Clinical trials
Irritability clinical trials
Below are recruiting irritability clinical trials, each written for real people, not researchers. We’re tracking 141 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07481422RecruitingPhase 1/Phase 2
Fecal transplant capsules for irritable bowel syndrome
This trial tests whether taking capsules containing freeze-dried healthy donor stool can improve symptoms of irritable bowel syndrome (IBS) that haven't gotten better with usual treatments. It aims to see if this approach is safe and helpful for people with moderate to severe IBS.
RijekaAges 18–65 - NCT06783894Recruiting
Elliptical Exercise for Sexual Health in Men with IBS
This study looks at whether regular elliptical exercise can help improve sexual function in married men who have both irritable bowel syndrome (IBS) and erectile dysfunction. It may be an option if you are looking for a drug-free way to manage these issues.
Dokki, Giza GovernorateAges 30–50 - NCT07471490Enrolling by invitation
Stool test study for inflammatory bowel disease vs. irritable bowel syndrome
This study collects stool samples and health information to help develop a new test that may tell the difference between inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS). If you have not been diagnosed with a chronic gut disorder, you may be able to join.
Minneapolis, MinnesotaAges 2 years+ - NCT06636513Recruiting
Testing SMT04 for irritable bowel syndrome
This trial tests a new treatment called SMT04 for people with irritable bowel syndrome (IBS), specifically the diarrhea or mixed types. It may help reduce symptoms like abdominal pain and changes in bowel habits.
Singapore, SingaporeAges 21–55 - NCT03687814Recruiting
Low FODMAP diet plus PEG for IBS with constipation
This study tests whether a low-FODMAP diet combined with PEG 3350 can reduce symptoms in adults with IBS-C (irritable bowel syndrome with constipation). It may help improve bowel habits and abdominal pain, and it checks which people can safely follow the diet and treatment plan.
Ann Arbor, MichiganAges 18 years+ - NCT07345377Enrolling by invitation
Personalized brain stimulation for irritable bowel syndrome
This study uses brain stimulation (TMS) customized for each person to treat IBS. It uses MRI scans to see how the brain responds, aiming to find better ways to predict who will benefit from this therapy.
Hangzhou, ZhejiangAges 18–75 - NCT05803993Recruiting
Fecal transplant to ease constipation in irritable bowel syndrome
This trial tests whether transferring stool bacteria to the gut (fecal microbiota transplantation) can reduce symptoms of irritable bowel syndrome with constipation. It may help by changing the gut microbiome, but you must meet safety and health requirements.
RomaAges 18 years+ - NCT05803980Recruiting
Fecal transplant to ease IBS diarrhea symptoms
This study tests whether fecal microbiota transplantation (a stool-based treatment to change gut bacteria) can reduce symptoms of irritable bowel syndrome (IBS) that comes with diarrhea. You may be eligible if you’re an adult with diarrhea-predominant IBS and recent colonoscopy results that rule out other intestinal diseases.
RomaAges 18 years+ - NCT06869928Recruiting
Pain and irritability pathway for children with neurological conditions
This study tests a special care plan for children who have both a significant neurological condition and unexplained pain or irritability. The goal is to help families and doctors work together to better understand and manage these distressing symptoms.
Vancouver, British ColumbiaAges 6 months–18 years - NCT07235215Recruiting
Testing Vivatlac for Irritable Bowel Syndrome
This study tests a product called Vivatlac to see if it can help people with Irritable Bowel Syndrome (IBS). If you have moderate-to-severe IBS and haven't taken probiotics or antibiotics recently, you may be able to join.
JarocinAges 18–65 - NCT07176078Recruiting
Osteopathic care plus low-FODMAP diet for fibromyalgia and IBS
This trial tests whether adding osteopathic care (a hands-on therapy) to a low-FODMAP diet helps people with both fibromyalgia and irritable bowel syndrome feel better. It compares the diet alone to the diet plus osteopathic sessions.
Brussels, Brussels CapitalAges 18 years+ - NCT07168434RecruitingPhase 3
Yeast supplement for irritable bowel syndrome (IBS)
This trial tests if a yeast supplement called Saccharomyces boulardii can help people with irritable bowel syndrome (IBS), except for those with constipation as their main symptom. Participants take the supplement and see if their symptoms improve.
