Clinical trials
Liver Transplantation clinical trials
Below are recruiting liver transplantation clinical trials, each written for real people, not researchers. We’re tracking 194 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03310905Recruiting
Abdominal wall transplant for people needing multi-organ transplant
This study evaluates an abdominal wall transplant (replacing the front belly/tissue) done along with another organ transplant. It may help people who need a specialized transplant approach, but it’s only for certain candidates at Duke who meet strict safety and cancer, pregnancy, and anesthesia requirements.
Durham, North CarolinaAges 18–65 - NCT06756009Recruiting
Eye scans to check liver disease and transplant outlook
This study uses advanced eye scans to see if your eyes can give clues about your chronic liver disease and how well you might do after a liver transplant. If you have advanced liver disease or cirrhosis, and are maybe waiting for a transplant, you may join.
Guangzhou, GuangdongAges 18 years+ - NCT06717542Recruiting
Liver tissue analysis to predict transplant success
This study looks at liver tissue before transplantation to find ways to predict how well the transplant will work. It involves a special treatment called HOPE to help preserve the liver.
BolognaAges 18 years+ - NCT06698146Recruiting
Liver transplant for colorectal cancer that spread to the liver
This trial tests a special approach for colorectal cancer that has spread to the liver: first removing the liver tumor, then doing a partial liver transplant, and later removing more liver tissue. The goal is to see if this can help people who otherwise have limited options.
Chicago, IllinoisAges 18 years+ - NCT06890234Enrolling by invitation
Monitoring liver grafts with a tiny probe during transplant
This study uses a tiny probe placed in the new liver during transplant surgery to monitor its health in real time. It may help doctors detect problems early and improve recovery after transplant.
Ljubljana, SloveniaAges 18–65 - NCT03193151Recruiting
Microarray testing to guide care after liver transplant
This study looks at how special lab tests from tiny tissue samples (microarrays) could help guide diagnosis and treatment in people who receive a liver transplant. It may help doctors better understand what’s going on and choose care more accurately.
San Francisco, CaliforniaAges 18 years+ - NCT03494946Recruiting
Liver transplant vs chemotherapy for colon cancer liver spread
This trial compares liver transplantation to standard chemotherapy for people with colon or rectal cancer that has spread to the liver but cannot be removed surgically. It looks at whether transplant can help patients live longer or better than chemotherapy in the right patients.
OsloAges 18 years+ - NCT03488953Recruiting
Two-step liver surgery using a living donor transplant
This study looks at a specialized liver transplant approach using a living donor, for people with colorectal cancer that has spread only to the liver and cannot be removed by standard surgery. It’s meant for cases where chemotherapy has helped stop or shrink the tumors, to improve the chance of successful treatment.
JenaAges 18 years+ - NCT02215889RecruitingPhase 1/Phase 2
Partial liver transplant for colon or rectal cancer spread to liver
This trial tests whether transplanting part of the liver can help people with colon or rectal cancer that has spread to the liver but cannot be removed with surgery. It also aims to make sure the cancer is limited mainly to the liver and that you are healthy enough for major treatment.
OsloAges 18 years+ - NCT06781502Recruiting
Liver Disease and Transplant Study
This study is creating a database of people with severe liver problems or who have had a liver transplant. The goal is to learn more about these conditions and improve care.
Bologna, BolognaAges 18 years+ - NCT06254248RecruitingPhase 2
Safety of two cancer drugs after liver transplant
This trial tests a combination of two drugs (atezolizumab and bevacizumab) for people whose liver cancer has returned after a liver transplant and cannot be treated with surgery or other local procedures. The goal is to see if this treatment is safe for liver transplant recipients.
ClichyAges 18–90 - NCT05170971Recruiting
Fecal transplant trial for worsening liver failure
This trial studies fecal microbiota transplantation (a transfer of healthy gut bacteria from a donor) to help people with worsening liver failure. It may help by changing gut bacteria, which can affect complications like confusion, fluid buildup, infections, and kidney problems.
