Clinical trials
Irritable Bowel Disease clinical trials
Below are recruiting irritable bowel disease clinical trials, each written for real people, not researchers. We’re tracking 98 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05097872Recruiting
Diet trial for IBS with non-constipation symptoms
This study tests whether a specific diet plan can improve symptoms in people with IBS that is not constipation (IBS-D or IBS-M). If you qualify, you’ll complete symptom questionnaires and follow the study diet for the trial period to see if symptoms improve.
LeuvenAges 18–70 - NCT05293769Recruiting
Food diary questionnaire test for IBS and activity levels
This study checks whether a food questionnaire can reliably estimate what you eat, including certain carbs that can affect digestion (FODMAPs). It also looks at how the results relate to IBS symptoms and your self-reported physical activity.
Jette, Brussels CapitalAges 18–65 - NCT05519683RecruitingPhase 2/Phase 3
Home electrical stimulation for constipation IBS pain
This trial tests whether a home device that uses mild skin electrical stimulation can reduce belly pain from IBS with constipation. It also checks whether the treatment is safe and helpful for symptom relief over the study period.
Ann Arbor, MichiganAges 18 years+ - NCT05525598Recruiting
Online therapy for severe body–mind symptom disorders
This trial tests an internet-based treatment program for people with moderate-to-severe functional somatic disorders (long-lasting physical symptoms linked to how the body and brain interact). It may help reduce symptoms and improve day-to-day functioning by offering structured support online.
Aarhus C, DenmarkAges 18–60 - NCT05776914RecruitingPhase 2
Fecal transplant to treat moderate to severe IBS symptoms
This trial tests whether putting stool (fecal microbiota) from a donor into your bowel can improve symptoms in people with IBS who are not IBS-C. It may help by changing the gut bacteria that can influence IBS symptoms.
Rochester, MinnesotaAges 18–70 - NCT05808036Recruiting
Test a diet app for IBS symptoms using the DOMINO diet
This trial studies whether a specific diet plan delivered through a phone app (the DOMINO diet) can improve symptoms in people with irritable bowel syndrome (IBS). It may help by changing what you eat to reduce gut symptoms, compared with standard care rules in the study.
LeuvenAges 18–70 - NCT05815602RecruitingPhase 3
Ebastine vs mebeverine for non-constipation IBS
This Phase 3 study compares ebastine and mebeverine to see which works better for people with IBS that is not constipation-predominant. If you have IBS symptoms without an underlying intestinal disease, you may be offered one of these medicines and monitored for symptom improvement.
Antwerp, AntwerpenAges 18–65 - NCT05972291Recruiting
Study gut changes in Gulf War illness with chronic stomach symptoms
This study looks at what’s driving Gulf War illness, focusing on gut symptoms like belly pain, diarrhea, and bloating. It may help researchers test approaches aimed at gut barrier function in eligible veterans.
Memphis, TennesseeAges 18–65 - NCT06211062RecruitingPhase 2
Probiotics for chronic fatigue syndrome with IBS
This study tests whether a specific mix of probiotics can help people with chronic fatigue syndrome (ME/CFS) who also have irritable bowel syndrome (IBS). It's a small trial to see if improving gut health can ease symptoms.
Fort Lauderdale, FloridaAges 45–70 - NCT06288672Recruiting
Skin patch test for food allergies in IBS
This study tests whether a skin patch can help identify food allergies in people with irritable bowel syndrome (IBS) whose symptoms are not well controlled. It involves avoiding certain foods and using patches on your back to see if you react.
North Wales, PennsylvaniaAges 18 years+ - NCT06551961Recruiting
How two fibers affect your gut health
This study tests how two types of fiber (inulin and methylcellulose) affect your gut when eaten regularly. You'll eat provided meals and have your breath tested to see how your gut breaks down the fiber.
Nottingham, NottinghamshireAges 18–65 - NCT06684470RecruitingEarly Phase 1
Combining a low-FODMAP diet with medication for IBS-D
This trial tests if a special diet (low-FODMAP) combined with a medication (mirtazapine) can improve IBS with diarrhea symptoms. It is for adults who have not tried these treatments before.
