Clinical trials
Irritability clinical trials
Below are recruiting irritability clinical trials, each written for real people, not researchers. We’re tracking 147 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06940596Recruiting
Comparing diets and therapies for irritable bowel syndrome
This study compares different dietary and behavioral treatments to find out which works best for different people with irritable bowel syndrome (IBS). You'll be asked to follow a specific treatment program to see how it affects your symptoms.
Melbourne, VictoriaAges 18 years+ - NCT07039747RecruitingPhase 2
Can a dietary supplement help people with irritable bowel syndrome?
This trial is testing if a dietary supplement can reduce symptoms of irritable bowel syndrome (IBS). You might qualify if you have been diagnosed with IBS, have moderate to severe symptoms, and are between 18 and 75 years old.
Rouen, FranceAges 18–75 - NCT07149519Recruiting
Diet and probiotics for endometriosis and IBS
This study tests whether dietary guidance and probiotics can help women with endometriosis and irritable bowel syndrome (IBS). It aims to see if these treatments improve symptoms and quality of life.
Catanduva, São PauloAges 15–50 - NCT07168434RecruitingPhase 3
Yeast supplement for irritable bowel syndrome (IBS)
This trial tests if a yeast supplement called Saccharomyces boulardii can help people with irritable bowel syndrome (IBS), except for those with constipation as their main symptom. Participants take the supplement and see if their symptoms improve.
BragaAges 18–65 - NCT07176078Recruiting
Osteopathic care plus low-FODMAP diet for fibromyalgia and IBS
This trial tests whether adding osteopathic care (a hands-on therapy) to a low-FODMAP diet helps people with both fibromyalgia and irritable bowel syndrome feel better. It compares the diet alone to the diet plus osteopathic sessions.
Brussels, Brussels CapitalAges 18 years+ - NCT07235215Recruiting
Testing Vivatlac for Irritable Bowel Syndrome
This study tests a product called Vivatlac to see if it can help people with Irritable Bowel Syndrome (IBS). If you have moderate-to-severe IBS and haven't taken probiotics or antibiotics recently, you may be able to join.
JarocinAges 18–65 - NCT02421705Recruiting
Brain-gut sensitivity study in IBS and inflammatory bowel disease
This study checks how sensitive your gut is to normal stimuli in people with IBS, ulcerative colitis, Crohn’s disease, and in healthy volunteers. Results may help researchers understand why some people feel more abdominal discomfort and how that connects to inflammatory bowel conditions.
Leuven, Vlaams-BrabantAges 18–65 - NCT07481422RecruitingPhase 1/Phase 2
Fecal transplant capsules for irritable bowel syndrome
This trial tests whether taking capsules containing freeze-dried healthy donor stool can improve symptoms of irritable bowel syndrome (IBS) that haven't gotten better with usual treatments. It aims to see if this approach is safe and helpful for people with moderate to severe IBS.
RijekaAges 18–65 - NCT06413004Recruiting
IBS and immune reactions to bacteria in the gut
This study tests whether some IBS symptoms are linked to a certain gut bacteria and an immune reaction. It aims to understand the cause of IBS to find better treatments.
GothenburgAges 18–70 - NCT07517029Recruiting
Gut Bacteria Study in Post-Infectious IBS
This study looks at how gut bacteria may change in people who developed irritable bowel syndrome (IBS) after a stomach infection. Researchers hope to understand why some people recover completely while others develop ongoing digestive problems.
RomeAges 18 years+ - NCT07524439Recruiting
Beta-glucan cream for incontinence-related skin irritation
This study tests whether a special cream containing beta-glucan (a natural ingredient) can soothe and protect skin damaged by urine or stool leakage. You'd apply the cream during a hospital stay of at least one week to see if it helps healing.
Edmonton, AlbertaAges 18 years+ - NCT07540312Recruiting
Compression System for Moderate to Severe Irritable Bowel Syndrome
This trial tests a wearable compression device designed to help people with moderate to severe irritable bowel syndrome (IBS). The device applies variable pressure to the abdomen and may help reduce symptoms like abdominal pain, bloating, and bowel irregularities.