Ningbo, ZhejiangAges 18–65 - NCT04932577RecruitingPhase 2/Phase 3
Fecal transplant to treat complications of liver cirrhosis
This trial studies whether transferring healthy gut bacteria (from a donor sample) can improve outcomes for people with liver cirrhosis who have worsening complications. It may help by changing the gut microbiome, which can influence inflammation and liver health.
AarhusAges 18–75 - NCT05866783Recruiting
Blood test to predict cancer coming back after liver transplant
This study uses a blood test (looking at sugars in the blood) to help predict whether liver cancer will come back after a liver transplant. It may help doctors monitor you more accurately and earlier if cancer returns.
GhentAges 18 years+ - NCT07247877Enrolling by invitation
Study of small liver grafts for portal hypertension treatment
This trial explores using smaller liver grafts in a partial transplant to treat portal hypertension, which may help patients avoid full transplant risks. It compares this approach to standard liver transplant.
Ages 14 years+ - NCT04204850RecruitingPhase 2
Cabozantinib for liver cancer that returns after liver transplant
This trial studies cabozantinib, a cancer medicine, for liver cancer that has come back after a liver transplant. It’s for people whose cancer can’t be cured with more surgery or local procedures, to see if the treatment can help control the disease.
Toronto, OntarioAges 18 years+ - NCT05940857Recruiting
Liver transplant registry using a special machine before surgery
This is a registry that collects information about liver transplant recipients. It helps researchers understand outcomes related to a specific liver “perfusion” process used around the time of transplant.
Birmingham, AlabamaAges Any age - NCT06716541Recruiting
Biodegradable stent for bile duct narrowing after liver transplant
This study is testing a special temporary stent that breaks down over time to help open a narrowed bile duct after a liver transplant. It may help avoid long-term plastic stents or additional surgery.
PragueAges 18 years+ - NCT06838702Recruiting
Liver transplant bone health study
This study collects information from people getting a liver transplant. It looks at bone health and mineral levels in the body to better understand how they change after transplant.
Bologna, BolognaAges 18 years+ - NCT06140134Recruiting
Liver transplant for bile duct cancer that hasn't spread
This study tests if a liver transplant can help people with a type of bile duct cancer that can't be removed with surgery. You may join if the cancer has stayed stable or shrunk for at least 6 months with treatment.
Newark, New JerseyAges 18–89 - NCT04195503Enrolling by invitation
Liver transplant for stable advanced bile duct cancer
This trial looks at liver transplant for people with advanced intrahepatic cholangiocarcinoma (a bile duct cancer inside the liver) when the cancer is not safely removable and stays controlled. It may help some patients live longer and with better quality of life by replacing the diseased liver—if strict safety and disease-stability requirements are met.
Toronto, OntarioAges 18 years+ - NCT06725121RecruitingPhase 1/Phase 2
Radiation and immunotherapy for advanced liver cancer before transplant
This trial tests combining radiation therapy with immunotherapy (AtezoBev) before a liver transplant for advanced liver cancer. The goal is to see if this approach can shrink tumors and make transplant possible for more people.
London, OntarioAges 18–70 - NCT04499833Recruiting
Test an AI score to guide liver transplant decisions
This study looks at a prediction tool that estimates outcomes for people with liver cancer and cirrhosis, to help decide whether a liver transplant is a good option. It may help doctors choose the right timing and patients who could benefit most from transplantation.
LisbonAges 18–70 - NCT05089604RecruitingPhase 4
Compare two tacrolimus forms to reduce tremors after liver transplant
This study compares immediate-release versus extended-release tacrolimus (an anti-rejection medicine) to see if one form causes fewer tremors after a first liver transplant. It may help you and your care team choose the best form if tremors are a problem while your body adjusts after transplant.
Vancouver, British ColumbiaAges 18 years+
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Common questions
- Are there clinical trials for liver transplantation?
- Yes. Clin2 currently lists 194 recruiting liver transplantation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a liver transplantation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a liver transplantation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.