Observational study of biomarkers in people at risk for prion disease
Part of Brain & nervous system, Infections clinical trials.
This study looks for early signs of prion disease in people who are at risk, using blood tests, spinal fluid, and thinking tests. It hopes to find ways to diagnose and track the disease earlier.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 85 years old.
- You must be at genetic risk for prion disease (carry the gene mutation or have a parent and other relatives with the disease).
- You must be able to have blood draws, a spinal tap (lumbar puncture), and thinking tests.
- You must be fluent in English.
- You must not have other brain diseases like stroke, Parkinson's, or Alzheimer's.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study is a registry for people who may be at risk for genetic prion disease because of their family history. It involves genetic testing and follow-up visits to track health over time.
This study tests an RNA-based drug designed to turn off the gene that causes prion disease. It aims to see if the drug is safe in people with early-stage symptoms.
This study looks at genetic factors in people with PSP, CBS, MSA, or similar brain conditions, and also in their family members. It involves genetic testing to learn more about these diseases and may help find new treatments.
This study collects information from patients diagnosed with Creutzfeldt-Jakob Disease (CJD), a rare brain condition, to better understand how it develops and progresses. Researchers will review your medical records, blood tests, brain scans, and other clinical data to identify patterns that could help future patients.
This study follows people who have a close family member with inherited Creutzfeldt-Jakob disease (CJD) to understand how the disease develops before any symptoms. It may involve genetic testing and safety-required procedures like brain scans and a spinal fluid test to learn about early changes.
This study looks at how your symptoms, brain imaging (MRI), and genetic factors relate to neurodegenerative conditions. It may help researchers better understand what causes these illnesses and how to classify them.
Hear when a new CJD (Creutzfeldt Jakob Disease) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.