Clinical trials
Ligament Injury clinical trials
Below are recruiting ligament injury clinical trials, each written for real people, not researchers. We’re tracking 89 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07411625Recruiting
Pre-surgery exercise program for ACL injury patients
This trial tests whether doing special exercises before ACL surgery (called prehabilitation) helps you recover better after the operation. It's for people who have a first-time ACL tear and are scheduled for reconstruction surgery using a tendon from their own body.
NantesAges 18 years+ - NCT06571240Recruiting
Turkish Activity Score Tool for ACL Surgery Patients
This study checks if a new Turkish version of an activity score (Tegner) is valid and reliable for people having ACL surgery. If you are having your first ACL repair and speak Turkish, you may be able to take part.
AnkaraAges 18 years+ - NCT06571227Recruiting
Understanding knee scores after ACL surgery
This study aims to find what a 'normal' knee score (Lysholm score) means for people after ACL surgery. It will help doctors know if your recovery is on track.
AnkaraAges 18 years+ - NCT04408885Recruiting
Rehab program for a torn ACL ligament
This study looks at a rehabilitation-focused treatment plan after an ACL (an important knee ligament) tear. It may help you by testing the best rehab approach for improving knee function and stability.
Aarhus NAges 18–50 - NCT05073263Recruiting
Full versus partial weight bearing after FCL ligament repair
This study compares two rehab plans: doing full weight bearing versus partial weight bearing during the first 6 weeks after fibular collateral ligament (FCL) reconstruction. It may help figure out which approach is safer and better for healing and recovery.
Edina, MinnesotaAges 14–59 - NCT05073276Recruiting
Controlled weight-bearing after PCL or MCL knee ligament repair
This trial tests a specific, step-by-step approach to how much weight you put on your healing knee after surgery for certain ligament injuries (like PCL and/or MCL, and some combined cases). It may help you heal safely and recover function without putting too much strain on the repair.
Edina, MinnesotaAges 14–59 - NCT05747079Recruiting
Early versus delayed surgery after a new ACL tear
This study compares immediate surgery versus waiting a short time for people with a new ACL injury. It aims to see which timing leads to better recovery and knee function.
LeuvenAges 16 years+ - NCT06559215RecruitingPhase 2
Pain management with Exparel after knee surgery in teens
This trial is testing a long-acting numbing medicine called Exparel to see how well it controls pain after a specific knee surgery (MPFL reconstruction) in teens and young adults. It may help reduce the need for strong painkillers after the operation.
Frisco, TexasAges 13–21 - NCT06235736Recruiting
Do ACL tears cause weakness in the soleus muscle?
This study looks at whether people with ACL tears have weakness in a specific calf muscle called the soleus. If you have an ACL tear, you will do strength tests to compare with healthy individuals.
LiverpoolAges 18–55 - NCT05391672Recruiting
Study for early surgery after a partial ACL tear
This trial looks at treatment options for people with a partial ACL ligament tear in the knee, including both recent and long-standing injuries. It may help to clarify the best early approach for healing and knee function, especially when there are no other ligament injuries.
AsyutAges 15–50 - NCT04572256RecruitingEarly Phase 1
Montelukast after ACL surgery to protect knee cartilage
This early trial tests whether montelukast, a tablet used for allergies, can help protect knee cartilage after ACL surgery. It is specifically for people who have a meniscus injury along with their ACL tear.
Lexington, KentuckyAges 25–50 - NCT06206200Recruiting
Thinking and moving after ACL surgery
This study looks at how doing a thinking task at the same time as a walking or balance task affects recovery in people who have had ACL reconstruction surgery. It may help you understand what to expect during later stages of rehab.
Roeselare, West-VlaanderenAges 18–40 - NCT06507241Recruiting
Knee meniscus root tear repair using ligament suture
This trial tests a surgical technique to fix a certain type of meniscus tear (called a root tear) by stitching it to the knee's posterior cruciate ligament. The goal is to see if this approach helps patients recover better.
BolognaAges 18–50 - NCT06770153Recruiting
A trial comparing two knee replacement balancing techniques
This study compares a special tensioning tool to the standard method for balancing a new knee joint during total knee replacement. It aims to see which technique provides better outcomes.
BolognaAges 50–85 - NCT02918734Recruiting
ACL surgery: compare two ways to secure the tendon graft
This study looks at two surgical methods to attach the tendon graft during ACL reconstruction, using either an Endobutton or metal interference screws. It may help patients by improving how securely the graft is fixed and how well recovery goes.
TrondheimAges 18–55 - NCT07097077Recruiting
Brain changes after ACL surgery with special training
This study uses brain scans (fMRI) to see how a special type of movement training affects the brain after ACL surgery. If you've had an ACL repair and are active in sports, you may be eligible.
Bologna, BolognaAges 18–30 - NCT07049484Recruiting
ACL surgery with extra ligament reinforcement study
This study looks at how well an ACL reconstruction works when it also includes a second procedure (LET) to give extra support to the knee. It may help people who need this specific type of surgery have better stability and movement afterward.
BolognaAges 18–50
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Common questions
- Are there clinical trials for ligament injury?
- Yes. Clin2 currently lists 89 recruiting ligament injury studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ligament injury trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ligament injury trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.