Jacksonville, FloridaAges 18–70 - NCT06727422RecruitingPhase 2
Rifaximin plus NAC for IBS with diarrhea
This trial tests whether a combination of two medications—rifaximin (a gut antibiotic) and NAC (a supplement that helps break down mucus)—can reduce belly pain and diarrhea in people with IBS whose symptoms are not well controlled. It may be an option if other treatments haven't worked well enough.
Los Angeles, CaliforniaAges 18 years+ - NCT06847360Recruiting
Home-based ear stimulation for IBS pain
This trial tests a gentle, non-invasive ear stimulation device (taVNS) used at home to reduce pain from Irritable Bowel Syndrome (IBS). It might help if you have moderate pain most days.
New Haven, ConnecticutAges 18–29 - NCT06866106Recruiting
Well-being in IBS: A phone program for strengths and happiness
This study tests a program that helps people with IBS focus on their strengths and happiness through phone sessions. It aims to see if this approach can improve well-being and manage IBS symptoms.
Boston, MassachusettsAges 18 years+ - NCT06912828Recruiting
Genes and diet for IBS
This trial is studying whether your genes can predict how well a special diet will help your IBS symptoms. If you have moderate to severe IBS and no other diet-related conditions, you may be able to take part.
AthensAges 18–65 - NCT06923800Recruiting
Exercise and Diet Advice for Fibromyalgia and IBS
This study tests whether combining exercise with dietary advice can help people who have both fibromyalgia and irritable bowel syndrome (IBS). It aims to see if this approach improves symptoms and quality of life.
Castellana Grotte, BariAges 30–65 - NCT07000227Recruiting
Low FODMAP diet study for IBS or functional dyspepsia
This study looks at how a low FODMAP diet affects people with irritable bowel syndrome (IBS) or functional dyspepsia (FD). It aims to understand why this diet helps some patients and may offer a way to manage your symptoms.
Kuala Lumpur, Kuala LumpurAges 18 years+ - NCT07235228Recruiting
Synbiotic supplement for irritable bowel syndrome
This trial tests whether a synbiotic (a mix of probiotics and prebiotics) called Vivatlac can improve gut health in people with moderate to severe irritable bowel syndrome (IBS). If you have IBS and are not already taking probiotics or antibiotics, you may be able to join.
JarocinAges 18–65 - NCT07309601Recruiting
Sucrase-isomaltase genes and meal study for IBS
This study looks at how people with irritable bowel syndrome (IBS) handle meals based on their genes for an enzyme that breaks down sugar and starch. It may help explain why some people benefit from a starch- and sugar-reduced diet.
Malmö, Skåne CountyAges 18–70 - NCT07401680RecruitingPhase 1
Stool transplant for active ulcerative colitis
This trial tests whether a stool transplant (fecal microbiota transplantation) can help manage active ulcerative colitis. You would receive a transplant from a healthy donor to see if it improves your symptoms.
Calgary, AlbertaAges 18 years+ - NCT07494968Recruiting
Finding ways to track diet compliance in IBS patients
This study looks for signs in your body—like breath and blood tests—that can show how well you are following a special diet for IBS. It aims to find better ways to track diet compliance, which could help make dietary treatments more effective.
Ann Arbor, MichiganAges 18–65 - NCT07591584Recruiting
Digestive Enzyme Blend for Bloating and Gas Relief
This study tests whether a daily digestive enzyme supplement designed to break down certain hard-to-digest foods can reduce bloating and belly pain. You'll use a smartphone app to track your symptoms over several weeks to see if the enzyme helps.
Los Angeles, CaliforniaAges 18 years+ - NCT07646834Recruiting
Brain-Gut Study of IBS with Anxiety and Depression
This study explores how stress and mood changes affect irritable bowel syndrome (IBS) using brain imaging. Researchers will scan your brain and collect health information to understand the connection between your gut and mental health.
Xi'an, ShaanxiAges 18–60
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Common questions
- Are there clinical trials for irritable bowel disease?
- Yes. Clin2 currently lists 98 recruiting irritable bowel disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a irritable bowel disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a irritable bowel disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.