Clinical trials
Irritability clinical trials
Below are recruiting irritability clinical trials, each written for real people, not researchers. We’re tracking 148 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05680766Recruiting
Exercise training to improve IBS symptoms in inactive people
This trial tests whether a structured exercise program can improve symptoms in people with irritable bowel syndrome (IBS) who currently live a mostly sedentary, inactive lifestyle. It focuses on safety and feasibility (whether the program can be done and what symptom changes may occur).
JetteAges 18–60 - NCT05719246Recruiting
Yoga and meditation for teens with IBS stress
This study tests a structured yoga and meditation program to help reduce stress symptoms in teens with irritable bowel syndrome (IBS). It may help your teen learn calming practices that could ease how stress affects IBS.
Camden, New JerseyAges 12–21 - NCT05721742Recruiting
Virtual diet education for irritable bowel symptom management
This trial tests whether adding online (virtual) diet education to a step-by-step irritable bowel (IBS) care plan can improve symptoms like belly pain and stool changes. You may be asked to make diet changes and use a device to join the virtual education.
Halifax, N.S.Ages 18–65 - NCT05730491Recruiting
Online parenting program for kids with IBS-related belly pain
This trial tests an online social learning program to help parents support their child when the parent has irritable bowel syndrome (IBS) or related belly pain. It may help families build coping skills and resilience through guided parent sessions.
Seattle, WashingtonAges 18 years+ - NCT05740319Recruiting
Test stool transplant to treat irritable bowel syndrome
This trial studies fecal microbiota transplantation, which is transferring stool bacteria from a healthy donor to help rebalance gut microbes. If you have irritable bowel syndrome (IBS) that hasn’t improved after several standard treatments, this study may see whether it reduces your symptoms and is safe.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT05803993Recruiting
Fecal transplant to ease constipation in irritable bowel syndrome
This trial tests whether transferring stool bacteria to the gut (fecal microbiota transplantation) can reduce symptoms of irritable bowel syndrome with constipation. It may help by changing the gut microbiome, but you must meet safety and health requirements.
RomaAges 18 years+ - NCT05803980Recruiting
Fecal transplant to ease IBS diarrhea symptoms
This study tests whether fecal microbiota transplantation (a stool-based treatment to change gut bacteria) can reduce symptoms of irritable bowel syndrome (IBS) that comes with diarrhea. You may be eligible if you’re an adult with diarrhea-predominant IBS and recent colonoscopy results that rule out other intestinal diseases.
RomaAges 18 years+ - NCT05972317Recruiting
Study gut bacteria in IBS patients with and without treatment
This study looks at stool (poop) samples to understand differences in gut bacteria in people with irritable bowel syndrome (IBS), depending on whether they’ve had treatment. It may help researchers find better ways to explain IBS and improve care.
RehovotAges 18–70 - NCT06090110Recruiting
Vagus nerve stimulation for irritable bowel syndrome
This study tests whether a gentle electrical device that stimulates the vagus nerve can help relieve symptoms of irritable bowel syndrome. If you have IBS and are between 18 and 75, you may be able to join.
Maastricht, LimburgAges 18–75 - NCT06271538RecruitingPhase 4
Skal Pro Powder for IBS symptoms
This study tests if Skal Pro Powder, a probiotic, can help relieve symptoms of Irritable Bowel Syndrome (IBS). It is for adults with any type of IBS who haven't used certain other treatments recently.
Kubang Kerian, KelantanAges 18 years+ - NCT06291038Recruiting
Glutamine for IBS with leaky gut
This trial tests whether a supplement called glutamine can help people with irritable bowel syndrome (IBS) who have increased gut permeability (leaky gut). It aims to see if taking glutamine improves digestive symptoms and quality of life.
AmiensAges 18–75 - NCT06473454Recruiting
Physiotherapy for irritable bowel syndrome
This study is testing whether a special physiotherapy program focused on posture and movement can help ease symptoms of Irritable Bowel Syndrome. It is for people who want a non-drug treatment option and are willing to participate in exercise sessions.
