Clinical trials
Liver Transplantation clinical trials
Below are recruiting liver transplantation clinical trials, each written for real people, not researchers. We’re tracking 200 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06874296Recruiting
Testing machine perfusion for declined livers to shorten transplant wait time
This trial tests whether using a machine to keep donated livers healthy (normothermic machine perfusion) can allow more people to receive a transplant sooner. It is for patients who are already on the waiting list for a liver and have a moderately severe MELD score (25 or less).
Hamburg, Free and Hanseatic City of HamburgAges 18 years+ - NCT07123740Recruiting
Pain relief after liver donor surgery: two methods compared
This study compares two ways to control pain after surgery for living liver donors. It tests if one method works better than the other, which could help you recover more comfortably.
Altındağ, AnkaraAges 18–65 - NCT01644903Recruiting
Checking biomarkers after a liver transplant
This study follows people who are getting a liver transplant (including repeat transplants) to monitor changes in their body using test results. It may help doctors understand how patients are doing after transplant and improve care over time.
Chicago, IllinoisAges 18 years+ - NCT07607873Recruiting
Transplant vs surgery after chemo for liver-only colorectal cancer
This trial compares liver transplant versus liver surgery for people whose colorectal cancer has spread only to the liver and cannot be removed initially. You would first receive chemotherapy to shrink the tumors, and if they become removable, you may be randomly assigned to have a liver transplant or standard liver surgery.
MilanAges 18 years+ - NCT06341543Recruiting
CMV blood test to guide treatment after organ transplant
This study uses a blood test (QuantiFERON-CMV) to help decide whether people with a silent (no symptoms) CMV infection after a solid organ transplant need treatment. If you have a low-to-moderate level of CMV in your blood without fever or organ issues, this trial may help your doctor choose the safest approach.
Grenoble, MarylandAges 18 years+ - NCT02864485Recruiting
Living donor liver transplant for colorectal cancer spread to the liver
This trial looks at whether a living-donor liver transplant can help people with colorectal cancer that has spread to the liver but cannot be surgically removed. It focuses on people whose cancer has not worsened on prior chemotherapy and who are medically able to undergo a major liver surgery.
Toronto, OntarioAges 18–68 - NCT05248581Recruiting
Living donor liver transplant for unresectable colon cancer spread
This trial looks at using a living donor liver transplant for people whose colon or rectal cancer has spread to the liver in a way that can’t be removed with standard surgery. It may help if you might otherwise have limited options because your liver surgery would be too risky.
Rochester, New YorkAges 18 years+ - NCT06048445Recruiting
Preventing bile duct issues after children's liver transplant
This trial tests placing a temporary drainage stent during liver transplant surgery in children to see if it helps prevent bile duct complications. It might improve recovery for young transplant recipients.
Hangzhou, ZhejiangAges 1–6 - NCT04595864RecruitingPhase 3
Chemotherapy into the liver before transplant for liver cancer
This trial tests whether giving chemotherapy directly into the liver blood supply before a liver transplant can help people with liver cancer that is beyond standard transplant criteria. It may help lower cancer risk around the time of transplant while keeping people healthy enough to receive the transplant.
Nanjing, JiangsuAges 18–75 - NCT04613921Recruiting
Liver transplant study for severe worsening liver failure
This study looks at when liver transplant is offered and what outcomes happen in people with cirrhosis who have severe “acute-on-chronic” worsening. It may help doctors decide which patients benefit most from transplant and improve care after listing or not listing.
Los Angeles, CaliforniaAges 18–80 - NCT06060392Recruiting
Semaglutide pill for liver fat in transplant patients with diabetes
This study tests if an oral semaglutide pill can reduce liver fat and improve body composition in people who have had a liver transplant and have diabetes. It may help manage weight and blood sugar after transplant.
Gurgaon, HaryanaAges 30 years+ - NCT02784119Recruiting
Temporary bypass during liver transplant to help extended-donor livers
This trial studies a temporary surgical bypass during liver transplantation to improve how well the new liver works, especially when the donor liver is “extended criteria.” It may help patients whose transplant plan includes a higher-risk donor liver by testing whether the bypass better protects the graft.