Kissimmee, FloridaAges 18–60 - NCT07584278Recruiting
Probiotics and Biomarkers for Irritable Bowel Syndrome
This study tests whether probiotics (beneficial bacteria) can help reduce irritable bowel syndrome (IBS) symptoms and change certain markers in your gut. You'll take a probiotic supplement for 12 weeks while researchers track how your symptoms and gut health change.
GothenburgAges 18 years+ - NCT07635394Recruiting
Pregabalin for Irritable Bowel Syndrome Relief
This study tests whether pregabalin, a nerve-pain medication, can help reduce irritable bowel syndrome (IBS) symptoms like abdominal pain and irregular bowel habits. Researchers want to see if it's safe and effective for people with mild-to-moderate IBS.
Beijing, Beijing MunicipalityAges 18–70 - NCT07471490Enrolling by invitation
Stool test study for inflammatory bowel disease vs. irritable bowel syndrome
This study collects stool samples and health information to help develop a new test that may tell the difference between inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS). If you have not been diagnosed with a chronic gut disorder, you may be able to join.
Minneapolis, MinnesotaAges 2 years+ - NCT07345377Enrolling by invitation
Personalized brain stimulation for irritable bowel syndrome
This study uses brain stimulation (TMS) customized for each person to treat IBS. It uses MRI scans to see how the brain responds, aiming to find better ways to predict who will benefit from this therapy.
Hangzhou, ZhejiangAges 18–75 - NCT04880876Enrolling by invitationPhase 3
Oral IBS-D medicine trial for kids and teens
This trial tests whether an oral medicine (eluxadoline) can help children and teens with IBS-D, a condition that causes stomach pain and frequent loose stools. It’s a Phase 3 study, meaning it’s designed to confirm benefits and safety.
Corona, CaliforniaAges 6–17 - NCT07655375Recruiting
Study of UCB8600 on gut mast cells in IBS and colorectal cancer
This study looks at how a medicine called UCB8600 affects certain immune cells (mast cells) in the gut. It is for people having colorectal cancer surgery and for patients with irritable bowel syndrome (IBS). The goal is to understand how the medicine works in the body and if it can help with IBS symptoms.
Leuven, Vlaams-BrabantAges 18–65 - NCT07750535Recruiting
Liver fat and scarring in wheat-sensitive patients
This study looks at whether people with non-celiac wheat sensitivity or other digestive conditions have more fat in their liver or liver scarring. It aims to understand if wheat-related issues are linked to liver health.
Palermo, PalermoAges 18–65 - NCT03223077Recruiting
Study of gut germs in new Campylobacter stomach illness
This trial studies how your gut germs (microbiome) and gut lining change during a new bout of Campylobacter infection. It may help researchers understand what drives symptoms and how the gut recovers.
Rochester, MinnesotaAges 18–80 - NCT07749092Recruiting
Kimchi powder for gut health in IBS
This study tests whether taking kimchi powder (a dried form of the fermented cabbage dish) can improve gut health and symptoms in people with diarrhea-predominant IBS. You'll avoid regular kimchi for about 2 months, then take the powder daily and track how you feel.
YangsanAges 20–70 - NCT05796388Recruiting
Virtual reality and linaclotide for IBS with constipation
This study tests whether virtual reality (VR) plus linaclotide can improve symptoms and quality of life in adults with IBS-C (IBS with constipation). You may be asked to use VR and take a study medicine, while doctors check that your IBS diagnosis fits strict criteria.
Jacksonville, FloridaAges 18–70 - NCT01912313Recruiting
Testing nerve signals in gut samples from IBS patients
This study looks at how nerves behave in small gut tissue samples (biopsies) from people with irritable bowel syndrome (IBS) and healthy volunteers. The goal is to better understand IBS symptoms and what might be driving them.
Leuven, Vlaams-BrabantAges 18–99 - NCT07424781Recruiting
Fluoxetine and emotional experience in young adults
This study looks at whether fluoxetine, a common medication for mood, affects how young adults (18-24) experience emotions. It aims to understand emotional processing in healthy individuals without psychiatric history.
Oxford, OxfordshireAges 18–24
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Common questions
- Are there clinical trials for irritability?
- Yes. Clin2 currently lists 147 recruiting irritability studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a irritability trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a irritability trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.