Clinical trials
Irritable Bowel Syndrome clinical trials
Below are recruiting irritable bowel syndrome clinical trials, each written for real people, not researchers. We’re tracking 110 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06749613Recruiting
Digestive enzymes for IBS after diet response
This trial tests whether a digestive enzyme supplement can help people with irritable bowel syndrome (IBS) whose symptoms returned after they previously improved on a special low-FODMAP Mediterranean diet.
Chaïdári, AthensAges 18–65 - NCT07494968Recruiting
Finding ways to track diet compliance in IBS patients
This study looks for signs in your body—like breath and blood tests—that can show how well you are following a special diet for IBS. It aims to find better ways to track diet compliance, which could help make dietary treatments more effective.
Ann Arbor, MichiganAges 18–65 - NCT07424898Enrolling by invitation
Lactose Intolerance and Gut Health Study
This study looks at how lactose intolerance is linked to gut health. It is for adults with ongoing digestive issues like bloating, pain, or diarrhea, to see if their gut lining may be more sensitive.
IstanbulAges 18–70 - NCT07360938Recruiting
How inflammation affects drug processing
This study looks at how inflammation from conditions like diabetes, IBD, or kidney disease affects the way drugs work in the body. It may help improve dosing and safety for patients with these conditions.
Indianapolis, IndianaAges 12–99 - NCT07309601Recruiting
Sucrase-isomaltase genes and meal study for IBS
This study looks at how people with irritable bowel syndrome (IBS) handle meals based on their genes for an enzyme that breaks down sugar and starch. It may help explain why some people benefit from a starch- and sugar-reduced diet.
Malmö, Skåne CountyAges 18–70 - NCT07283341Recruiting
Diet and Gut Movement in Irritable Bowel Syndrome
This study looks at how diet affects gut movement in children with irritable bowel syndrome (IBS). It may help find better ways to manage IBS symptoms.
Philadelphia, PennsylvaniaAges 8–18 - NCT07261826Recruiting
Long-term effects of fecal microbiota transplant
This study looks at how well fecal microbiota transplantation (FMT) works over time and checks its safety. If you have received at least one FMT for a qualifying condition, you may be able to participate.
Shanghai, Shanghai MunicipalityAges 3 years+ - NCT06247046RecruitingPhase 3
Probiotic powder for IBS-D (SK08) trial
This study tests a new probiotic powder (SK08) to see if it reduces belly pain and diarrhea in people with IBS-D (irritable bowel syndrome with diarrhea). It lasts several months and involves taking the study powder twice a day.
Wuxi, JiangsuAges 18–70 - NCT07235228Recruiting
Synbiotic supplement for irritable bowel syndrome
This trial tests whether a synbiotic (a mix of probiotics and prebiotics) called Vivatlac can improve gut health in people with moderate to severe irritable bowel syndrome (IBS). If you have IBS and are not already taking probiotics or antibiotics, you may be able to join.
JarocinAges 18–65 - NCT07222943Recruiting
Guided Imagery App for Kids with Stomach Pain
This study tests a mobile app that uses guided imagery (a relaxation technique using your imagination) to help children ages 7–12 with stomach pain disorders. The goal is to see if the app is easy to use and helpful for managing pain.
Austin, TexasAges 7–12 - NCT06912828Recruiting
Genes and diet for IBS
This trial is studying whether your genes can predict how well a special diet will help your IBS symptoms. If you have moderate to severe IBS and no other diet-related conditions, you may be able to take part.
AthensAges 18–65 - NCT07094035Recruiting
Green tea and probiotics for constipation-predominant IBS
This study tests whether a supplement containing green tea extract and probiotics can improve bowel function in people with irritable bowel syndrome (IBS) that mainly causes constipation. If you have chronic constipation and abdominal pain, this could help.
NaplesAges 18–70 - NCT07000227Recruiting
Low FODMAP diet study for IBS or functional dyspepsia
This study looks at how a low FODMAP diet affects people with irritable bowel syndrome (IBS) or functional dyspepsia (FD). It aims to understand why this diet helps some patients and may offer a way to manage your symptoms.
Kuala Lumpur, Kuala LumpurAges 18 years+ - NCT06923800Recruiting
Exercise and Diet Advice for Fibromyalgia and IBS
This study tests whether combining exercise with dietary advice can help people who have both fibromyalgia and irritable bowel syndrome (IBS). It aims to see if this approach improves symptoms and quality of life.
Castellana Grotte, BariAges 30–65 - NCT06866106Recruiting
Well-being in IBS: A phone program for strengths and happiness
This study tests a program that helps people with IBS focus on their strengths and happiness through phone sessions. It aims to see if this approach can improve well-being and manage IBS symptoms.
Boston, MassachusettsAges 18 years+ - NCT06847360Recruiting
Home-based ear stimulation for IBS pain
This trial tests a gentle, non-invasive ear stimulation device (taVNS) used at home to reduce pain from Irritable Bowel Syndrome (IBS). It might help if you have moderate pain most days.
New Haven, ConnecticutAges 18–29 - NCT06727422RecruitingPhase 2
Rifaximin plus NAC for IBS with diarrhea
This trial tests whether a combination of two medications—rifaximin (a gut antibiotic) and NAC (a supplement that helps break down mucus)—can reduce belly pain and diarrhea in people with IBS whose symptoms are not well controlled. It may be an option if other treatments haven't worked well enough.
Los Angeles, CaliforniaAges 18 years+ - NCT06684470RecruitingEarly Phase 1
Combining a low-FODMAP diet with medication for IBS-D
This trial tests if a special diet (low-FODMAP) combined with a medication (mirtazapine) can improve IBS with diarrhea symptoms. It is for adults who have not tried these treatments before.
Jacksonville, FloridaAges 18–70 - NCT06639984RecruitingPhase 2
Psyllium for kids with IBS
This study tests if psyllium, a fiber supplement, helps reduce belly pain and other symptoms in children with irritable bowel syndrome (IBS). It may be an option if standard treatments haven't worked well.
Durham, North CarolinaAges 12–17 - NCT06583395Enrolling by invitation
Meditation retreat study with fitness tracker
This trial studies people attending a 7-day meditation retreat to see how meditation affects well-being. You will wear a fitness tracker and answer surveys.
Palm Desert, CaliforniaAges 21 years+ - NCT06369753Recruiting
Study on visible belly swelling after meals
This study looks at people whose belly visibly swells after eating. The goal is to understand this condition and track symptoms over time.
Los Angeles, CaliforniaAges 18–80 - NCT06288672Recruiting
Skin patch test for food allergies in IBS
This study tests whether a skin patch can help identify food allergies in people with irritable bowel syndrome (IBS) whose symptoms are not well controlled. It involves avoiding certain foods and using patches on your back to see if you react.
North Wales, PennsylvaniaAges 18 years+ - NCT05972291Recruiting
Study gut changes in Gulf War illness with chronic stomach symptoms
This study looks at what’s driving Gulf War illness, focusing on gut symptoms like belly pain, diarrhea, and bloating. It may help researchers test approaches aimed at gut barrier function in eligible veterans.
Memphis, TennesseeAges 18–65 - NCT05905926Enrolling by invitationPhase 3
Tenapanor safety study for teens with constipation-predominant IBS
This trial checks the safety of tenapanor in children and teens (ages 6 to under 18) with IBS-C. It is only for people who finished a previous related study and agreed to continue follow-up.
Foley, AlabamaAges 6–18
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Common questions
- Are there clinical trials for irritable bowel syndrome?
- Yes. Clin2 currently lists 110 recruiting irritable bowel syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a irritable bowel syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a irritable bowel syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.