Clinical trials
Knee Arthritis Osteoarthritis clinical trials
Below are recruiting knee arthritis osteoarthritis clinical trials, each written for real people, not researchers. We’re tracking 211 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06833749RecruitingPhase 2
Testing KBP-336 for knee osteoarthritis with obesity
This study tests an experimental medicine called KBP-336 for people with both obesity and knee osteoarthritis who still have significant knee pain despite standard treatments. It aims to see if KBP-336 can reduce pain and improve function.
BrnoAges 45 years+ - NCT05507099RecruitingPhase 2
Stem cell injections for knee or hip osteoarthritis pain
This Phase 2 study tests whether stem cell injections can reduce pain and improve symptoms in people with knee or hip osteoarthritis. You may be considered if you have moderate-to-severe pain despite trying standard treatments.
Brampton, OntarioAges 18–95 - NCT07367126Recruiting
Nerve pain in knee osteoarthritis: Pain and function study
This study looks at nerve-related pain in people with knee osteoarthritis and how it affects their pain level and daily function. It may help understand if nerve pain is a key factor in your knee OA symptoms.
IstanbulAges 40–70 - NCT06058169Recruiting
Home vibration therapy for arthritis knee pain
This study tests if doing whole-body vibration exercises at home can help reduce knee pain from arthritis. You stand on a gently vibrating platform for short periods over several weeks.
Augusta, GeorgiaAges 40–75 - NCT06637709Recruiting
Pain after osteoarthritis treatment: a 24-month study
This study looks at why some people still have pain after knee surgery or other treatments for osteoarthritis. It tests a marker in the blood to see if it relates to ongoing pain. You would be followed for 24 months.
Roma, RomaAges 18–99 - NCT07695168Recruiting
Digital course and rehab for knee osteoarthritis
This study tests whether a digital program with special sensors and a digital twin can help reduce knee pain and improve mobility in older adults with knee osteoarthritis. It also includes healthy adults for comparison.
TaipeiAges 20–80 - NCT06701474Recruiting
Knee replacement recovery: comparing body composition groups
This study looks at how well people recover after total knee replacement, comparing those with different body composition levels. The goal is to see if a measure called 'phase angle' affects recovery of strength and function.
Yongin-si, Gyeonggi-doAges 55 years+ - NCT05599776Recruiting
Smart ring-guided rehab after knee replacement surgery
This study tests whether using a smart ring along with physical therapy after knee replacement helps people recover better. It mainly looks at people’s rehab progress in the weeks after surgery.
Tampere, PirkanmaaAges 18–70 - NCT07763158Recruiting
Treatment for severe knee pain using artery embolization
This study tests a procedure that blocks tiny arteries in the knee to reduce pain from severe arthritis. It is for people who cannot have knee replacement surgery because of other health issues.
Jeddah, Mecca RegionAges 18 years+ - NCT05806021RecruitingPhase 4
Tested different cortisone doses for knee osteoarthritis pain
This trial compares different doses of injected cortisone (triamcinolone) directly into the knee to see which dose helps knee osteoarthritis pain most. You may be enrolled in a group receiving a 5 mg, 10 mg, or 40 mg dose if you meet the study’s knee and health requirements.
Montreal, QuebecAges 50 years+ - NCT07316933Recruiting
Exercise with light blood flow restriction before knee replacement
This trial tests if a specific type of exercise, done with a cuff that lightly restricts blood flow to your leg, can help you get stronger and recover better while you wait for knee replacement surgery. The blood flow restriction is carefully controlled and adjusted during exercise, which may make the workout more effective.
Valencia, ValenciaAges 50–85 - NCT07006883Recruiting
Yoga program for knee osteoarthritis
This trial tests whether a yoga program can improve daily function in people with knee osteoarthritis. It may help reduce pain and stiffness while improving mobility.
São PauloAges 40–80 - NCT06073106Recruiting
Frailty prevention study for older Asian adults
This trial tests a program to prevent frailty in people aged 50 and older of Asian descent who have recently been diagnosed with a stroke, traumatic brain injury, knee osteoarthritis, or breast cancer. The goal is to help you stay strong and healthy as you recover.
Singapore, SingaporeAges 50 years+ - NCT05992038Recruiting
Bone putty as gap filler in knee realignment surgery
This trial tests a new bone putty used to fill the small gap created during realignment surgery for knee osteoarthritis. It aims to see if the putty helps the bone heal better and reduces pain.
Utrecht, UtrechtAges 18 years+ - NCT02993029Recruiting
Fluoride scan–guided treatment for painful knee arthritis
This trial studies a targeted treatment using a fluoride-related injection to help reduce pain from knee osteoarthritis. To join, you need a painful osteoarthritis knee and a specific bone-scan finding (SUV above 10) on an imaging test.
Shanghai, Shanghai MunicipalityAges 40 years+ - NCT06311513RecruitingPhase 4
Concentrated bone marrow injection during repeat ACL surgery
This study tests whether adding a concentrated bone marrow injection during repeat ACL surgery helps healing and recovery better than surgery alone. If you have had a previous ACL reconstruction that failed, you may be eligible.
Atlanta, GeorgiaAges 18–55 - NCT07845695Recruiting
Music before joint replacement surgery to ease anxiety
This study tests whether listening to music just before hip or knee replacement surgery can help reduce anxiety. If you are having surgery for arthritis and are comfortable listening to music, you may be able to join.
New York, New YorkAges 18 years+ - NCT05985785Recruiting
Bone Marrow vs Steroid Injection for Knee Arthritis
This study compares two different knee injections—one using your own concentrated bone marrow cells (BMAC) and the other using a steroid (cortisone)—to see which works better for long-term knee pain from osteoarthritis.
Chicago, IllinoisAges 18–70 - NCT07023185Recruiting
Cold and compression after knee replacement
This study will test if adding cold and compression therapy after knee replacement surgery can help with pain, swelling, and recovery. You may qualify if you are 50 or older and having a knee replacement with a specific surgeon.
New Orleans, LouisianaAges 50 years+
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Common questions
- Are there clinical trials for knee arthritis osteoarthritis?
- Yes. Clin2 currently lists 211 recruiting knee arthritis osteoarthritis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a knee arthritis osteoarthritis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a knee arthritis osteoarthritis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.