaccine timing for people with weak immune systems
This study tests the best timing for a COVID-19 booster and flu shot in people with weakened immune systems, such as organ transplant recipients, people living with HIV, or those with certain autoimmune conditions. It aims to help patients get better protection from both vaccines.
Montreal, QuebecAges 18 years+ - NCT06387667Recruiting
Fungal lung infections in ICU patients with weak immune systems
This study looks at different types of fungi that may cause serious lung infections in patients with weakened immune systems in the ICU. It aims to find out which fungi are present and which antifungal drugs can kill them.
AsyutAges 18 years+ - NCT03808922RecruitingPhase 3
DAS181 treatment for COVID-19 lung infection in immune-compromised adults
This Phase 3 trial tests DAS181 to treat lower lung (chest) viral infections in people with weakened immune systems, including a COVID-19 subgroup. It may help by targeting certain viruses in the lungs, but joining depends on your oxygen needs, recent diagnosis, and other safety factors.
Duarte, CaliforniaAges Any age - NCT03425526RecruitingPhase 1
Donor T-cell treatment for adenovirus illness in immune-weakened people
This early-phase study tests donor immune cells (T cells) to treat people who have adenovirus infection or adenovirus-related disease but have a weakened immune system. It may help your body fight the virus, especially in cases where other treatments may not be enough.
Houston, TexasAges Any age - NCT06069505Recruiting
Testing for drug-resistant fungus in blood or fluid
This study is testing a new blood or fluid test that may find drug-resistant fungus in people with a weakened immune system who have a serious lung infection. The results could help doctors choose the right medicine faster.
Rotterdam, South HollandAges 18 years+ - NCT07768345RecruitingPhase 3
Revaccination with RSV vaccine for immunocompromised adults
This trial studies whether giving a booster dose of the RSV vaccine (Abrysvo) is safe and effective for adults with weakened immune systems. It includes people who have never had an RSV vaccine and those who had one or two doses in the past.
Los Angeles, CaliforniaAges 18 years+ - NCT07682766Recruiting
Biomarkers of inflammation and infection in critical care
This study looks at markers of inflammation, infection, and immunity in patients who are in the critical care area. It aims to find early signs of how severe the illness might become, how well treatments work, and if infections will develop.
TorinoAges 18 years+ - NCT06597916RecruitingPhase 2
RSV vaccine study for people with weakened immune systems
This study tests how well an RSV vaccine (Arexvy) works in people whose immune systems are weakened by certain cancers, autoimmune diseases, or treatments. It aims to see if the vaccine can protect these vulnerable groups from respiratory infections.
ViennaAges 18 years+ - NCT07529171Recruiting
Monitoring hepatitis B reactivation in immunosuppressed patients
This study tracks patients who carry hepatitis B antibodies and are about to start immunosuppressive therapy (medications that weaken the immune system). Researchers want to understand when and how hepatitis B can reactivate in these patients and how to prevent it.
AdanaAges 18–80 - NCT05862454Recruiting
Magnesium shots may help avoid steroid during certain immune health issues
This trial studies whether giving a magnesium injection can replace (or avoid) steroids during treatment around times of vaccine, a viral infection, or immune system weakness. It targets adults with long-term (chronic) pain who already receive injection-based treatments and can reliably track symptoms.
Surrey, British ColumbiaAges 20–99 - NCT07406217RecruitingPhase 2
Optimizing antivirals for immunocompromised COVID-19 patients
This trial tests whether an optimized antiviral treatment can help people with weakened immune systems who have COVID-19. It aims to find the best way to treat them to prevent severe illness.
Basel, BaselAges 16 years+ - NCT07388615RecruitingPhase 2
Echinacea for cryptosporidiosis in children with weak immune systems
This trial tests whether the herb echinacea (Immulant) can help treat cryptosporidiosis, a diarrheal infection, in children aged 5 to 12 whose immune systems are weakened. It aims to find a safe and effective treatment for these children.
CairoAges 5–12 - NCT07321808Recruiting
Shingles vaccine study for frail patients
This study tests how well the shingles vaccine works in people with weakened immune systems due to conditions like rheumatoid arthritis, cancer, or multiple sclerosis. It aims to see if the vaccine is safe and effective for these patients.
Pavia, PaviaAges Any age - NCT07299500Recruiting
Toxoplasmosis study in non-HIV immune compromised patients
This study looks at toxoplasmosis infections in people with weakened immune systems (not caused by HIV). It aims to learn more about how these infections happen and how they affect patients.
StrasbourgAges 18 years+ - NCT07120464Recruiting
Rabies vaccine study for people with weak immune systems or older age
This study tests how well a rabies vaccine works and how safe it is for people whose immune systems may be weaker, such as those with certain long-term illnesses, organ transplants, or age 60 and older. It compares them to healthy adults ages 18 to 59.
Shenzhen, GuangdongAges Any age - NCT07110636Recruiting
Blood test for infection in immunocompromised adults
This trial tests a blood test that looks for infection by analyzing tiny bits of DNA from microbes. It may help find infections faster in people with weakened immune systems, such as transplant recipients or those with blood cancers.
San Francisco, CaliforniaAges 18 years+ - NCT07050732RecruitingPhase 2
Testing RSV vaccine in people with weakened immune systems
This study tests an RSV vaccine in people with weakened immune systems (like transplant recipients) and in older adults. It aims to see how well the vaccine boosts protection against RSV, a common respiratory virus.
Baltimore, MarylandAges 18 years+ - NCT07013474RecruitingPhase 3
Study of ibuzatrelvir for immunocompromised adults with COVID-19
This trial tests an investigational medicine called ibuzatrelvir for adults with COVID-19 who have a weakened immune system. The study aims to see if it helps them recover and avoid severe illness.
Canoga Park, CaliforniaAges 18 years+ - NCT07013370Recruiting
Preventing CMV in Children After Stem Cell Transplant
This trial tests whether a special antibody treatment (CMV-specific immunoglobulin) can prevent CMV infections in children who have had a stem cell transplant from a donor. It may help protect your child’s immune system during recovery.
TriesteAges 1 month–18 years - NCT06817889RecruitingPhase 2
Remdesivir for RSV in people with weak immune systems
This trial tests if remdesivir can safely treat RSV (a respiratory virus) in people with weakened immune systems, such as those who have had a stem cell or bone marrow transplant, CAR T-cell therapy, or are being treated for blood cancer. If you have a confirmed RSV infection in your nose or throat and are at moderate or high risk for complications, you may be able to join.
Duarte, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for immunocompromised?
- Yes. Clin2 currently lists 36 recruiting immunocompromised studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a immunocompromised trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a immunocompromised trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.