Clinical trials
Immunodeficiency clinical trials
Below are recruiting immunodeficiency clinical trials, each written for real people, not researchers. We’re tracking 123 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07312266Recruiting
Questioning asymptomatic TB in HIV patients
This study looks for tuberculosis (TB) in people with HIV who have no symptoms. It aims to understand how common hidden TB is, which could lead to better detection and prevention.
Manhiça, Maputo ProvinceAges 18 years+ - NCT07279376Enrolling by invitation
Using an algorithm to improve HIV care for health home members
This study tests a computer-based algorithm to help improve HIV care for people who are part of a special care management program called a Health Home. It aims to make sure you get the support and treatment you need.
New York, New YorkAges 18 years+ - NCT07266831RecruitingPhase 2/Phase 3
New HIV treatment for people not yet on medication
This study tests a new combination medicine for people with HIV who have never taken treatment. It aims to see if it is safe and helps reduce the amount of virus in the blood.
Los Angeles, CaliforniaAges 18 years+ - NCT07261891Recruiting
Lab study of JAK-STAT related disorders
This study looks at blood or tissue samples from people with certain genetic disorders that affect a key cell communication pathway (JAK-STAT). The goal is to learn more about these disorders and test potential treatments in the lab.
Leuven, Vlaams-BrabantAges 18 years+ - NCT07251179Recruiting
Understanding immune cells in autoimmune diseases and immune deficiencies
This study looks at immune cells in people with certain autoimmune diseases or immune deficiencies. The goal is to understand how these cells work, which may help improve future treatments.
StrasbourgAges 18–70 - NCT07221123RecruitingPhase 2
Smell and memory training for brain health
This study tests whether smell exercises can improve memory and thinking in people who are worried about their brain health. If you are 40 or older and have mild memory concerns, you may be able to join.
Birmingham, AlabamaAges 40 years+ - NCT07209917Recruiting
Cervical cancer prevention for women with HIV and HPV
This trial tests a new way to prevent cervical cancer in women with both HIV and HPV. It focuses on women in India who are already on stable HIV treatment and have a normal cervical exam.
Bangalore, KarnatakaAges 25–50 - NCT05266898RecruitingPhase 4
HPV vaccine response study for people living with HIV
This trial studies how well the Gardasil-9 HPV vaccine triggers the body’s immune response in people living with HIV. It may help doctors understand the best way to protect against HPV-related cancers and infections in this population.
New Orleans, LouisianaAges 18–65 - NCT06278337Recruiting
Moesin-associated immunodeficiency study
This study looks at a rare immune system condition caused by changes in the MOESIN gene. It aims to better understand the condition and may help develop future treatments.
Bethesda, MarylandAges 4–80 - NCT07160075RecruitingPhase 4
HIV prevention with PrEP for people on opioid therapy
This trial tests if daily PrEP medication can help prevent HIV in people receiving opioid replacement therapy. You must be HIV-negative and regularly attend your opioid treatment program to join.
Calgary, AlbertaAges 16 years+ - NCT07143968RecruitingPhase 2
Resmetirom for people with MASLD and HIV
This study tests if resmetirom can help people who have both HIV and a liver condition called MASLD (fat buildup in the liver not caused by alcohol). You may qualify if your liver has a certain amount of fat and stiffness, and your HIV is well controlled with stable medication.
Birmingham, AlabamaAges 18 years+ - NCT07119359Recruiting
TB and HIV prevention study for households in Uganda
This study tests whether adding HIV prevention services to routine TB household contact checks can help more people stay healthy. If you or someone you live with has TB, you may be able to join.
KampalaAges 15 years+ - NCT07118683Recruiting
Brazilian health study for people with HIV or AIDS
This study is creating a record of chronic health conditions (like heart disease, diabetes, or high blood pressure) in people living with HIV or AIDS in Brazil. Joining helps researchers better understand and care for the health needs of people like you.
Goiânia, GoiásAges 18 years+ - NCT07089966Recruiting
PrEP delivery in family planning clinics
This trial tests a program where HIV testing counselors help family planning patients learn about and get PrEP, a daily pill that prevents HIV. It aims to make PrEP easier to access in clinics you may already visit.
KisumuAges 15 years+ - NCT07075146RecruitingPhase 3
Comparing two HIV treatments for people with overweight or obesity
This trial compares two different daily pill combinations for people newly starting HIV treatment who are overweight or have obesity. It aims to see which one works better for controlling the virus and managing weight.
Mexico CityAges 18–70 - NCT07064928Enrolling by invitation
Reducing HIV stigma in pregnancy and after birth
This study tests a program to reduce stigma related to HIV among pregnant women and new mothers. You may be eligible if you are living with HIV, are between 24 and 36 weeks pregnant, and plan to stay in the area for at least 6 months after your baby is born.
AccraAges 14 years+ - NCT07062614Recruiting
Hair test for HIV treatment adherence
This study uses hair samples to see if they can tell if someone is taking their HIV medication regularly. If you've been on a stable HIV pill regimen for at least 6 months, this study may help improve monitoring for other patients.
ToulouseAges 18–70 - NCT07030920RecruitingPhase 2
Reducing inflammation in people living with HIV
This trial tests if a drug can lower inflammation in people with HIV who are on effective treatment. It may help reduce the risk of heart disease and other problems related to chronic inflammation.
Montreal, QuebecAges 18 years+ - NCT06999954Recruiting
Global survey for Shwachman-Diamond syndrome and related conditions
This trial is a global survey and registry for people with Shwachman-Diamond Syndrome and related inherited blood disorders. It aims to connect patients, families, and researchers to better understand these conditions and improve care.
Woburn, MassachusettsAges Any age - NCT06980480RecruitingPhase 3
Gammagard to prevent infections in multiple myeloma
This study tests if adding Gammagard (a type of antibody therapy) to your multiple myeloma treatment with Tecvayli can help prevent serious infections. You may qualify if you recently started Tecvayli and are still responding to it.
Mobile, AlabamaAges 18 years+ - NCT05642858Recruiting
Learn heart health tips for people living with HIV
This study tests a text-message education program to help people living with HIV manage cardiovascular (heart and blood vessel) health. It may be helpful if you are 40 or older and can use a smartphone to receive messages.
San Francisco, CaliforniaAges 40 years+ - NCT05786547RecruitingPhase 3
Varenicline plus support to help quit tobacco in HIV care
This Phase 3 trial tests a quit-smoking program using varenicline (a medicine) plus additional support, for people with HIV who currently use tobacco. It may help you stop smoking or using tobacco and stay quit with safer, guided care.
Aurora, ColoradoAges 18 years+ - NCT06880705Recruiting
Trans-Led Care Study for alcohol and drug support
This study is testing a program designed by and for transgender adults to help with alcohol or drug use problems. It looks at whether a supportive, community-based approach can improve health and well-being.
Chicago, IllinoisAges 18 years+ - NCT06886971Recruiting
Strategies to help youth with HIV stay virally suppressed
This trial tests a strategy to help young people with HIV keep their virus levels low. It focuses on using a long-acting injectable medication combination (Cabotegravir and Rilpivirine) and requires communication with your HIV doctor.
Baltimore, MarylandAges 12–30
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Common questions
- Are there clinical trials for immunodeficiency?
- Yes. Clin2 currently lists 123 recruiting immunodeficiency studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a immunodeficiency trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a immunodeficiency trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.