Clinical trials
Irritable Bowel Syndrome - Diarrhoea clinical trials
Below are recruiting irritable bowel syndrome - diarrhoea clinical trials, each written for real people, not researchers. We’re tracking 104 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05680766Recruiting
Exercise training to improve IBS symptoms in inactive people
This trial tests whether a structured exercise program can improve symptoms in people with irritable bowel syndrome (IBS) who currently live a mostly sedentary, inactive lifestyle. It focuses on safety and feasibility (whether the program can be done and what symptom changes may occur).
JetteAges 18–60 - NCT04880876Enrolling by invitationPhase 3
Oral IBS-D medicine trial for kids and teens
This trial tests whether an oral medicine (eluxadoline) can help children and teens with IBS-D, a condition that causes stomach pain and frequent loose stools. It’s a Phase 3 study, meaning it’s designed to confirm benefits and safety.
Corona, CaliforniaAges 6–17 - NCT07421011RecruitingPhase 1
Comparing two forms of a drug for healthy volunteers
This study tests two different versions of a drug called Trimedat to see if they work the same way in the body. It is for healthy volunteers to understand how the drug is absorbed and if it is safe.
Saint PetersburgAges 18–45 - NCT05754190Recruiting
Smartphone study of mood and symptoms in people with pain
This study uses a smartphone app to track daily pain and mood changes over about 4 months. It’s meant to learn patterns that could help better understand how mood and pain affect each other.
Providence, Rhode IslandAges 18 years+ - NCT04918329Recruiting
Digestive symptom check-in study for adults
This study follows adults with long-lasting “functional” digestive symptoms as part of routine care. It may help researchers better understand these conditions and improve how they are managed.
RouenAges 18 years+ - NCT05972317Recruiting
Personalized diet vs low FODMAP diet for irritable bowel syndrome
This study compares two diet plans for people with irritable bowel syndrome (IBS): a personalized diet tailored to your specific triggers and the low FODMAP diet, which avoids certain carbohydrates that can cause gas and bloating. The goal is to see which approach works better for relieving symptoms.
RehovotAges 18–70 - NCT05652621Recruiting
Probiotics for people with ulcerative colitis symptoms
This study looks at whether probiotic pellets help people with inflammatory bowel disease, specifically ulcerative colitis. It may help improve gut symptoms, but the trial will test how well probiotics work for participants like you.
Xinxiang, HenanAges 18–80 - NCT06215222Recruiting
Studying gut bacteria in IBS and digestive issues
This study uses a tiny capsule to collect samples from your small intestine to learn about gut bacteria in people with IBS or other functional gut disorders. It could help researchers understand what causes digestive symptoms.
Redwood City, CaliforniaAges 18–70 - NCT07750535Recruiting
Liver fat and scarring in wheat-sensitive patients
This study looks at whether people with non-celiac wheat sensitivity or other digestive conditions have more fat in their liver or liver scarring. It aims to understand if wheat-related issues are linked to liver health.
Palermo, PalermoAges 18–65 - NCT07688044Recruiting
How food and bacteria cause belly pain in IBS
This study looks at how certain foods and gut bacteria might trigger abdominal pain in people with Irritable Bowel Syndrome (IBS). If you have IBS and frequent belly pain, you may help researchers understand the link between diet, bacteria, and pain.
Kingston, OntarioAges 18–70 - NCT06665867Recruiting
Video Follow-Up for Kids With Stomach Pain
This trial tests whether video consultations (video calls) are a good option for follow-up appointments in children with functional abdominal pain disorders. It aims to make check-ups easier for families.
AmsterdamAges 4–17 - NCT07656623Recruiting
Probiotics for IBS with stomach issues and stress
This trial tests whether a special probiotic blend can help people with irritable bowel syndrome (IBS) who also have stomach symptoms like heartburn, bloating, or nausea, and feel anxious, depressed, or stressed. It aims to see if the probiotic improves both gut and mood symptoms.
