Clinical trials
Liver clinical trials
Below are recruiting liver clinical trials, each written for real people, not researchers. We’re tracking 1,219 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06342440Recruiting
Early detection of colon cancer and advanced polyps
This study aims to find colorectal cancer and advanced polyps (adenomas) earlier by looking at blood samples. Researchers hope a simple blood test might one day help detect colon cancer before it spreads.
Monrovia, CaliforniaAges 18 years+ - NCT06318169RecruitingPhase 3
Testing pegozafermin for MASH and liver fibrosis
This trial tests an experimental drug called pegozafermin to see if it can help people with MASH (a fatty liver disease) and liver scarring (fibrosis). It's for people who have moderate-to-advanced scarring but not cirrhosis, and who have not had other serious liver conditions or poorly controlled diabetes.
Birmingham, AlabamaAges 18–80 - NCT06327308RecruitingPhase 1
MRI study for heart health in liver transplant candidates
This study uses a special heart MRI to check for a heart condition called cirrhotic cardiomyopathy in people waiting for a liver transplant. The results may help doctors better understand and treat heart problems in patients with cirrhosis.
BesançonAges 18–70 - NCT06335771Recruiting
Study on fat metabolism in obesity and diabetes
This study looks at how fat is processed in the body for people with different health conditions, including obesity and type 2 diabetes. It aims to find new ways to improve treatment by understanding these differences.
Columbia, MissouriAges 18–70 - NCT06324396RecruitingPhase 1
Improving drug dosing for single ventricle patients with liver disease
This trial studies how the drugs sildenafil and pravastatin work in people with a single ventricle heart condition who have had the Fontan surgery and may have related liver problems. The goal is to find the best doses based on liver function.
Kansas City, MissouriAges 8 years+ - NCT06307964Recruiting
Gut bacteria in alcoholic hepatitis
This trial is looking at bacteria inside the liver of people with alcoholic hepatitis. It may help understand how these bacteria affect the disease and lead to better treatments.
LyonAges 18 years+ - NCT06316154Recruiting
Liver cyst wall study during echinococcosis surgery
This study looks at parts of the liver cyst wall during surgery for echinococcosis. It aims to learn more about the infection to help future treatments.
Tashkent, UzbekistanAges 18–80 - NCT03267615Recruiting
Study in advanced liver scarring using pressure and stiffness tests
This study looks at people over 18 who have advanced, long-term liver scarring. It uses specialized measurements of liver stiffness and pressure to confirm eligibility and may help doctors better understand this condition.
ViennaAges 18–100 - NCT06291675Recruiting
Hormone therapy's effect on heart and organ fat
This study uses MRI scans to see how gender-affirming hormone therapy affects heart muscle, heart function, and fat in the heart, liver, and pancreas. It may help us understand long-term health effects of hormone therapy.
Vienna, State of ViennaAges 18 years+ - NCT06280495RecruitingPhase 2/Phase 3
Targeted drugs plus chemo before surgery for colon cancer with liver spread
This trial tests whether adding two targeted drugs (serplulimab and bevacizumab) to standard chemotherapy before surgery can improve outcomes for people with colorectal cancer that has spread to the liver. It is for those whose cancer has certain genetic features and is considered resectable.
Guangzhou, GuangdongAges 18–75 - NCT06263088Recruiting
Equity in GI Cancer Care Study
This trial is looking for Black patients newly diagnosed with any stage of gastrointestinal cancer to help improve cancer care and make sure research includes everyone. By joining, you help doctors learn how to better support patients like you.
Cleveland, OhioAges 18 years+ - NCT06274788Recruiting
Safety study of long-term Omegaven for liver problems from IV nutrition
This study checks if children who need Omegaven for eight weeks or longer develop a lack of essential fats. It is for kids with liver issues caused by IV nutrition who cannot eat or digest food normally.
Fountain Valley, CaliforniaAges 1 day–17 years - NCT06252753Recruiting
Observational study of durvalumab for liver and bile duct cancer
This study looks at how well durvalumab (Imfinzi) works for people with liver or bile duct cancer. It follows your treatment as part of regular care to gather more information.