BragaAges 18–65 - NCT06104631Recruiting
Testing a treatment for IBS-like symptoms in Crohn's remission
This study tests whether a new treatment can reduce IBS-like symptoms, such as belly pain and bloating, in people whose Crohn's disease is in remission. It aims to improve your quality of life without targeting active Crohn's inflammation.
LiègeAges 18–75 - NCT07149519Recruiting
Diet and probiotics for endometriosis and IBS
This study tests whether dietary guidance and probiotics can help women with endometriosis and irritable bowel syndrome (IBS). It aims to see if these treatments improve symptoms and quality of life.
Catanduva, São PauloAges 15–50 - NCT07125625Recruiting
Probiotic mixture for children with irritable bowel syndrome
This study tests whether a mixture of two friendly bacteria (probiotics) can improve belly pain and other IBS symptoms in children. If your child qualifies, they may receive the probiotic mixture or a placebo for a period of time.
Bari, BariAges 4–18 - NCT07114055RecruitingPhase 2/Phase 3
Ebastine for diarrhea-predominant IBS
This trial tests whether ebastine, an allergy medicine, can help relieve symptoms of diarrhea-predominant irritable bowel syndrome (IBS-D). If you have IBS-D and are at least 18, this study may offer a new option to manage your condition.
DhakaAges 18 years+ - NCT07039747RecruitingPhase 2
Can a dietary supplement help people with irritable bowel syndrome?
This trial is testing if a dietary supplement can reduce symptoms of irritable bowel syndrome (IBS). You might qualify if you have been diagnosed with IBS, have moderate to severe symptoms, and are between 18 and 75 years old.
Rouen, FranceAges 18–75 - NCT06940596Recruiting
Comparing diets and therapies for irritable bowel syndrome
This study compares different dietary and behavioral treatments to find out which works best for different people with irritable bowel syndrome (IBS). You'll be asked to follow a specific treatment program to see how it affects your symptoms.
Melbourne, VictoriaAges 18 years+ - NCT06900491Recruiting
Irritable Bowel Syndrome Regional Cohort Study
This study follows a group of people with irritable bowel syndrome (IBS) to learn more about the condition. You may join if you have been diagnosed with IBS and have had normal routine blood tests.
AmiensAges 18 years+ - NCT06871488RecruitingPhase 4
ADHD irritability & aggression treatment with stimulants
This study tests whether CNS stimulant medications can improve irritability and aggression in children with ADHD. It looks for factors that predict who will benefit most.
Hershey, PennsylvaniaAges 7–12 - NCT06801184Recruiting
Gut bacteria study for constipation-predominant IBS with methane
This study looks at the gut bacteria in people with irritable bowel syndrome (IBS) who have constipation and produce high levels of methane gas. It aims to understand how methane relates to symptoms and may guide future treatments.
LyonAges 18 years+ - NCT06788444Recruiting
Esketamine for irritable bowel syndrome with anxiety or depression
This study tests if esketamine, a fast-acting medication, can help people with irritable bowel syndrome who also have anxiety or depression. It is given during a colonoscopy to see if it reduces your IBS symptoms.
Beijing, Beijing MunicipalityAges 18–60 - NCT06757491Recruiting
Low frequency brain stimulation for diarrhea-predominant IBS pain
This trial tests if a type of brain stimulation called low-frequency repetitive transcranial magnetic stimulation (lf-rTMS) can reduce belly pain in people with irritable bowel syndrome that causes diarrhea (IBS-D). It is a non-invasive treatment that uses magnetic pulses to target areas of the brain involved in pain perception.
Suzhou, JiangsuAges 18–75 - NCT06706674RecruitingPhase 3
Testing lumateperone for irritability in teens with autism
This study tests an investigational medication called lumateperone to see if it can reduce irritability in children and teens with autism. It is for teenagers aged 13–17 whose irritability is causing significant problems.
Little Rock, ArkansasAges 5–17
Hear when a new Irritability trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for irritability?
- Yes. Clin2 currently lists 141 recruiting irritability studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a irritability trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a irritability trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.