Hanoi, HanoiAges 18 years+ - NCT07655375Recruiting
Study of UCB8600 on gut mast cells in IBS and colorectal cancer
This study looks at how a medicine called UCB8600 affects certain immune cells (mast cells) in the gut. It is for people having colorectal cancer surgery and for patients with irritable bowel syndrome (IBS). The goal is to understand how the medicine works in the body and if it can help with IBS symptoms.
Leuven, Vlaams-BrabantAges 18–65 - NCT07646834Recruiting
Brain-Gut Study of IBS with Anxiety and Depression
This study explores how stress and mood changes affect irritable bowel syndrome (IBS) using brain imaging. Researchers will scan your brain and collect health information to understand the connection between your gut and mental health.
Xi'an, ShaanxiAges 18–60 - NCT06551961Recruiting
How two fibers affect your gut health
This study tests how two types of fiber (inulin and methylcellulose) affect your gut when eaten regularly. You'll eat provided meals and have your breath tested to see how your gut breaks down the fiber.
Nottingham, NottinghamshireAges 18–65 - NCT07591584Recruiting
Digestive Enzyme Blend for Bloating and Gas Relief
This study tests whether a daily digestive enzyme supplement designed to break down certain hard-to-digest foods can reduce bloating and belly pain. You'll use a smartphone app to track your symptoms over several weeks to see if the enzyme helps.
Los Angeles, CaliforniaAges 18 years+ - NCT06721624Recruiting
Natural approaches for IBS: a research study
This study observes how naturopathic treatments help people with Irritable Bowel Syndrome (IBS) or IBS-like symptoms. It aims to understand what works in real-world care.
Portland, OregonAges 18 years+ - NCT07584473Recruiting
Testing for Non-Celiac Wheat Sensitivity in Celiac Disease Relatives
This study investigates whether relatives of celiac disease patients who have digestive symptoms and other health concerns might have non-celiac wheat sensitivity or irritable bowel syndrome. Researchers will perform a small intestinal biopsy and dietary testing to understand the connection between wheat sensitivity and symptoms in this family group.
Palermo, PAAges 18 years+ - NCT06749613Recruiting
Digestive enzymes for IBS after diet response
This trial tests whether a digestive enzyme supplement can help people with irritable bowel syndrome (IBS) whose symptoms returned after they previously improved on a special low-FODMAP Mediterranean diet.
Chaïdári, AthensAges 18–65 - NCT07494968Recruiting
Finding ways to track diet compliance in IBS patients
This study looks for signs in your body—like breath and blood tests—that can show how well you are following a special diet for IBS. It aims to find better ways to track diet compliance, which could help make dietary treatments more effective.
Ann Arbor, MichiganAges 18–65 - NCT07424898Enrolling by invitation
Lactose Intolerance and Gut Health Study
This study looks at how lactose intolerance is linked to gut health. It is for adults with ongoing digestive issues like bloating, pain, or diarrhea, to see if their gut lining may be more sensitive.
IstanbulAges 18–70 - NCT07360938Recruiting
How inflammation affects drug processing
This study looks at how inflammation from conditions like diabetes, IBD, or kidney disease affects the way drugs work in the body. It may help improve dosing and safety for patients with these conditions.
Indianapolis, IndianaAges 12–99 - NCT07309601Recruiting
Sucrase-isomaltase genes and meal study for IBS
This study looks at how people with irritable bowel syndrome (IBS) handle meals based on their genes for an enzyme that breaks down sugar and starch. It may help explain why some people benefit from a starch- and sugar-reduced diet.
Malmö, Skåne CountyAges 18–70 - NCT07283341Recruiting
Diet and Gut Movement in Irritable Bowel Syndrome
This study looks at how diet affects gut movement in children with irritable bowel syndrome (IBS). It may help find better ways to manage IBS symptoms.
Philadelphia, PennsylvaniaAges 8–18
Hear when a new Irritable Bowel Syndrome - Diarrhoea trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for irritable bowel syndrome - diarrhoea?
- Yes. Clin2 currently lists 104 recruiting irritable bowel syndrome - diarrhoea studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a irritable bowel syndrome - diarrhoea trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a irritable bowel syndrome - diarrhoea trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.