Birmingham, AlabamaAges 18–130 - NCT06218420RecruitingPhase 2
Radiation to bridge to liver transplant
This study tests whether a precise type of radiation (called stereotactic body radiotherapy or SBRT) can be used as a 'bridge' to keep your liver cancer from growing while you wait for a liver transplant. It may help more people stay healthy enough to receive a transplant.
ParisAges 18 years+ - NCT06227728Recruiting
Predicting immunotherapy response in advanced cancer
This study uses blood and tumor samples to find markers that predict whether immunotherapy will work for people with stage IV cancer. The goal is to better match treatments to patients.
Ho Chi Minh City, Hồ Chí MinhAges 18–80 - NCT06184152Recruiting
Comparing two scans to find liver cancer early
This trial compares two types of imaging scans (CEUS and AMRI) to see which one is better at finding liver cancer (HCC) in patients who have an unclear spot on their liver (an indeterminate nodule). It is for people with cirrhosis who have at least one such nodule but no confirmed liver cancer yet.
Ann Arbor, MichiganAges 18 years+ - NCT06198296RecruitingPhase 1
Armored CAR T cells for GPC3-positive solid tumors
This trial tests a new type of immunotherapy called CAR T cells that are trained to find and attack cancer cells with a specific marker (GPC3). The CAR T cells are also 'armored' with extra proteins (IL-15 and IL-21) to help them work better. It might be an option for adults with advanced solid tumors, especially liver cancer, that have not responded to standard treatments.
Houston, TexasAges Up to 21 years - NCT06191120Recruiting
FAPI PET scan for aggressive colorectal cancer liver metastases
This trial uses a special PET scan (FAPI) to detect a specific, more aggressive type of colorectal cancer (CMS4) in people who have liver tumors that can be surgically removed. The goal is to see if the scan can help doctors choose the best treatment for you.
Utrecht, UtrechtAges 18 years+ - NCT06205992Recruiting
Comparing 2D and 3D MRI scans for liver scarring and pressure
This study compares two types of MRI scans (2D and 3D) to see which is better at measuring liver scarring and high blood pressure in the liver's main vein. It is for people with cirrhosis who are already scheduled to have their liver vein pressure measured.
Shenyang, LiaoningAges 18–75 - NCT06175845Recruiting
Endoscopic radiofrequency ablation for bile duct cancer
This trial tests a minimally invasive treatment using heat (radiofrequency ablation) to destroy cancer cells in the bile duct. It's for patients whose bile duct cancer cannot be removed by surgery and who are also receiving systemic therapy.
BerlinAges 18 years+ - NCT06181409Recruiting
New scans to detect liver disease complications
This study uses two types of scans (MRI and ultrasound) to check for high pressure in the veins of your liver. It may help doctors find problems earlier without invasive tests.
Montreal, QuebecAges 18 years+ - NCT06160635Recruiting
D-SOLVE: Study of Hepatitis D treatments
This trial is testing treatments for people with chronic hepatitis D, a serious liver infection. If you have antibodies to the hepatitis D virus (HDV), you may be able to join and help find better ways to manage this condition.
HanoverAges 18 years+ - NCT06174272Recruiting
Better care after hospital for liver swelling
This trial tests a program to help people with cirrhosis and severe fluid swelling get better care after leaving the hospital. It focuses on guiding you through treatment with water pills and managing fluid buildup at home.
Hershey, PennsylvaniaAges 18 years+ - NCT06119997Recruiting
Liver fibrosis screening using simple blood tests in primary care
This trial uses a blood test (FIB-4) to find liver scarring (fibrosis) in people who haven't been tested before. It aims to catch advanced liver disease early, which can help you get treatment sooner.
GrenobleAges 18–70
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Common questions
- Are there clinical trials for liver?
- Yes. Clin2 currently lists 1,219 recruiting liver studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a liver trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a liver trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.