Clinical trials · Boston, MA
Insomnia clinical trials in Boston
We’re tracking 18 recruiting insomnia studies with a site in or near Boston — including Phase 1/Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies near Boston
- NCT06559306RecruitingPhase 3
Seltorexant for depression with insomnia symptoms
This trial tests if adding seltorexant to your current antidepressant can improve depression and sleep problems. It is for people with major depressive disorder who still have symptoms, especially insomnia, despite trying at least one antidepressant.
Boston, MassachusettsAges 18–74 - NCT06736548Enrolling by invitation
Sleep treatment program for cancer survivors
This study tests a sleep education program for cancer survivors who have trouble sleeping. You will learn strategies to improve your sleep and overall well-being.
Boston, MassachusettsAges 18–89 - NCT06807086Recruiting
Online talk therapy for insomnia in cancer survivors
This study tests if online therapy sessions can help cancer survivors with long-term sleep problems (insomnia). It is for people who have finished or are still in active cancer treatment, including those with stable metastatic cancer.
Boston, MassachusettsAges Any age - NCT05674357Recruiting
Training therapists to help people with cancer distress
This trial trains therapists in evidence-based treatments to reduce distress related to cancer and cancer care. You may be able to join if you’re being treated or followed at MGH Cancer Center and your distress level is high.
Boston, MassachusettsAges 18 years+ - NCT06336525Enrolling by invitation
Sleep health in rural Appalachia and Mississippi Delta
This study examines how sleep is linked to heart and metabolic health in people living in rural Appalachia and the Mississippi Delta. If you are already part of the RURAL Study, you may be able to join this sleep-focused part of the research.
Boston, MassachusettsAges 25–65 - NCT07136415RecruitingPhase 4
Comparing digital therapy, trazodone, and daridorexant for menopause insomnia
This trial tests three different treatments for insomnia that started or got worse during the menopausal transition. One is a digital therapy app, and the others are two different medications. The goal is to see which works best for women aged 40–62 who are in the early stages of menopause.
Boston, MassachusettsAges 40–62 - NCT04278404Recruiting
Drug safety study for children already on certain medicines
This study measures how certain medicines move through the body and checks their safety in children. It may help doctors better understand dosing and side effects in kids who are already receiving these treatments, or in some kids who recently tested positive for COVID-19.
Boston, MassachusettsAges birth–20 years - NCT05393830Recruiting
Study tests how sleep loss affects emotion control
This study looks at how losing sleep changes a person’s ability to manage emotions. You may need to do brain scans (fMRI), and you would be asked to avoid alcohol and recreational drugs during the study.
Boston, MassachusettsAges 18–40 - NCT06687161Recruiting
Treating insomnia in mild memory problems
This study tests whether a non-invasive brain stimulation method (TMS) combined with cognitive training can improve sleep in older adults with mild memory issues. It may help if you have trouble falling or staying asleep and have early memory changes.
Boston, MassachusettsAges 60 years+ - NCT05759065Recruiting
Behavioral insomnia treatment for adults with limited resources
This study tests behavioral (non-medication) treatments to help adults with insomnia who have socioeconomic disadvantages access better care through primary care clinics. You may be asked about sleep symptoms, mental health, substance use, and daily schedule to see if the treatment is safe and likely to help you.
Boston, MassachusettsAges 18 years+ - NCT06972303RecruitingPhase 1/Phase 2
Mindfulness meditation for insomnia
This trial tests if a mindfulness meditation program, delivered through a mobile app, can help people with chronic insomnia fall asleep faster. You will use your own smartphone or tablet to follow the program and report your sleep.
Boston, MassachusettsAges 18 years+ - NCT06375265Recruiting
Sleep improvement program for older surgery patients
This trial tests a digital sleep improvement program for older adults who are about to have knee or hip replacement surgery. It aims to help you sleep better before and after surgery, which may improve your brain health and recovery.
Boston, MassachusettsAges 65 years+ - NCT07071324Recruiting
CF Wellness Program for Fatigue
This wellness program tests if coaching sessions can help people with cystic fibrosis who feel tired. It is a remote program you can join using your phone or computer, as long as you get CF care at a participating center.
Boston, MassachusettsAges 18 years+ - NCT05124392Recruiting
Observational study of biomarkers in people at risk for prion disease
This study looks for early signs of prion disease in people who are at risk, using blood tests, spinal fluid, and thinking tests. It hopes to find ways to diagnose and track the disease earlier.
Charlestown, MassachusettsAges 18–85 - NCT06976138Recruiting
Using Light or ions to Improve Sleep and Pain After Knee Surgery
This study tests whether a special bright light or negative ion therapy can help older adults sleep better and have less pain after knee replacement surgery. It's for people with knee arthritis who already have trouble sleeping and are scheduled for one knee replacement.
Chestnut Hill, MassachusettsAges 60 years+ - NCT06953869RecruitingPhase 3
Testing a sleep medicine for children with insomnia
This study tests if the drug tasimelteon helps children with insomnia sleep better compared to a placebo (a pill with no medicine). It is for children aged 2 to 17 who have been diagnosed with insomnia that is not caused by another medicine.
Worcester, MassachusettsAges 2–17 - NCT06737055Recruiting
Sleep help for new and expectant parents
This study tests a sleep program for pregnant women and new moms. It uses specially trained helpers to teach better sleep habits, which may improve your rest and well-being.
Providence, Rhode IslandAges 18–99 - NCT06655883RecruitingPhase 3
Testing suvorexant for insomnia in people with opioid use disorder
This study tests whether the sleep medication suvorexant (Belsomra) can help people with opioid use disorder who also have trouble sleeping. If you are stable on medication for opioid use disorder and have not used opioids in the last month, this trial may be an option for you.
Providence, Rhode IslandAges 18–70
Hear when a new Insomnia trial opens near Boston, MA
We’ll email you when one opens near Boston, MA — at most once a week, no account needed, unsubscribe anytime.
Insomnia trials in other cities
Where these studies are running near Boston
Institutions with a site for the recruiting insomnia studies listed above.
- Brigham and Women's Hospital · 4 studies
- Massachusetts General Hospital · 4 studies
- Beth Israel Deaconess Medical Center · 2 studies
- Boston Children's Hospital · 2 studies
- Rhode Island Hospital · 2 studies
- Adams Clinical
- Alzheimer's Clinical and Translational Research Unit
- Boston Clinical Trials
What taking part in a insomnia study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting insomnia studies in Massachusetts.
Common questions
- Are there insomnia clinical trials near Boston?
- Yes. We're currently tracking 18 recruiting insomnia studies with a site near Boston, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a insomnia study near Boston?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Boston to take part?
- Not necessarily. These studies have a site near Boston, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a insomnia trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New insomnia studies open near Boston regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.