IstanbulAges 18–65 - NCT06489444Recruiting
Fecal amino acids, gut taste receptors, and IBS
This study looks at how amino acids in stool and taste receptors in the gut relate to irritable bowel syndrome (IBS). It aims to better understand IBS and may help find new ways to manage symptoms.
Xi'an, ShaanxiAges 18–80 - NCT06636513Recruiting
Testing SMT04 for irritable bowel syndrome
This trial tests a new treatment called SMT04 for people with irritable bowel syndrome (IBS), specifically the diarrhea or mixed types. It may help reduce symptoms like abdominal pain and changes in bowel habits.
Singapore, SingaporeAges 21–55 - NCT06647043Recruiting
Can synbiotics help irritable bowel syndrome?
This study tests whether a synbiotic (a mix of good bacteria and fiber) can improve symptoms of irritable bowel syndrome (IBS), especially for people with diarrhea-predominant or mixed type IBS, or functional diarrhea.
Kubang Kerian, KelantanAges 18–70 - NCT06705153Recruiting
Laughter yoga for irritable bowel syndrome
This study tests whether laughter yoga can help reduce IBS symptoms like belly pain and bloating, and also improve mood, sleep, and overall quality of life. You would join video calls where you practice special laughing exercises (no jokes needed) and then answer questionnaires.
Erzurum, YakutiyeAges 18–90 - NCT07545759RecruitingPhase 2
Testing brenipatide for IBS with diarrhea symptoms
This study tests whether a new medication called brenipatide can help people with IBS-diarrhea (IBS-D) reduce belly pain and loose stools. IBS-D is a condition where the intestines move too quickly, causing frequent diarrhea and discomfort.
Mesa, ArizonaAges 18–75 - NCT07545772RecruitingPhase 2
Testing Brenipatide for Constipation-Focused IBS
This trial tests a new medicine called brenipatide to see if it can help people with IBS-C (irritable bowel syndrome with constipation). The study focuses on whether the drug reduces belly pain and improves bowel movements in people whose main symptom is hard or infrequent stools.
Mesa, ArizonaAges 18–75 - NCT06757491Recruiting
Low frequency brain stimulation for diarrhea-predominant IBS pain
This trial tests if a type of brain stimulation called low-frequency repetitive transcranial magnetic stimulation (lf-rTMS) can reduce belly pain in people with irritable bowel syndrome that causes diarrhea (IBS-D). It is a non-invasive treatment that uses magnetic pulses to target areas of the brain involved in pain perception.
Suzhou, JiangsuAges 18–75 - NCT06783894Recruiting
Elliptical Exercise for Sexual Health in Men with IBS
This study looks at whether regular elliptical exercise can help improve sexual function in married men who have both irritable bowel syndrome (IBS) and erectile dysfunction. It may be an option if you are looking for a drug-free way to manage these issues.
Dokki, Giza GovernorateAges 30–50 - NCT06788444Recruiting
Esketamine for irritable bowel syndrome with anxiety or depression
This study tests if esketamine, a fast-acting medication, can help people with irritable bowel syndrome who also have anxiety or depression. It is given during a colonoscopy to see if it reduces your IBS symptoms.
Beijing, Beijing MunicipalityAges 18–60 - NCT06869928Recruiting
Pain and irritability pathway for children with neurological conditions
This study tests a special care plan for children who have both a significant neurological condition and unexplained pain or irritability. The goal is to help families and doctors work together to better understand and manage these distressing symptoms.
Vancouver, British ColumbiaAges 6 months–18 years - NCT06871488RecruitingPhase 4
ADHD irritability & aggression treatment with stimulants
This study tests whether CNS stimulant medications can improve irritability and aggression in children with ADHD. It looks for factors that predict who will benefit most.
Hershey, PennsylvaniaAges 7–12 - NCT06900491Recruiting
Irritable Bowel Syndrome Regional Cohort Study
This study follows a group of people with irritable bowel syndrome (IBS) to learn more about the condition. You may join if you have been diagnosed with IBS and have had normal routine blood tests.
AmiensAges 18 years+
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Common questions
- Are there clinical trials for irritability?
- Yes. Clin2 currently lists 148 recruiting irritability studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a irritability trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a irritability trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.