BordeauxAges 18 years+ - NCT05185245Recruiting
Liver transplant for colorectal cancer spread to the liver
This study looks at whether a liver transplant can help people whose colorectal cancer has spread to the liver but cannot be removed by surgery. It also checks whether certain cancer features, treatment history, and blood/health status make transplant safer or more effective.
BolognaAges 18–73 - NCT05398380Recruiting
Liver transplant for colorectal liver cancer that can’t be removed
This trial studies liver transplantation for certain people with colorectal cancer that has spread only to the liver and cannot be removed with surgery. It aims to improve outcomes for carefully selected patients whose cancer is controlled on chemotherapy and who meet specific safety and scan requirements.
Barcelona, BarcelonaAges 18–70 - NCT05106322Recruiting
Using a hand scanner to check fat buildup in liver grafts
This study tests whether an on-site, hand-held scanner during surgery can estimate fat-related liver changes in donated liver tissue. It may help surgeons better assess the quality of liver grafts while the transplant is happening.
VillejuifAges 18 years+ - NCT07102550RecruitingPhase 2
Amniotic tissue for bile duct repair in living donor liver transplant
This trial tests whether using amniotic tissue during bile duct connection surgery can improve outcomes for people receiving a liver transplant from a living donor.
Cleveland, OhioAges 18 years+ - NCT07703735Enrolling by invitation
Survival after ABO-mismatch living donor liver transplant for liver cancer
This trial looks at how well patients with liver cancer do after receiving a living donor liver transplant that is not the same blood type. It compares survival and cancer return for these patients.
Ages 18 years+ - NCT06905054RecruitingPhase 2
Preventing PSC recurrence after liver transplant
This trial tests whether fenofibrate can prevent primary sclerosing cholangitis (PSC) from coming back after a liver transplant. It is for adults who had a liver transplant for PSC between 1 and 7 years ago and have certain risk factors.
Scottsdale, ArizonaAges 18–75 - NCT06344442RecruitingPhase 3
Low-dose vasopressin for kidney protection after liver transplant
This trial tests whether giving a low dose of a hormone called vasopressin after a liver transplant can help prevent kidney injury. It's for adults scheduled for a planned liver transplant.
ParisAges 18 years+ - NCT03310905Recruiting
Abdominal wall transplant for people needing multi-organ transplant
This study evaluates an abdominal wall transplant (replacing the front belly/tissue) done along with another organ transplant. It may help people who need a specialized transplant approach, but it’s only for certain candidates at Duke who meet strict safety and cancer, pregnancy, and anesthesia requirements.
Durham, North CarolinaAges 18–65 - NCT07574398Recruiting
Growth and Development Study After Infant Liver Transplant
This study tracks how babies grow and develop after receiving a liver transplant. Researchers want to understand how transplantation affects children's physical growth and overall development in early infancy.
Shanghai, Shanghai MunicipalityAges Up to 1 year - NCT06280950RecruitingPhase 2
Reducing immune-suppressing drugs after liver transplant with everolimus
This study tests if adding everolimus can allow liver transplant recipients to safely reduce their usual immune-suppressing medicines. It aims to protect kidney function while preventing organ rejection.
Phoenix, ArizonaAges 18 years+ - NCT07288281Recruiting
Preoperative Clear Fluid Fasting in Liver Transplant
This trial looks at how long before surgery patients waiting for a liver transplant can drink clear fluids, like water. The goal is to find a safer or more comfortable fasting time.
Warsaw, WarszawaAges 18 years+ - NCT05326399Recruiting
Kidney biopsies after liver transplant for new kidney problems
This trial studies kidney biopsies in people who had a liver transplant and then developed new signs of kidney damage. The goal is to better understand what’s causing the problem and how to guide next steps.
ShanghaiAges 18–75
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Common questions
- Are there clinical trials for liver transplantation?
- Yes. Clin2 currently lists 200 recruiting liver transplantation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a liver transplantation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a liver transplantation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.